PKA and Epac1 Reduce Nek7 to Block the NLRP3 Inflammasome Proteins in the Retinal Vasculature
PKA and Epac1 regulated Nek7/NLRP3 signaling proteins. The schematic depicts the signaling pathway of PKA and Epac1 inhibition of Nek7 and NLRP3 signaling proteins to reduce retinal inflammation.
Publication
PKA and Epac1 Reduce Nek7 to Block the NLRP3 Inflammasome Proteins in the Retinal Vasculature. (2022) Li Liu, et al. Invest Ophthalmol Vis Sci. 2022 Jan;63(1):14. Figure: F9.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | Nek7 | NEK7 | ncbigene_symbol | NEK7 | 140609 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKAR1A | 5573 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKAR1B | 5575 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKAR2A | 5576 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKAR2B | 5577 |
| Word | Match | MeSH | Name | ChEBI |
|---|
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|---|---|---|---|
| Diabetic Retinopathy | NA | mesh:D003920 |