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                "figtitle": "ADP receptor P2Y12 is the capstone of the cross-talk between Ca2+ mobilization pathways dependent on Ca2+ ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets",
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                "figtitle": "Nanoparticles (NPs)-mediated systemic mRNA delivery to reverse trastuzumab resistance for effective breast cancer therapy",
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                "figtitle": "Proposed model for the regulation of virulence gene expression by WTA biosynthesis in CA-MRSA",
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                "figtitle": "Possible biosynthetic pathway of dysiherbols A–E",
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            {
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                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
                "figid": "PMC10034633__MBT2-16-726-g003",
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                "pmcid": "PMC10034633",
                "number": "F2",
                "figtitle": "Production of biofuels from C1 ‐gases with Clostridium and related bacteria—Recent advances",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
                "figid": "PMC10034640__MBT2-16-709-g004",
                "url": "https://pfocr.wikipathways.org/figures/PMC10034640__F1",
                "pmcid": "PMC10034640",
                "number": "F1",
                "figtitle": "Recent advances in producing food additive L‐malate: Chassis, substrate, pathway, fermentation regulation and application",
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                "organisms": "Saccharomyces cerevisiae, Glycine max, Theobroma cacao, Aspergillus niger, Komagataella pastoris, Yarrowia lipolytica, Aspergillus flavus, Aspergillus oryzae, Nakaseomyces glabratus, Aspergillus sp., Rhizopus arrhizus, Aureobasidium pullulans, Schizophyllum commune, Aspergillus carbonarius, Helianthus tuberosus, Zygosaccharomyces rouxii, Aspergillus niger ATCC 1015, Penicillium sclerotiorum, Ustilago trichophora, Penicillium viticola, Fuscoporia viticola, Escherichia coli, Bacillus subtilis, Corynebacterium glutamicum, Klebsiella pneumoniae, Bacillus subtilis subsp. subtilis str. 168, Escherichia coli str. K-12 substr. W3110, Synechococcus elongatus, Weizmannia coagulans, Thermobifida fusca, Prochlorococcus marinus, Escherichia coli C, Escherichia coli ATCC 8739, Homo sapiens, synthetic organisms",
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            {
                "figid": "PMC10034640__MBT2-16-709-g003",
                "url": "https://pfocr.wikipathways.org/figures/PMC10034640__F3",
                "pmcid": "PMC10034640",
                "number": "F3",
                "figtitle": "Recent advances in producing food additive L‐malate: Chassis, substrate, pathway, fermentation regulation and application",
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                "organisms": "Saccharomyces cerevisiae, Glycine max, Theobroma cacao, Aspergillus niger, Komagataella pastoris, Yarrowia lipolytica, Aspergillus flavus, Aspergillus oryzae, Nakaseomyces glabratus, Aspergillus sp., Rhizopus arrhizus, Aureobasidium pullulans, Schizophyllum commune, Aspergillus carbonarius, Helianthus tuberosus, Zygosaccharomyces rouxii, Aspergillus niger ATCC 1015, Penicillium sclerotiorum, Ustilago trichophora, Penicillium viticola, Fuscoporia viticola, Escherichia coli, Bacillus subtilis, Corynebacterium glutamicum, Klebsiella pneumoniae, Bacillus subtilis subsp. subtilis str. 168, Escherichia coli str. K-12 substr. W3110, Synechococcus elongatus, Weizmannia coagulans, Thermobifida fusca, Prochlorococcus marinus, Escherichia coli C, Escherichia coli ATCC 8739, Homo sapiens, synthetic organisms",
                "organisms_ner": "Bacillus subtilis subsp. subtilis str. 168, Homo sapiens, Drosophila melanogaster"
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            {
                "figid": "PMC10034769__fphar-14-1067402-g009",
                "url": "https://pfocr.wikipathways.org/figures/PMC10034769__F9",
                "pmcid": "PMC10034769",
                "number": "F9",
                "figtitle": "Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway",
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                "organisms": "Mus musculus, Rattus norvegicus, Homo sapiens, gut metagenome, Punica granatum",
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            {
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                "url": "https://pfocr.wikipathways.org/figures/PMC10034899__F1",
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                "figtitle": "Sirtuins in attenuating plaque vulnerability in atherosclerosis",
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                "organisms": "NA",
                "organisms_ner": "Danio rerio, Homo sapiens"
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            {
                "figid": "PMC10035050__fnut-10-1098715-g006",
                "url": "https://pfocr.wikipathways.org/figures/PMC10035050__F6",
                "pmcid": "PMC10035050",
                "number": "F6",
                "figtitle": "Sodium acetate regulates milk fat synthesis through the activation of GPR41/GPR43 signaling pathway",
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                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10035447__nihms-1878426-f0004",
                "url": "https://pfocr.wikipathways.org/figures/PMC10035447__F4",
                "pmcid": "PMC10035447",
                "number": "F4",
                "figtitle": "Dynamics and Sensitivity of Signaling Pathways",
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                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster"
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            {
                "figid": "PMC10035551__fimmu-14-1029438-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10035551__F1",
                "pmcid": "PMC10035551",
                "number": "F1",
                "figtitle": "Regulation of PD-1 and PD-L1 expression in sepsis",
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                "organisms": "Mus musculus, Rattus norvegicus, Homo sapiens, Candida albicans, Streptococcus pneumoniae, Cryptosporidium parvum, Human metapneumovirus, NA",
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            {
                "figid": "PMC10035662__fpls-14-1114172-g008",
                "url": "https://pfocr.wikipathways.org/figures/PMC10035662__F8",
                "pmcid": "PMC10035662",
                "number": "F8",
                "figtitle": "Comparative metabolomic profiling of Arabidopsis thaliana roots and leaves reveals complex response mechanisms induced by a seaweed extract",
                "year": "2023",
                "organisms": "Arabidopsis thaliana, Ascophyllum nodosum, Durvillaea potatorum, Homo sapiens",
