Hypothetic pathways by which Pokemon regulates survivin expression
Hypothetic pathways by which Pokemon regulates survivin expression. p53 suppresses survivin expression and induces cell apoptosis or senescence [,]. Pokemon activates survivin signaling by suppressing the ARF/p53 pathway []. The present study shows that Pokemon also enhances survivin expression via direct binding to its promoter, promoting breast oncogenesis.
Publication
Pro-oncogene Pokemon promotes breast cancer progression by upregulating survivin expression. (2011) Xuyu Zu, et al. Breast Cancer Res. 2011;13(2):R26-R26. Figure: F5.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Drosophila melanogaster | Invertebrates | ARF | ARF | ncbigene_synonym | Arl1 | 39745 |
| Drosophila melanogaster | Invertebrates | ARF | ARF | ncbigene_synonym | Arf1 | 40506 |
| Drosophila melanogaster | Invertebrates | ARF | ARF | ncbigene_synonym | Arl2 | 40993 |
| Drosophila melanogaster | Invertebrates | p53 | P53 | ncbigene_symbol | p53 | 2768677 |
| Drosophila melanogaster | Invertebrates | p53 | P53 | ncbigene_synonym | betaTub60D | 37888 |
| Drosophila melanogaster | Invertebrates | p53 | P53 | ncbigene_synonym | hth | 41273 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | CkIIbeta | 32132 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Andorra | 32798 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Anp | 43595 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Acam | 44913 |
| Word | Match | MeSH | Name | ChEBI |
|---|
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|