Path diagram of the nuclear factor kappa B (NFKB) signalling pathway

The path diagram of the nuclear factor kappa B (NF-κB) signalling pathway. The highlighted genes represent heart failure-associated genes.
Path diagram of the nuclear factor kappa B (NFKB) signalling pathway

Publication

Investigating the Mechanisms of Action of Depside Salt from Salvia miltiorrhiza Using Bioinformatic Analysis. (2017) Hua Li, et al. Evid Based Complement Alternat Med. 2017;2017:5671860. Figure: F4.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Drosophila melanogaster Invertebrates NF-KB NF-KB ncbigene_synonym Dif 35045
Drosophila melanogaster Invertebrates NF-KB NF-KB ncbigene_synonym dl 35047
Drosophila melanogaster Invertebrates NF-KB NF-KB ncbigene_synonym Rel 41087
Drosophila melanogaster Invertebrates EGF EGF ncbigene_synonym Egfr 37455
Drosophila melanogaster Invertebrates IL-1 IL-1 ncbigene_synonym JIL-1 39241
Drosophila melanogaster Invertebrates 11.IR/TLR TLR ncbigene_synonym 18w 37277
Drosophila melanogaster Invertebrates 11.IR/TLR TLR ncbigene_synonym tok 42944
Drosophila melanogaster Invertebrates 11.IR/TLR TLR ncbigene_synonym tlr-2 44349
Drosophila melanogaster Invertebrates BR3 BR3 ncbigene_synonym mol 34872
Drosophila melanogaster Invertebrates TRAF TRAF ncbigene_synonym Traf6 31746
Drosophila melanogaster Invertebrates TRAF TRAF ncbigene_synonym Traf4 33638
Drosophila melanogaster Invertebrates Ras RAS ncbigene_symbol ras 43873
Drosophila melanogaster Invertebrates Ras RAS ncbigene_synonym Ras64B 38494
Drosophila melanogaster Invertebrates Ras RAS ncbigene_synonym Ras85D 41140
Drosophila melanogaster Invertebrates RIP RIP ncbigene_symbol rip 44045
Drosophila melanogaster Invertebrates RIP RIP ncbigene_synonym ripp 246815
Drosophila melanogaster Invertebrates MEKK MEKK ncbigene_synonym Mekk1 42253
Drosophila melanogaster Invertebrates NIK NIK ncbigene_symbol Ni-K 252004
Drosophila melanogaster Invertebrates NIK NIK ncbigene_synonym msn 44030
Drosophila melanogaster Invertebrates PAR PAR ncbigene_symbol par 5656961
Drosophila melanogaster Invertebrates PAR PAR ncbigene_synonym para 32619
Drosophila melanogaster Invertebrates PAR PAR ncbigene_synonym par-6 32752
Drosophila melanogaster Invertebrates (RAF RAF ncbigene_symbol Raf 31221
Drosophila melanogaster Invertebrates Cot COT ncbigene_synonym mir-ban 12798547
Drosophila melanogaster Invertebrates ÁBIN- BIN ncbigene_symbol bin 38766
Drosophila melanogaster Invertebrates p50 P50 ncbigene_synonym Hrb27C 33968
Drosophila melanogaster Invertebrates p50 P50 ncbigene_synonym betaTub60D 37888
Drosophila melanogaster Invertebrates p50 P50 ncbigene_synonym Rpt5 42805
Drosophila melanogaster Invertebrates p50 P50 ncbigene_synonym DCTN2-p50 44086
Drosophila melanogaster Invertebrates p65 P65 ncbigene_synonym wash 36311
Drosophila melanogaster Invertebrates pos/RelA POS ncbigene_symbol Pos 43762
Drosophila melanogaster Invertebrates PKA PKA ncbigene_synonym Pka-C1 34284
Drosophila melanogaster Invertebrates PKA PKA ncbigene_synonym Pka-R2 36041