                "organisms_ner": "Homo sapiens, Drosophila melanogaster"
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            {
                "figid": "PMC10035756__fonc-13-1059441-g005",
                "url": "https://pfocr.wikipathways.org/figures/PMC10035756__F5",
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                "number": "F5",
                "figtitle": "State-of-the-art therapeutic strategies for targeting cancer stem cells in prostate cancer",
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                "organisms": "Homo sapiens, Mus musculus",
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            {
                "figid": "PMC10035973__10142_2023_1022_Fig6_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10035973__F6",
                "pmcid": "PMC10035973",
                "number": "F6",
                "figtitle": "RNA-seq and microRNA association analysis to explore the pathogenic mechanism of DHAV-1 infection with DEHs",
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                "organisms": "NA",
                "organisms_ner": "Homo sapiens, Danio rerio"
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            {
                "figid": "PMC10036052__fonc-13-1120828-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036052__F1",
                "pmcid": "PMC10036052",
                "number": "F1",
                "figtitle": "Targeted therapy based on ubiquitin-specific proteases, signalling pathways and E3 ligases in non-small-cell lung cancer",
                "year": "2023",
                "organisms": "Homo sapiens, Mus musculus",
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            {
                "figid": "PMC10036181__jbm-2023-30-1-1f4",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036181__F4",
                "pmcid": "PMC10036181",
                "number": "F4",
                "figtitle": "Molecular and Cellular Crosstalk between Bone and Brain: Accessing Bidirectional Neural and Musculoskeletal Signaling during Aging and Disease",
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                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Danio rerio, Homo sapiens"
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            {
                "figid": "PMC10036213__nihms-1878350-f0004",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036213__F4",
                "pmcid": "PMC10036213",
                "number": "F4",
                "figtitle": "Liquid-liquid phase separation shapes signaling pathway function",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
                "figid": "PMC10036296__gr1_lrg",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036296__F1",
                "pmcid": "PMC10036296",
                "number": "F1",
                "figtitle": "An Evolving Understanding of the Basis and Management of Vascular Complications of COVID-19: Where Do We Go From Here?",
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                "organisms": "NA",
                "organisms_ner": "Homo sapiens, Danio rerio"
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            {
                "figid": "PMC10036381__fpls-14-1118313-g004",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036381__F4",
                "pmcid": "PMC10036381",
                "number": "F4",
                "figtitle": "Regulation of plant cell wall organisation under salt stress",
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                "organisms": "Arabidopsis thaliana, Nicotiana tabacum, Oryza sativa, Zea mays, Solanum lycopersicum, Embryophyta, Hordeum vulgare, PX clade, Malus domestica, Vitis vinifera, Sorghum bicolor, Medicago truncatula, Camellia sinensis, Brassica oleracea, Allium sativum, Capsicum annuum, Apium graveolens Dulce Group, Tracheophyta, Brachypodium distachyon, Capsicum frutescens, Fagopyrum esculentum, Panicum virgatum, Chenopodium quinoa, Cajanus cajan, Populus euphratica, Fagopyrum tataricum, Diospyros kaki, Apium graveolens, Alternaria solani, Betula platyphylla, Phyllostachys edulis, Amaranthus hypochondriacus, Eutrema salsugineum, Sophora alopecuroides, Salicornia europaea, Rheum australe, Avicennia officinalis, Hordeum marinum, Kosteletzkya pentacarpos, Populus davidiana, Chorispora bungeana, Populus sp., Bryum argenteum, Hordeum marinum subsp. marinum, Potentilla atrosanguinea",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
                "figid": "PMC10036441__fpls-14-1142753-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036441__F1",
                "pmcid": "PMC10036441",
                "number": "F1",
                "figtitle": "Phytomelatonin receptor 1-mediated signaling in plant growth and stress response",
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                "organisms": "Arabidopsis thaliana, Nicotiana tabacum, Oryza sativa, Zea mays, Glycine max, Solanum lycopersicum, Embryophyta, Solanum tuberosum, Triticum aestivum, Hordeum vulgare, PX clade, Malus domestica, Cucumis sativus, Magnoliopsida, Medicago truncatula, Nicotiana benthamiana, Botrytis cinerea, Medicago sativa, Pyrus communis, Gossypium hirsutum, Manihot esculenta, Vicia faba, Panax notoginseng, Moringa oleifera, Agrostis stolonifera, Cucumis sativus var. sativus, Malus prunifolia, Homo sapiens, Bos taurus, Xenopus laevis, Sar, Pseudomonas fluorescens, Tobacco mosaic virus",
                "organisms_ner": "Xenopus laevis, Drosophila melanogaster"
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            {
                "figid": "PMC10036441__fpls-14-1142753-g003",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036441__F3",
                "pmcid": "PMC10036441",
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                "figtitle": "Phytomelatonin receptor 1-mediated signaling in plant growth and stress response",
                "year": "2023",
                "organisms": "Arabidopsis thaliana, Nicotiana tabacum, Oryza sativa, Zea mays, Glycine max, Solanum lycopersicum, Embryophyta, Solanum tuberosum, Triticum aestivum, Hordeum vulgare, PX clade, Malus domestica, Cucumis sativus, Magnoliopsida, Medicago truncatula, Nicotiana benthamiana, Botrytis cinerea, Medicago sativa, Pyrus communis, Gossypium hirsutum, Manihot esculenta, Vicia faba, Panax notoginseng, Moringa oleifera, Agrostis stolonifera, Cucumis sativus var. sativus, Malus prunifolia, Homo sapiens, Bos taurus, Xenopus laevis, Sar, Pseudomonas fluorescens, Tobacco mosaic virus",
                "organisms_ner": "Arabidopsis thaliana, Solanum lycopersicum, Glycine max, Homo sapiens, Xenopus laevis, Drosophila melanogaster"
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            {
                "figid": "PMC10036442__109_2023_2289_Fig1_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036442__F1",
                "pmcid": "PMC10036442",
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                "figtitle": "Activation of aryl hydrocarbon receptor (AhR) in Alzheimer’s disease: role of tryptophan metabolites generated by gut host-microbiota",
