Foetal liver-placenta-maternal liver excretory pathway
The foetal liver-placenta-maternal liver excretory pathway. Schematic representation of transporters (NTCP, sodium-taurocholate co-transporting polypeptide; OATP: Organic anion-transporting polypeptide), ATP-dependent pumps (BCRP: Breast cancer resistance protein; BSEP: Bile salt export pump; MDR: Multidrug resistance protein; MRP: Multidrug resistance-associated protein), and phase I (ALDH: Aldehyde dehydrogenase; BVR: Biliverdin reductase; CYP: Cytochrome P450 enzyme; HO: Heme oxygenase) and II (EH: Epoxide hydrolase; GST: Glutathione-S-transferase; NAT: N-acetyltransferase; ST: Sulfotransferase; UGT: UDP-glucuronosyl transferase) enzymes involved in excretion of biliary compounds during intrauterin life.
Publication
Excretion of biliary compounds during intrauterine life. (2009) Rocio IR Macias, et al. World J Gastroenterol. 2009 Feb 21;15(7):817-828. Figure: F1.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Drosophila melanogaster | Invertebrates | ATP-dependent | ATP | ncbigene_synonym | ATPsynbeta | 43829 |
| Drosophila melanogaster | Invertebrates | ATP-dependent | ATP | ncbigene_synonym | Atpalpha | 48971 |
| Drosophila melanogaster | Invertebrates | BVRa | BVRA | ncbigene_synonym | CG3597 | 33420 |
| Drosophila melanogaster | Invertebrates | ALDH | ALDH | ncbigene_symbol | Aldh | 34256 |
| Drosophila melanogaster | Invertebrates | ALDH | ALDH | ncbigene_synonym | Aldh-III | 45398 |
| Drosophila melanogaster | Invertebrates | Low | LOW | ncbigene_symbol | Low | 44325 |
| Drosophila melanogaster | Invertebrates | ЕН | EH | ncbigene_symbol | Eh | 42101 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstS1 | 36927 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstE12 | 37960 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstD1 | 41503 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstD2 | 48335 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstD3 | 48336 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstD4 | 48337 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstD5 | 48338 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstD6 | 48339 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstD7 | 48340 |
| Drosophila melanogaster | Invertebrates | GST | GST | ncbigene_synonym | GstD8 | 48341 |
| Drosophila melanogaster | Invertebrates | ST | ST | ncbigene_symbol | st | 39836 |
| Drosophila melanogaster | Invertebrates | UGT | UGT | ncbigene_synonym | Ugalt | 31255 |
| Drosophila melanogaster | Invertebrates | UGT | UGT | ncbigene_synonym | Uggt | 40055 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | CkIIbeta | 32132 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Andorra | 32798 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Anp | 43595 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Acam | 44913 |
| Drosophila melanogaster | Invertebrates | MRP1 | MRP1 | ncbigene_synonym | MRP | 34686 |
| Drosophila melanogaster | Invertebrates | MRP4 | MRP4 | ncbigene_symbol | Mrp4 | 41387 |
| Homo sapiens | Primates | ATP-dependent | ATP | ncbigene_synonym | ATP8A2 | 51761 |
| Homo sapiens | Primates | BVRa | BVRA | ncbigene_synonym | BLVRA | 644 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH1A1 | 216 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH1A2 | 8854 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH1A3 | 220 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH2 | 217 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH3A1 | 218 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH3A2 | 224 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH3B1 | 221 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH5A1 | 7915 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH7A1 | 501 |
| Homo sapiens | Primates | ALDH | ALDH | famplex_relations | ALDH9A1 | 223 |
| Homo sapiens | Primates | GST | GST | ncbigene_synonym | SLCO6A1 | 133482 |
| Homo sapiens | Primates | GST | GST | ncbigene_synonym | GSTK1 | 373156 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTA1 | 2938 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTA2 | 2939 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTA3 | 2940 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTA4 | 2941 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTA5 | 221357 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTM1 | 2944 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTM2 | 2946 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTM3 | 2947 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTM4 | 2948 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTM5 | 2949 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTO1 | 9446 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTO2 | 119391 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTP1 | 2950 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTT1 | 2952 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTT2 | 2953 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTZ1 | 2954 |
