Pathways of acetate metabolism

Pathways of acetate metabolism. Acetate can be produced via the Pta-AckA pathway or PoxB and consumed via the AckA-Pta pathway or Acs. Acetyl-CoA can then enter the TCA cycle or the glyoxylate bypass. Labeled genes are those used in this study.
Pathways of acetate metabolism
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Publication

Extracellular Acidic pH Inhibits Acetate Consumption by Decreasing Gene Transcription of the Tricarboxylic Acid Cycle and the Glyoxylate Shunt. (2019) James S. Orr, et al. J Bacteriol. 2019 Jan 15;201(2):e00410-18. Figure: F1.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Escherichia coli str. K-12 substr. MG1655 Bacteria poxB POXB ncbigene_symbol poxB 946132
Escherichia coli str. K-12 substr. MG1655 Bacteria acs ACS ncbigene_symbol acs 948572
Escherichia coli str. K-12 substr. MG1655 Bacteria ackA ACKA ncbigene_symbol ackA 946775
Escherichia coli str. K-12 substr. MG1655 Bacteria pta PTA ncbigene_symbol pta 946778
Escherichia coli str. K-12 substr. MG1655 Bacteria gltA GLTA ncbigene_symbol gltA 945323
Escherichia coli str. K-12 substr. MG1655 Bacteria mdh MDH ncbigene_symbol mdh 947854
Escherichia coli str. K-12 substr. MG1655 Bacteria aceA ACEA ncbigene_symbol aceA 948517
Escherichia coli str. K-12 substr. MG1655 Bacteria icd ICD ncbigene_symbol icd 945702
Escherichia coli str. K-12 substr. MG1655 Bacteria sucA SUCA ncbigene_symbol sucA 945303

Chemical mentions

Word Match MeSH Name ChEBI
Acetyl CoA Acetyl Coenzyme A mesh:D000105 acetyl-CoA chebi:15351
Acetate Acetates mesh:D000085 acetate ester chebi:47622
Acetyl NA mesh:C011632
Phosphate NA mesh:D010710
Oxaloacetate NA mesh:D010071
Acetyl CoA Citrate NA mesh:C102006
Glyoxylate cis-aconitate NA mesh:C043607
Succinate Succinates mesh:D013386 succinate chebi:26806
Isocitrate NA mesh:D007523
Succinyl-CoA a-ketoglutarate NA mesh:C029743

Disease mentions

Word Match MeSH Name DOID