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                "organisms": "Ruminococcus gnavus, Clostridium sporogenes, Thomasclavelia ramosa, Peptostreptococcus russellii, Mus musculus, Rattus norvegicus, gut metagenome, human metagenome, Homo sapiens",
                "organisms_ner": "NA"
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            {
                "figid": "PMC10036500__ga1",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036500__GA1",
                "pmcid": "PMC10036500",
                "number": "GA1",
                "figtitle": "MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335–5p signaling pathway",
                "year": "2023",
                "organisms": "Homo sapiens, Mus musculus",
                "organisms_ner": "Homo sapiens, Mus musculus, Danio rerio"
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            {
                "figid": "PMC10036537__41598_2023_31802_Fig1_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036537__F1",
                "pmcid": "PMC10036537",
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                "figtitle": "Shortening the sulfur cell cycle by a green approach for bio-production of extracellular metalloid-sulfide nanoparticles",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
                "figid": "PMC10036590__fonc-13-1132319-g004",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036590__F4",
                "pmcid": "PMC10036590",
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                "figtitle": "Targeting CLDN18.2 in cancers of the gastrointestinal tract: New drugs and new indications",
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                "organisms": "NA",
                "organisms_ner": "Danio rerio, Homo sapiens"
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            {
                "figid": "PMC10036653__gr8",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036653__F8",
                "pmcid": "PMC10036653",
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                "figtitle": "ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival",
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                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10036729__gr6",
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                "pmcid": "PMC10036729",
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                "figtitle": "Antioxidant and antiproliferative activity of Basella alba against colorectal cancer",
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                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
                "figid": "PMC10036758__fimmu-14-1146167-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10036758__F1",
                "pmcid": "PMC10036758",
                "number": "F1",
                "figtitle": "The complosome in health and disease",
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                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10036783__fpls-14-1131708-g005",
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                "figtitle": "Transcriptional and metabolic responses of apple to different potassium environments",
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                "organisms": "Arabidopsis thaliana, Nicotiana tabacum, Oryza sativa, Zea mays, Glycine max, Solanum lycopersicum, Embryophyta, Triticum aestivum, Hordeum vulgare, Malus domestica, Arachis hypogaea, Brassica napus, Helianthus annuus, Gossypium hirsutum, Ipomoea batatas, Picea abies, Panicum virgatum, Hordeum vulgare subsp. spontaneum, Ephedra major, Prunus mira, Glossodia major, Homo sapiens, Flectobacillus major, Prodaticus major",
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            {
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                "url": "https://pfocr.wikipathways.org/figures/PMC10037071__F6",
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                "figtitle": "Efficacy of Triphala extracts on the changes of obese fecal microbiome and metabolome in the human gut model",
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                "organisms": "NA",
                "organisms_ner": "NA"
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            {
                "figid": "PMC10037071__gr7",
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                "pmcid": "PMC10037071",
                "number": "F7",
                "figtitle": "Efficacy of Triphala extracts on the changes of obese fecal microbiome and metabolome in the human gut model",
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                "organisms": "NA",
                "organisms_ner": "NA"
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            {
                "figid": "PMC10037161__PBI-21-680-g002",
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                "figtitle": "High‐temperature stress in crops: male sterility, yield loss and potential remedy approaches",
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                "organisms": "NA",
                "organisms_ner": "Arabidopsis thaliana"
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            {
                "figid": "PMC10037167__j_med-2022-0615-ga001",
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                "figtitle": "Myostatin silencing inhibits podocyte apoptosis in membranous nephropathy through Smad3/PKA/NOX4 signaling pathway",
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            {
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                "figtitle": "Systemic treatment for metastatic colorectal cancer",
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            {
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                "figtitle": "Pathways of HIF-1A synthesis/degradation under normoxic and hypoxic conditions",
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                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
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                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
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                "figtitle": "Mechanism of STX5 involvement in HCC metastasis",
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                "organisms": "NA",
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                "figtitle": "Fasting: From Physiology to Pathology",
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                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10038327__uxac107f0003",
                "url": "https://pfocr.wikipathways.org/figures/PMC10038327__F3",
                "pmcid": "PMC10038327",
                "number": "F3",
                "figtitle": "Mitochondria as disease-relevant organelles in rheumatoid arthritis",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
            },
        