Drosophila melanogaster Invertebrates PKA PKA ncbigene_synonym Pka-C3 39733
Drosophila melanogaster Invertebrates PKA PKA ncbigene_synonym Pka-R1 40305
Drosophila melanogaster Invertebrates PKA PKA ncbigene_synonym Pka-C2 43644
Drosophila melanogaster Invertebrates NAK NAK ncbigene_symbol Nak 35154
Drosophila melanogaster Invertebrates NAK NAK ncbigene_synonym Atpalpha 48971
Drosophila melanogaster Invertebrates GSK GSK ncbigene_synonym sgg 31248
Drosophila melanogaster Invertebrates AB AB ncbigene_symbol ab 34560
Drosophila melanogaster Invertebrates AB AB ncbigene_synonym Appl 31002
Drosophila melanogaster Invertebrates CHP/p00 CHP ncbigene_symbol chp 43690
Drosophila melanogaster Invertebrates CHP/p00 CHP ncbigene_synonym NA 31293
Drosophila melanogaster Invertebrates CHP/p00 CHP ncbigene_synonym mora 42874
Drosophila melanogaster Invertebrates pes/RelA PES ncbigene_symbol pes 34087
Drosophila melanogaster Invertebrates All ALI ncbigene_symbol ali 5658436
Drosophila melanogaster Invertebrates All ALI ncbigene_synonym alpha-Est7 40901
Drosophila melanogaster Invertebrates All A11 ncbigene_synonym gus 35478
Homo sapiens Primates NF-KB NF-KB ncbigene_synonym NFKB1 4790
Homo sapiens Primates IL2 IL2 ncbigene_symbol IL2 3558
Homo sapiens Primates IL2/4|| IL4 ncbigene_symbol IL4 3565
Homo sapiens Primates RANKL RANKL ncbigene_synonym TNFSF11 8600
Homo sapiens Primates EGF EGF ncbigene_symbol EGF 1950
Homo sapiens Primates IL-1 IL-1 ncbigene_synonym IL1B 3553
Homo sapiens Primates NGF NGF ncbigene_symbol NGF 4803
Homo sapiens Primates CD40L CD40L ncbigene_synonym CD40LG 959
Homo sapiens Primates BAFF BAFF ncbigene_synonym TNFSF13B 10673
Homo sapiens Primates LTA LTA ncbigene_symbol LTA 4049
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR1 7096
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR2 7097
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR3 7098
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR4 7099
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR5 7100
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR6 10333
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR7 51284
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR8 51311
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR9 54106
Homo sapiens Primates 11.IR/TLR TLR famplex_relations TLR10 81793
Homo sapiens Primates CD4 CD4 ncbigene_symbol CD4 920
Homo sapiens Primates FRAP FRAP ncbigene_synonym MTOR 2475
Homo sapiens Primates PRAP PRAP ncbigene_synonym SKAP2 8935
Homo sapiens Primates PRAP PRAP ncbigene_synonym HSD17B7 51478
Homo sapiens Primates TRAF TRAF famplex_relations TRAF1 7185
Homo sapiens Primates TRAF TRAF famplex_relations TRAF2 7186
Homo sapiens Primates TRAF TRAF famplex_relations TRAF3 7187
Homo sapiens Primates TRAF TRAF famplex_relations TRAF4 9618
Homo sapiens Primates TRAF TRAF famplex_relations TRAF5 7188
Homo sapiens Primates TRAF TRAF famplex_relations TRAF6 7189
Homo sapiens Primates TRAF TRAF famplex_relations TRAF7 84231
Homo sapiens Primates Ras RAS famplex_relations KRAS 3845
