Paracellular and transcellular transport in the intestinal epithelium

Paracellular and transcellular transport in the intestinal epithelium. The enterocytes form a polarized single cell layer. The apical side, characterized with villi, is in contact with the intestinal lumen. The epithelial cells are tied together by the tight junction complexes. Several transporter pathways facilitate transport from the apical to the basolateral side. Transcellular transport is mediated by active transporters or by endocytosis–transcytosis–exocytosis. Paracellular transport is via either the pore pathway or the leak pathway.
Paracellular and transcellular transport in the intestinal epithelium
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Publication

Intestinal Barrier Function in Chronic Kidney Disease. (2018) Björn Meijers, et al. Toxins (Basel). 2018 Jul;10(7):298. Figure: F1.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Mus musculus Rodents large LARGE ncbigene_synonym Large1 16795
Mus musculus Rodents H20 H20 ncbigene_symbol H20 109807
Mus musculus Rodents CLDN-1 CLDN1 ncbigene_symbol Cldn1 12737
Mus musculus Rodents CLDN-21 CLDN21 ncbigene_synonym Cldn25 100042785
Mus musculus Rodents CLDN-2 CLDN2 ncbigene_symbol Cldn2 12738
Mus musculus Rodents MLCK MLCK ncbigene_synonym Mylk 107589
Mus musculus Rodents MLCK MLCK ncbigene_synonym Mylk3 213435
Homo sapiens Primates large LARGE ncbigene_synonym LARGE1 9215
Homo sapiens Primates CLDN-1 CLDN1 ncbigene_symbol CLDN1 9076
Homo sapiens Primates CLDN-21 CLDN21 ncbigene_synonym CLDN22 53842
Homo sapiens Primates CLDN-21 CLDN21 ncbigene_synonym CLDN24 100132463
Homo sapiens Primates CLDN-2 CLDN2 ncbigene_symbol CLDN2 9075
Homo sapiens Primates MLCK MLCK ncbigene_synonym MYLK 4638
Homo sapiens Primates MLCK MLCK ncbigene_synonym MYLK2 85366
Homo sapiens Primates MLCK MLCK ncbigene_synonym MYLK3 91807

Chemical mentions

Word Match MeSH Name ChEBI
O Superoxides mesh:D013481 superoxide chebi:18421
Na Sodium mesh:D012964 sodium-23 atom chebi:52634
H20 Hydrogen mesh:D006859 dihydrogen chebi:18276

Disease mentions

Word Match MeSH Name DOID