            {
                "figid": "PMC10038327__uxac107f0004",
                "url": "https://pfocr.wikipathways.org/figures/PMC10038327__F4",
                "pmcid": "PMC10038327",
                "number": "F4",
                "figtitle": "Mitochondria as disease-relevant organelles in rheumatoid arthritis",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
            },
        
            {
                "figid": "PMC10039030__41419_2023_5741_Fig7_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10039030__F7",
                "pmcid": "PMC10039030",
                "number": "F7",
                "figtitle": "Graphical abstract",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Arabidopsis thaliana"
            },
        
            {
                "figid": "PMC10039534__12943_2023_1761_Fig2_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10039534__F2",
                "pmcid": "PMC10039534",
                "number": "F2",
                "figtitle": "Unleashing the potential of combining FGFR inhibitor and immune checkpoint blockade for FGF/FGFR signaling in tumor microenvironment",
                "year": "2023",
                "organisms": "Homo sapiens, Mus musculus",
                "organisms_ner": "Mus musculus, Homo sapiens, Drosophila melanogaster"
            },
        
            {
                "figid": "PMC10039701__fuad010fig2",
                "url": "https://pfocr.wikipathways.org/figures/PMC10039701__F2",
                "pmcid": "PMC10039701",
                "number": "F2",
                "figtitle": "Bacterial virulence regulation through soluble peptidoglycan fragments sensing and response: knowledge gaps and therapeutic potential",
                "year": "2023",
                "organisms": "Escherichia coli, Staphylococcus aureus, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Bacillus subtilis, Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica, Klebsiella pneumoniae, Citrobacter rodentium, Acinetobacter baumannii, Pseudomonas aeruginosa PAO1, Neisseria gonorrhoeae, Enterococcus faecium, Enterobacter cloacae, Xanthomonas campestris, Rhodobacter capsulatus, Ralstonia solanacearum, Aeromonas hydrophila, Shewanella oneidensis, Stenotrophomonas maltophilia, Citrobacter freundii, Chromobacterium violaceum, Proteus vulgaris, Xanthomonas campestris pv. campestris, Shigella sonnei, Achromobacter sp., Achromobacter xylosoxidans, Dickeya dadantii, Pseudomonas aeruginosa C, Citrobacter koseri, Elizabethkingia meningoseptica, Achromobacter ruhlandii, Homo sapiens, Mus musculus, Caenorhabditis elegans, Severe acute respiratory syndrome coronavirus 2, Equus caballus, Bacteriophage sp., Citrus deliciosa",
                "organisms_ner": "Citrobacter freundii, Shigella sonnei, Pseudomonas aeruginosa PAO1, Stenotrophomonas maltophilia, Proteus vulgaris, Aeromonas hydrophila, Mus musculus, Homo sapiens, Drosophila melanogaster"
            },
        
