Fibrotic Response of Human Trabecular Meshwork Cells to Transforming Growth Factor-Beta 3 and Autotaxin in Aqueous Humor
Potential mechanisms of TGF-β3-mediated ATX expression and fibrotic changes in HTM cells. ATX expression and fibrotic changes appeared to be partially mediated by the canonical pathway, as well as the noncanonical pathway.
Publication
Fibrotic Response of Human Trabecular Meshwork Cells to Transforming Growth Factor-Beta 3 and Autotaxin in Aqueous Humor. (2022) Mengxuan Liu, et al. Biomolecules. 2022 Sep;12(9):1231. Figure: F8.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | TGF-B3 | TGF-B3 | ncbigene_synonym | TGFB3 | 7043 |
| Homo sapiens | Primates | STAT3 | STAT3 | ncbigene_symbol | STAT3 | 6774 |
| Homo sapiens | Primates | ATX | ATX | ncbigene_synonym | ENPP2 | 5168 |
| Homo sapiens | Primates | ATX | ATX | ncbigene_synonym | SMG1 | 23049 |
| Homo sapiens | Primates | ATX | ATX | ncbigene_synonym | DMBX1 | 127343 |
| Homo sapiens | Primates | LPA | LPA | ncbigene_symbol | LPA | 4018 |
| Homo sapiens | Primates | Rho | RHO | ncbigene_symbol | RHO | 6010 |
| Homo sapiens | Primates | Rho | RHO | ncbigene_synonym | RHOD | 29984 |
| Homo sapiens | Primates | Rho | RHO | famplex_relations | RHOA | 387 |
| Homo sapiens | Primates | Rho | RHO | famplex_relations | RHOB | 388 |
| Homo sapiens | Primates | Rho | RHO | famplex_relations | RHOC | 389 |
| Homo sapiens | Primates | JNK | JNK | ncbigene_synonym | MAPK8 | 5599 |
| Homo sapiens | Primates | JNK | JNK | famplex_relations | MAPK9 | 5601 |
| Homo sapiens | Primates | JNK | JNK | famplex_relations | MAPK10 | 5602 |
| Homo sapiens | Primates | COL1A1,CTGF | CTGF | ncbigene_synonym | CCN2 | 1490 |
| Homo sapiens | Primates | COL1A1,CTGF | COL1A1 | ncbigene_symbol | COL1A1 | 1277 |
| Homo sapiens | Primates | a-SMA | ASMA | ncbigene_synonym | ACTA1 | 58 |
| Homo sapiens | Primates | TGF-B1 | TGF-B1 | ncbigene_synonym | TGFB1 | 7040 |
| Homo sapiens | Primates | TGF-B2 | TGF-B2 | ncbigene_synonym | TGFB2 | 7042 |
| Homo sapiens | Primates | Smad3 | SMAD3 | ncbigene_symbol | SMAD3 | 4088 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| LPA | NA | mesh:C522988 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|