Map of fructose utilization pathway in A

Map of fructose utilization pathway in A. baylyi. Fructose utilization pathway produces fructose-1,6-biphosphate which should be a precursor for the biosynthesis of pentose phosphates and polysaccharides and for the tricarboxylic acid cycle. Model accordingly predicts growth with fructose as sole carbon source. Phenotyping experiments show no growth of A. baylyi with fructose as sole carbon source. Supposedly, the Embden-Meyerhof-Parnas (EMP) pathway may not operate in the glycolytic direction in A. baylyi, as already observed for glucose utilization [,]. See main text for details.
Map of fructose utilization pathway in A
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Publication

Iterative reconstruction of a global metabolic model of Acinetobacter baylyi ADP1 using high-throughput growth phenotype and gene essentiality data. (2008) Maxime Durot, et al. BMC Syst Biol. 2008;2:85-85. Figure: F5.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Acinetobacter baylyi ADP1 Bacteria ACIAD1990 ACIAD1990 ncbigene_synonym ptsP 45234352
Acinetobacter baylyi ADP1 Bacteria ACIAD1993 ACIAD1993 ncbigene_synonym ACIAD_RS09175 45234354
Acinetobacter baylyi ADP1 Bacteria ACIAD1992 ACIAD1992 ncbigene_synonym pfkB 45234353
Acinetobacter baylyi ADP1 Bacteria ACIAD1925 ACIAD1925 ncbigene_synonym fba 45234292
Acinetobacter baylyi ADP1 Bacteria ACIADO363 ACIAD0363 ncbigene_synonym tpiA 45232866
Drosophila melanogaster Invertebrates and AND ncbigene_synonym CkIIbeta 32132
Drosophila melanogaster Invertebrates and AND ncbigene_synonym Andorra 32798
Drosophila melanogaster Invertebrates and AND ncbigene_synonym Anp 43595
Drosophila melanogaster Invertebrates and AND ncbigene_synonym Acam 44913
Drosophila melanogaster Invertebrates PEP PEP ncbigene_symbol Pep 45961
Drosophila melanogaster Invertebrates PEP PEP ncbigene_synonym bgcn 47873
Drosophila melanogaster Invertebrates ATP ATP ncbigene_synonym ATPsynbeta 43829
Drosophila melanogaster Invertebrates ATP ATP ncbigene_synonym Atpalpha 48971
Drosophila melanogaster Invertebrates ADP ADP ncbigene_symbol adp 37073
Drosophila melanogaster Invertebrates EMP EMP ncbigene_symbol emp 37999
Drosophila melanogaster Invertebrates cycle CYCLE ncbigene_synonym CycE 34924
Drosophila melanogaster Invertebrates cycle CYCLE ncbigene_synonym cyc 40162
Homo sapiens Primates PEP PEP ncbigene_synonym PAEP 5047
Homo sapiens Primates PEP PEP ncbigene_synonym PREP 5550
Homo sapiens Primates PEP PEP ncbigene_synonym PTPN22 26191
Homo sapiens Primates ATP ATP ncbigene_synonym ATP8A2 51761
Homo sapiens Primates ADP ADP ncbigene_synonym WDTC1 23038
Homo sapiens Primates EMP EMP ncbigene_synonym MAEA 10296

Chemical mentions

Word Match MeSH Name ChEBI
fructose-1,6-bisphosphate keto-D-fructose 1,6-bisphosphate mesh:C029063 fructose-1,6-diphosphate chebi:16905
fructose-1-phosphate beta-D-fructopyranose 1-phosphate mesh:C032284 fructose-1-phosphate chebi:42320
dihydroxy-acetone Acetone mesh:D000096 acetone chebi:15347
fructose Fructose mesh:D005632 fructose chebi:28757
glyceraldehyde Glyceraldehyde mesh:D005985 glyceraldehyde chebi:5445
Pentose phosphates Pentoses mesh:D010429 pentose chebi:25901
3-phosphate NA mesh:D010710
phosphate NA mesh:D010710
pyruvate NA mesh:D011773
Tricarboxylic acid Tricarboxylic Acids mesh:D014233 tricarboxylic acid chebi:27093

Disease mentions

Word Match MeSH Name DOID