            {
                "figid": "PMC10039784__gr1_lrg",
                "url": "https://pfocr.wikipathways.org/figures/PMC10039784__F1",
                "pmcid": "PMC10039784",
                "number": "F1",
                "figtitle": "Deficient radiation transcription response in COVID-19 patients",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
            },
        
            {
                "figid": "PMC10039885__41467_2023_37288_Fig1_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10039885__F1",
                "pmcid": "PMC10039885",
                "number": "F1",
                "figtitle": "Representative macrolide biosynthetic pathways",
                "year": "2023",
                "organisms": "Escherichia coli, Escherichia coli DH5alpha, Escherichia coli BL21DE3, Methanocaldococcus jannaschii, Streptomyces venezuelae, Cellulosimicrobium sp. 3-H, Pyxidicoccus fallax, Homo sapiens, H1N1 subtype, Expression vector pET-28",
                "organisms_ner": "Homo sapiens, Drosophila melanogaster"
            },
        
            {
                "figid": "PMC10040131__12967_2023_4031_Fig7_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040131__F7",
                "pmcid": "PMC10040131",
                "number": "F7",
                "figtitle": "PHF6 recruits BPTF to promote HIF-dependent pathway and progression in YAP-high breast cancer",
                "year": "2023",
                "organisms": "Homo sapiens, Mus musculus, Armoracia rusticana",
                "organisms_ner": "Homo sapiens, Mus musculus"
            },
        
            {
                "figid": "PMC10040407__41392_2023_1336_Fig8_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040407__F8",
                "pmcid": "PMC10040407",
                "number": "F8",
                "figtitle": "Exosomes secreted from cardiomyocytes suppress the sensitivity of tumor ferroptosis in ischemic heart failure",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
            },
        
            {
                "figid": "PMC10040548__fimmu-14-1121495-g005",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040548__F5",
                "pmcid": "PMC10040548",
                "number": "F5",
                "figtitle": "Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis",
                "year": "2023",
                "organisms": "Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv, Brucella abortus, Streptococcus agalactiae, Homo sapiens, Mus musculus, Saccharomyces cerevisiae, Onchocerca volvulus",
                "organisms_ner": "Mus musculus, Homo sapiens, Mycobacterium tuberculosis H37Rv, Drosophila melanogaster"
            },
        
            {
                "figid": "PMC10040548__fimmu-14-1121495-g006",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040548__F6",
                "pmcid": "PMC10040548",
                "number": "F6",
                "figtitle": "Sirtuin-dependent metabolic and epigenetic regulation of macrophages during tuberculosis",
                "year": "2023",
                "organisms": "Mycobacterium tuberculosis, Homo sapiens",
                "organisms_ner": "Homo sapiens, Drosophila melanogaster"
            },
        
            {
                "figid": "PMC10040549__fnut-10-1090338-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040549__F1",
                "pmcid": "PMC10040549",
                "number": "F1",
                "figtitle": "Ferroptosis in non-alcoholic liver disease: Molecular mechanisms and therapeutic implications",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
            },
        
            {
                "figid": "PMC10040566__fimmu-14-1094823-g002",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040566__F2",
                "pmcid": "PMC10040566",
                "number": "F2",
                "figtitle": "Th-17 cells and IL-17 in the metastatic spread of breast cancer: As a means of prognosis and therapeutic target",
                "year": "2023",
                "organisms": "Homo sapiens, Mus musculus, Corynephage beta",
                "organisms_ner": "Homo sapiens, Mus musculus, Danio rerio"
            },
        
            {
                "figid": "PMC10040566__fimmu-14-1094823-g003",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040566__F3",
                "pmcid": "PMC10040566",
                "number": "F3",
                "figtitle": "Th-17 cells and IL-17 in the metastatic spread of breast cancer: As a means of prognosis and therapeutic target",
                "year": "2023",
                "organisms": "Homo sapiens, Mus musculus, Corynephage beta",
                "organisms_ner": "Mus musculus, Homo sapiens, Danio rerio"
            },
        
