Schematic diagram to illustrate the ubiquitination of IRE1 by CHIP and the effect to the relevant signaling
Schematic diagram to illustrate the ubiquitination of IRE1 by CHIP and the effect to the relevant signaling.
Publication
Ubiquitination of Inositol-requiring Enzyme 1 (IRE1) by the E3 Ligase CHIP Mediates the IRE1/TRAF2/JNK Pathway. (2014) Xu Zhu, et al. J Biol Chem. 2014 Oct 31;289(44):30567-30577. Figure: F7.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Drosophila melanogaster | Invertebrates | IRE1 | IRE1 | ncbigene_symbol | Ire1 | 42358 |
| Drosophila melanogaster | Invertebrates | IRE1 | IRE1 | ncbigene_synonym | crc | 47767 |
| Drosophila melanogaster | Invertebrates | BIP| | BIP | ncbigene_symbol | bip | 249912 |
| Drosophila melanogaster | Invertebrates | BIP| | BIP | ncbigene_synonym | Hsc70-3 | 32133 |
| Drosophila melanogaster | Invertebrates | CHIP | CHIP | ncbigene_synonym | STUB1 | 34433 |
| Drosophila melanogaster | Invertebrates | CHIP | CHIP | ncbigene_synonym | Chi | 37837 |
| Drosophila melanogaster | Invertebrates | TRAF2 | TRAF2 | ncbigene_synonym | Traf6 | 31746 |
| Drosophila melanogaster | Invertebrates | JNK | JNK | ncbigene_synonym | bsk | 44801 |
| Drosophila melanogaster | Invertebrates | p38 | P38 | ncbigene_synonym | lic | 32257 |
| Drosophila melanogaster | Invertebrates | p38 | P38 | ncbigene_synonym | p38b | 34780 |
| Drosophila melanogaster | Invertebrates | p38 | P38 | ncbigene_synonym | Nurf-38 | 37922 |
| Drosophila melanogaster | Invertebrates | p38 | P38 | ncbigene_synonym | Ebp | 38009 |
| Drosophila melanogaster | Invertebrates | p38 | P38 | ncbigene_synonym | AIMP2 | 39690 |
| Drosophila melanogaster | Invertebrates | p38 | P38 | ncbigene_synonym | p38a | 42866 |
| Drosophila melanogaster | Invertebrates | p38 | P38 | ncbigene_synonym | Hrb87F | 48535 |
| Drosophila melanogaster | Invertebrates | p38 | P38 | ncbigene_synonym | p38c | 2768679 |
| Homo sapiens | Primates | IRE1 | IRE1 | ncbigene_synonym | ERN1 | 2081 |
| Homo sapiens | Primates | BIP| | BIP | ncbigene_synonym | GDF10 | 2662 |
| Homo sapiens | Primates | BIP| | BIP | ncbigene_synonym | HSPA5 | 3309 |
| Homo sapiens | Primates | CHIP | CHIP | ncbigene_synonym | STUB1 | 10273 |
| Homo sapiens | Primates | TRAF2 | TRAF2 | ncbigene_symbol | TRAF2 | 7186 |
| Homo sapiens | Primates | TRAF2 | TRAF2 | ncbigene_synonym | TANK | 10010 |
| Homo sapiens | Primates | JNK | JNK | ncbigene_synonym | MAPK8 | 5599 |
| Homo sapiens | Primates | JNK | JNK | famplex_relations | MAPK9 | 5601 |
| Homo sapiens | Primates | JNK | JNK | famplex_relations | MAPK10 | 5602 |
| Homo sapiens | Primates | p38 | P38 | ncbigene_synonym | CRK | 1398 |
| Homo sapiens | Primates | p38 | P38 | ncbigene_synonym | MAPK14 | 1432 |
| Homo sapiens | Primates | p38 | P38 | ncbigene_synonym | MAPK1 | 5594 |
| Homo sapiens | Primates | p38 | P38 | ncbigene_synonym | AIMP2 | 7965 |
| Homo sapiens | Primates | p38 | P38 | ncbigene_synonym | GRAP2 | 9402 |
| Homo sapiens | Primates | p38 | P38 | ncbigene_synonym | AHSA1 | 10598 |
| Homo sapiens | Primates | p38 | P38 | ncbigene_synonym | POLDIP2 | 26073 |
| Homo sapiens | Primates | p38 | P38 | famplex_relations | MAPK11 | 5600 |
| Homo sapiens | Primates | p38 | P38 | famplex_relations | MAPK12 | 6300 |
| Homo sapiens | Primates | p38 | P38 | famplex_relations | MAPK13 | 5603 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| Phosphate | NA | mesh:D010710 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|