| Homo sapiens | Primates | GST | GST | famplex_relations | GSTT2B | 653689 |
| Homo sapiens | Primates | UGT1A1 | UGT1A1 | ncbigene_symbol | UGT1A1 | 54658 |
| Homo sapiens | Primates | UGT1A1 | UGT1A1 | ncbigene_synonym | UGT1A10 | 54575 |
| Homo sapiens | Primates | UGT1A1 | UGT1A1 | ncbigene_synonym | UGT1A8 | 54576 |
| Homo sapiens | Primates | UGT1A1 | UGT1A1 | ncbigene_synonym | UGT1A7 | 54577 |
| Homo sapiens | Primates | UGT1A1 | UGT1A1 | ncbigene_synonym | UGT1A6 | 54578 |
| Homo sapiens | Primates | UGT1A1 | UGT1A1 | ncbigene_synonym | UGT1A4 | 54657 |
| Homo sapiens | Primates | UGT | UGT | ncbigene_synonym | SLC35A2 | 7355 |
| Homo sapiens | Primates | UGT | UGT | ncbigene_synonym | UGT1A | 7361 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT1A2P | 54580 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT1A3 | 54659 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT1A5 | 54579 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT1A9 | 54600 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT1A11P | 54574 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT1A12P | 54573 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT1A13P | 404204 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2A1 | 10941 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2A2 | 574537 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2A3 | 79799 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B4 | 7363 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B7 | 7364 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B10 | 7365 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B11 | 10720 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B15 | 7366 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B17 | 7367 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B24P | 54572 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B25P | 54571 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B26P | 54570 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B27P | 54569 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B28 | 54490 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT2B29P | 54568 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT3A1 | 133688 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT3A2 | 167127 |
| Homo sapiens | Primates | UGT | UGT | famplex_relations | UGT8 | 7368 |
| Homo sapiens | Primates | NAT | NAT | ncbigene_synonym | BRD2 | 6046 |
| Homo sapiens | Primates | OATP1B1 | OATP1B1 | ncbigene_synonym | SLCO1B1 | 10599 |
| Homo sapiens | Primates | OATP1B3 | OATP1B3 | ncbigene_synonym | SLCO1B3 | 28234 |
| Homo sapiens | Primates | OATP4A1 | OATP4A1 | ncbigene_synonym | SLCO4A1 | 28231 |
| Homo sapiens | Primates | OATP2B1 | OATP2B1 | ncbigene_synonym | SLCO2B1 | 11309 |
| Homo sapiens | Primates | MRP1 | MRP1 | ncbigene_synonym | CD9 | 928 |
| Homo sapiens | Primates | MRP1 | MRP1 | ncbigene_synonym | MDM4 | 4194 |
| Homo sapiens | Primates | MRP1 | MRP1 | ncbigene_synonym | ABCC1 | 4363 |
| Homo sapiens | Primates | MRP1 | MRP1 | ncbigene_synonym | MSH3 | 4437 |
| Homo sapiens | Primates | MDR1 | MDR1 | ncbigene_synonym | ABCB1 | 5243 |
| Homo sapiens | Primates | MDR1 | MDR1 | ncbigene_synonym | TBC1D9 | 23158 |
| Homo sapiens | Primates | MRP3 | MRP3 | ncbigene_synonym | ABCC3 | 8714 |
| Homo sapiens | Primates | MRP2 | MRP2 | ncbigene_synonym | ABCC2 | 1244 |
| Homo sapiens | Primates | MRP2 | MRP2 | ncbigene_synonym | KLHL1 | 57626 |
| Homo sapiens | Primates | MRP2 | MRP2 | ncbigene_synonym | SYCE1L | 100130958 |
| Homo sapiens | Primates | NTCP | NTCP | ncbigene_synonym | SLC10A1 | 6554 |
| Homo sapiens | Primates | MRP4 | MRP4 | ncbigene_synonym | ABCC4 | 10257 |
| Homo sapiens | Primates | BCRP | BCRP | ncbigene_synonym | ABCG2 | 9429 |
| Homo sapiens | Primates | BSEP | BSEP | ncbigene_synonym | ABCB11 | 8647 |
| Word | Match | MeSH | Name | ChEBI |
|---|
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|