            {
                "figid": "PMC10040578__fphar-14-1113810-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040578__F1",
                "pmcid": "PMC10040578",
                "number": "F1",
                "figtitle": "Mechanism of action of paeoniae radix rubra–angelicae sinensis radix drug pair in the treatment of rheumatoid arthritis through PI3K/AKT/NFKB signaling pathway",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
            },
        
            {
                "figid": "PMC10040578__fphar-14-1113810-g010",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040578__F10",
                "pmcid": "PMC10040578",
                "number": "F10",
                "figtitle": "Mechanism of action of paeoniae radix rubra–angelicae sinensis radix drug pair in the treatment of rheumatoid arthritis through PI3K/AKT/NFKB signaling pathway",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
            },
        
            {
                "figid": "PMC10040598__fimmu-14-1052756-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040598__F1",
                "pmcid": "PMC10040598",
                "number": "F1",
                "figtitle": "The inflammasome in insulin resistance and type 2 diabetes mellitus",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
            },
        
            {
                "figid": "PMC10040598__fimmu-14-1052756-g003",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040598__F3",
                "pmcid": "PMC10040598",
                "number": "F3",
                "figtitle": "The inflammasome in insulin resistance and type 2 diabetes mellitus",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10040615__dmj-2022-0270f1",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040615__F1",
                "pmcid": "PMC10040615",
                "number": "F1",
                "figtitle": "Multiple Roles of Sirtuin 6 in Adipose Tissue Inflammation",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster"
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            {
                "figid": "PMC10040733__gr5",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040733__F5",
                "pmcid": "PMC10040733",
                "number": "F5",
                "figtitle": "Phosphate depletion in insulin-insensitive skeletal muscle drives AMPD activation and sarcopenia in chronic kidney disease",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster"
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            {
                "figid": "PMC10040775__fvets-10-1138564-g0005",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040775__F5",
                "pmcid": "PMC10040775",
                "number": "F5",
                "figtitle": "Low-protein maternal diet during gestation affects the expression of key pancreatic Beta-cell genes and the methylation status of the regulatory region of the MafA gene in the offspring of Wistar rats",
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                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10040812__gr8",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040812__F8",
                "pmcid": "PMC10040812",
                "number": "F8",
                "figtitle": "Signaling protein GIV/Girdin mediates the Nephrin-dependent insulin secretion of pancreatic islet B cells in response to high glucose",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
                "figid": "PMC10040851__fgene-14-1105673-g006",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040851__F6",
                "pmcid": "PMC10040851",
                "number": "F6",
                "figtitle": "Single-cell atlas reveals shared and distinct immune responses and metabolic profiles in SARS-CoV-2 and HIV-1 infections",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10040865__fendo-14-1128622-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10040865__F1",
                "pmcid": "PMC10040865",
                "number": "F1",
                "figtitle": "The immune system by the insulin receptor in health and disease",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
            },
        
            {
                "figid": "PMC10041388__MCO2-4-e218-g002",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041388__F1",
                "pmcid": "PMC10041388",
                "number": "F1",
                "figtitle": "Metabolic reprogramming in cancer: Mechanisms and therapeutics",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10041467__adr-7-adr220071-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041467__F1",
                "pmcid": "PMC10041467",
                "number": "F1",
                "figtitle": "Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer’s Disease",
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                "organisms": "Mus musculus, Rattus norvegicus, Cricetus cricetus, Homo sapiens, Macaca mulatta, Drosophila melanogaster, Xenopus laevis, gut metagenome, prion, Cyamopsis tetragonoloba",
                "organisms_ner": "Mus musculus, Homo sapiens, Rattus norvegicus, Drosophila melanogaster, Macaca mulatta, Danio rerio"
            },
        
            {
                "figid": "PMC10041467__adr-7-adr220071-g011",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041467__F11",
                "pmcid": "PMC10041467",
                "number": "F11",
                "figtitle": "Pathological Effects of Circulating Hydrophobic Bile Acids in Alzheimer’s Disease",
                "year": "2023",
                "organisms": "Mus musculus, Rattus norvegicus, Cricetus cricetus, Homo sapiens, Macaca mulatta, Drosophila melanogaster, Xenopus laevis, gut metagenome, prion, Cyamopsis tetragonoloba",
                "organisms_ner": "Mus musculus, Drosophila melanogaster, Homo sapiens, Danio rerio"
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            {
                "figid": "PMC10041518__41568_2023_557_Fig1_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041518__F1",
                "pmcid": "PMC10041518",
                "number": "F1",
                "figtitle": "Biosynthetic pathways for pyrimidine and purine nucleotides, relevant inhibitors and oncogenic regulators",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
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            {
                "figid": "PMC10041518__41568_2023_557_Fig2_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041518__F2",
                "pmcid": "PMC10041518",
                "number": "F2",
                "figtitle": "Nucleotides fuel cancer cell growth and proliferation",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
            },
        