Homo sapiens Primates Ras RAS famplex_relations HRAS 3265
Homo sapiens Primates Ras RAS famplex_relations NRAS 4893
Homo sapiens Primates RIP RIP ncbigene_synonym AGFG1 3267
Homo sapiens Primates RIP RIP ncbigene_synonym RIPK1 8737
Homo sapiens Primates RIP RIP ncbigene_synonym DCAF1 9730
Homo sapiens Primates RIP RIP ncbigene_synonym RPAIN 84268
Homo sapiens Primates IRAK IRAK ncbigene_synonym IRAK1 3654
Homo sapiens Primates IRAKM IRAKM ncbigene_synonym IRAK3 11213
Homo sapiens Primates RAK RAK ncbigene_synonym ADAM10 102
Homo sapiens Primates RAK RAK ncbigene_synonym FRK 2444
Homo sapiens Primates A20 A20 ncbigene_synonym TNFAIP3 7128
Homo sapiens Primates A20 A20 ncbigene_synonym IGKV1-27 28935
Homo sapiens Primates MEKK MEKK ncbigene_synonym MAP3K1 4214
Homo sapiens Primates NIK NIK ncbigene_synonym MAP3K14 9020
Homo sapiens Primates NIK NIK ncbigene_synonym MAP4K4 9448
Homo sapiens Primates PAR PAR ncbigene_synonym NR1I2 8856
Homo sapiens Primates PAR PAR ncbigene_synonym JTB 10899
Homo sapiens Primates (RAF RAF ncbigene_synonym ZHX2 22882
Homo sapiens Primates (RAF RAF famplex_relations ARAF 369
Homo sapiens Primates (RAF RAF famplex_relations BRAF 673
Homo sapiens Primates (RAF RAF famplex_relations RAF1 5894
Homo sapiens Primates Cot COT ncbigene_synonym MAP3K8 1326
Homo sapiens Primates Cot COT ncbigene_synonym CROT 54677
Homo sapiens Primates NF-KB2 NF-KB2 ncbigene_synonym NFKB2 4791
Homo sapiens Primates p50 P50 ncbigene_synonym CD40 958
Homo sapiens Primates p50 P50 ncbigene_synonym ARHGEF7 8874
Homo sapiens Primates p50 P50 ncbigene_synonym ASCC1 51008
Homo sapiens Primates p50 P50 ncbigene_synonym H3P40 115482723
Homo sapiens Primates RelB RELB ncbigene_symbol RELB 5971
Homo sapiens Primates RelA RELA ncbigene_symbol RELA 5970
Homo sapiens Primates p65 P65 ncbigene_synonym SYT1 6857
Homo sapiens Primates p65 P65 ncbigene_synonym GORASP1 64689
Homo sapiens Primates p65 P65 ncbigene_synonym WNK1 65125
Homo sapiens Primates Rel REL ncbigene_symbol REL 5966
Homo sapiens Primates PKA PKA famplex_relations PRKAR1A 5573
Homo sapiens Primates PKA PKA famplex_relations PRKAR1B 5575
Homo sapiens Primates PKA PKA famplex_relations PRKAR2A 5576
Homo sapiens Primates PKA PKA famplex_relations PRKAR2B 5577
Homo sapiens Primates PKA PKA famplex_relations PRKACA 5566
Homo sapiens Primates PKA PKA famplex_relations PRKACB 5567
Homo sapiens Primates PKA PKA famplex_relations PRKACG 5568
Homo sapiens Primates NAK NAK ncbigene_synonym TBK1 29110
Homo sapiens Primates AB AB ncbigene_synonym APP 351
Homo sapiens Primates AB AB ncbigene_synonym SUCLA2 8803
Homo sapiens Primates İKKA IKKA ncbigene_synonym CHUK 1147
Homo sapiens Primates CHP/p00 CHP ncbigene_synonym CHP1 11261
Homo sapiens Primates CHP/p00 CHP ncbigene_synonym RHOV 171177
Homo sapiens Primates pes/RelA PES ncbigene_synonym PES1 23481
Homo sapiens Primates All ALL ncbigene_synonym BCR 613
Homo sapiens Primates All A11 ncbigene_synonym IGKV3D-20 28874

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Cancer NA
Rheumatoid arthritis NA