Ergosterol synthesis pathway and known inhibitors of the pathway enzymes
Ergosterol synthesis pathway and known inhibitors of the pathway enzymes.
Publication
Silicon Incorporated Morpholine Antifungals: Design, Synthesis, and Biological Evaluation. (2015) Gorakhnath R. Jachak, et al. ACS Med Chem Lett. 2015 Nov 12;6(11):1111-1116. Figure: F1.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| 4,4-dimethylzymosterol | 14-demethyllanosterol | mesh:C013499 | 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol | chebi:18364 |
| Ignosterol | NA | mesh:C015291 | ||
| Naftifine | NA | mesh:C029178 | ||
| Fecosterol | fecosterol | mesh:C039241 | fecosterol | chebi:17038 |
| Fenpropimorph | fenpropimorph | mesh:C050435 | fenpropimorph | chebi:50145 |
| Episterol | episterol | mesh:C060242 | episterol | chebi:23929 |
| Fenpropidin | NA | mesh:C063198 | ||
| 4,4-dimethylcholesta-8,14,24trienol | NA | mesh:C100324 | ||
| Allylamines | NA | mesh:D000499 | ||
| Azoles | NA | mesh:D001393 | ||
| Ergosterol | Ergosterol | mesh:D004875 | ergosterol | chebi:16933 |
| Lanosterol | Lanosterol | mesh:D007810 | lanosterol | chebi:16521 |
| Squalene | Squalene | mesh:D013185 | squalene | chebi:15440 |
| Sterol | Sterols | mesh:D013261 | sterol | chebi:15889 |
| Fluconazole | Fluconazole | mesh:D015725 | fluconazole | chebi:46081 |
| Voriconazole | Voriconazole | mesh:D065819 | voriconazole | chebi:10023 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|