            {
                "figid": "PMC10041518__41568_2023_557_Fig3_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041518__F3",
                "pmcid": "PMC10041518",
                "number": "F3",
                "figtitle": "Altered nucleoside handling facilitates cancer cell immune evasion",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens, Drosophila melanogaster"
            },
        
            {
                "figid": "PMC10041518__41568_2023_557_Fig4_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041518__F4",
                "pmcid": "PMC10041518",
                "number": "F4",
                "figtitle": "Supraphysiological GTP abundance promotes metastasis through the activation of RHO-family GTPases",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
            },
        
            {
                "figid": "PMC10041518__41568_2023_557_Fig5_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041518__F5",
                "pmcid": "PMC10041518",
                "number": "F5",
                "figtitle": "Hyperactive nucleotide synthesis confers resistance to a range of therapeutic interventions",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
            },
        
            {
                "figid": "PMC10041541__jm2c01406_0013",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041541__F13",
                "pmcid": "PMC10041541",
                "number": "F13",
                "figtitle": "From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment",
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                "organisms": "Nicotiana tabacum, Allium cepa, Allium sativum, Catharanthus roseus, Petroselinum crispum, Cinnamomum verum, Brassica juncea, Thymus vulgaris, Syzygium aromaticum, Taxus brevifolia, Myristica fragrans, Camptotheca acuminata, Myrrhis odorata, Anethum graveolens, Brassica nigra, Piper auritum, Cinnamomum burmanni, Ocotea odorifera, Zanthoxylum rhetsum, Sassafras albidum, Mus musculus, Rattus norvegicus, Homo sapiens, Staphylococcus aureus, Hepatitis B virus, NA",
                "organisms_ner": "Mus musculus, Drosophila melanogaster"
            },
        
            {
                "figid": "PMC10041541__jm2c01406_0007",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041541__F7",
                "pmcid": "PMC10041541",
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                "figtitle": "From Natural Sources to Synthetic Derivatives: The Allyl Motif as a Powerful Tool for Fragment-Based Design in Cancer Treatment",
                "year": "2023",
                "organisms": "Nicotiana tabacum, Allium cepa, Allium sativum, Catharanthus roseus, Petroselinum crispum, Cinnamomum verum, Brassica juncea, Thymus vulgaris, Syzygium aromaticum, Taxus brevifolia, Myristica fragrans, Camptotheca acuminata, Myrrhis odorata, Anethum graveolens, Brassica nigra, Piper auritum, Cinnamomum burmanni, Ocotea odorifera, Zanthoxylum rhetsum, Sassafras albidum, Mus musculus, Rattus norvegicus, Homo sapiens, Staphylococcus aureus, Hepatitis B virus, NA",
                "organisms_ner": "Homo sapiens, Drosophila melanogaster"
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            {
                "figid": "PMC10041561__gr15",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041561__F15",
                "pmcid": "PMC10041561",
                "number": "F15",
                "figtitle": "Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Drosophila melanogaster, Homo sapiens"
            },
        
            {
                "figid": "PMC10041561__gr17",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041561__F17",
                "pmcid": "PMC10041561",
                "number": "F17",
                "figtitle": "Bakuchiol and Ethyl (Linoleate/Oleate) Synergistically Modulate Endocannabinoid Tone in Keratinocytes and Repress Inflammatory Pathway mRNAs",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
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            {
                "figid": "PMC10041595__10.1177_15330338231161141-fig5",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041595__F5",
                "pmcid": "PMC10041595",
                "number": "F5",
                "figtitle": "NRF1 Regulates the Epithelial Mesenchymal Transition of Breast Cancer by Modulating ROS Homeostasis",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Homo sapiens"
            },
        
            {
                "figid": "PMC10041598__10.1177_11786361231162720-fig4",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041598__F4",
                "pmcid": "PMC10041598",
                "number": "F4",
                "figtitle": "Implication of Short-Chain Fatty Acids in Obesity and Diabetes",
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                "organisms": "Fusobacterium nucleatum, Faecalibacterium prausnitzii, Akkermansia muciniphila, Lacticaseibacillus paracasei, Bifidobacterium animalis subsp. lactis, Eubacterium rectale, Prevotella copri, Clostridium leptum, Megasphaera elsdenii, Blautia coccoides, Roseburia inulinivorans, Clostridium symbiosum, Blautia hydrogenotrophica, Peptoniphilus asaccharolyticus, Clostridium sporosphaeroides, Coprococcus catus, Prevotella stercorea, Acidaminococcus fermentans, Mus musculus, Rattus norvegicus, Spermophilus dauricus, gut metagenome, human gut metagenome, Homo sapiens, Carya myristiciformis",
                "organisms_ner": "Homo sapiens, Mus musculus, Rattus norvegicus"
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            {
                "figid": "PMC10041793__12870_2023_4167_Fig6_HTML",
                "url": "https://pfocr.wikipathways.org/figures/PMC10041793__F6",
                "pmcid": "PMC10041793",
                "number": "F6",
                "figtitle": "Cyanoalanine synthase and alternative oxidase in promoting salt stress tolerance in Arabidopsis thaliana",
                "year": "2023",
                "organisms": "NA",
                "organisms_ner": "Arabidopsis thaliana"
            },
        
            {
                "figid": "PMC10042294__fcell-11-1086964-g002",
                "url": "https://pfocr.wikipathways.org/figures/PMC10042294__F2",
                "pmcid": "PMC10042294",
                "number": "F2",
                "figtitle": "Dark side of mRNA translation and the translation machinery in glioblastoma",
                "year": "2023",
                "organisms": "Saccharomyces cerevisiae, Aglaia silvestris, Homo sapiens, Mus musculus, Danio rerio",
                "organisms_ner": "Homo sapiens, Mus musculus, Drosophila melanogaster"
            },
        
            {
                "figid": "PMC10042294__fcell-11-1086964-g007",
                "url": "https://pfocr.wikipathways.org/figures/PMC10042294__F7",
                "pmcid": "PMC10042294",
                "number": "F7",
                "figtitle": "Dark side of mRNA translation and the translation machinery in glioblastoma",
                "year": "2023",
                "organisms": "Saccharomyces cerevisiae, Aglaia silvestris, Homo sapiens, Mus musculus, Danio rerio",
                "organisms_ner": "Mus musculus, Homo sapiens, Drosophila melanogaster"
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            {
                "figid": "PMC10042385__fbioe-11-1167123-g001",
                "url": "https://pfocr.wikipathways.org/figures/PMC10042385__F1",
                "pmcid": "PMC10042385",
                "number": "F1",
                "figtitle": "Bioconversion of inorganic selenium to less toxic selenium forms by microbes: A review",
                "year": "2023",
                "organisms": "Saccharomyces cerevisiae, Oryza sativa, Agaricus bisporus, Helianthus annuus, Brassica oleracea, Allium cepa, Allium sativum, Chlorophyta, Lentinula edodes, Cyberlindnera jadinii, Hericium erinaceus, Saccharomyces boulardii nom. inval., Nannochloropsis oceanica, Bertholletia excelsa, Phellinus igniarius, Lignosus rhinocerotis, Cardamine hupingshanensis, Escherichia coli, Bacillus subtilis, Klebsiella pneumoniae, Enterococcus faecalis, Enterobacter cloacae, Staphylococcus carnosus, Weissella confusa, Thauera selenatis, Stenotrophomonas maltophilia SeITE02, Bacillus paralicheniformis, Gallus gallus, Cyprinus carpio, Oreochromis niloticus, Scombridae gen. sp., Mus musculus, Rattus norvegicus, Homo sapiens, Ovis aries, Cyanea capillata",
                "organisms_ner": "Drosophila melanogaster"
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            {
                "figid": "PMC10055176__nihpp-2023.03.15.532439v2-f0008",
                "url": "https://pfocr.wikipathways.org/figures/PMC10055176__F8",
                "pmcid": "PMC10055176",
                "number": "F8",
                "figtitle": "Changes in Environmental Stress over COVID-19 Pandemic Likely Contributed to Failure to Replicate Adiposity Phenotype Associated with Krtcap3",
                "year": "2023",
                "organisms": "NA",
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                "figtitle": "Regulatory Mechanism of Iguratimod on Signaling Pathway (IFN, interferon; TNF, Tumor necrosis factor; IL, Interleukin; Th, helper T cells; Treg, Regulatory T cells)",
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                "figtitle": "Metabolic pathway of prenylated flavonoids in plants",
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                "figtitle": "Apelin signaling pathway with differentially expressed proteins (DEPs)",
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                "figtitle": "WNT signaling pathway with differentially expressed proteins (DEPs)",
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                "figtitle": "Results summarized in this paper",
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