How p-CREB acts as a common downstream effector for multiple signaling pathways that regulate BCRP mRNA expression Xie, et.al
Schematic of how p-CREB acts as a common downstream effector for multiple signaling pathways that regulate BCRP mRNA expression Xie, et.al.
Publication
Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2 transcription in human cancer cells. () Yi Xie, et al. Biochim Biophys Acta. ;1849(3):317-327. Figure: F9.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Mus musculus | Rodents | EGF | EGF | ncbigene_symbol | Egf | 13645 |
| Mus musculus | Rodents | EGFR | EGFR | ncbigene_symbol | Egfr | 13649 |
| Mus musculus | Rodents | PI3K/AKT++ | PI3K | ncbigene_synonym | Pik3r1 | 18708 |
| Mus musculus | Rodents | AKT | AKT | ncbigene_synonym | Akt1 | 11651 |
| Mus musculus | Rodents | RAS/MAPK | RAS | ncbigene_symbol | ras | 19412 |
| Mus musculus | Rodents | RAS/MAPK | RAS | ncbigene_synonym | Hras | 15461 |
| Mus musculus | Rodents | RAS/MAPK | RAS | ncbigene_synonym | Kras | 16653 |
| Mus musculus | Rodents | RAS/MAPK | RAS | ncbigene_synonym | Rem1 | 19700 |
| Mus musculus | Rodents | CREB | CREB | ncbigene_synonym | Creb1 | 12912 |
| Mus musculus | Rodents | CRTC2 | CRTC2 | ncbigene_symbol | Crtc2 | 74343 |
| Mus musculus | Rodents | BCRP | BCRP | ncbigene_synonym | Abcg2 | 26357 |
| Bos taurus | Mammals | EGF | EGF | ncbigene_symbol | EGF | 530315 |
| Bos taurus | Mammals | EGFR | EGFR | ncbigene_symbol | EGFR | 407217 |
| Bos taurus | Mammals | PI3K/AKT++ | PI3K | ncbigene_synonym | PIK3CB | 517948 |
| Bos taurus | Mammals | AKT | AKT | ncbigene_synonym | AKT1 | 280991 |
| Bos taurus | Mammals | CREB | CREB | ncbigene_synonym | CREB1 | 281713 |
| Bos taurus | Mammals | CRTC2 | CRTC2 | ncbigene_symbol | CRTC2 | 540959 |
| Bos taurus | Mammals | ABCG2 | ABCG2 | ncbigene_symbol | ABCG2 | 536203 |
| Homo sapiens | Primates | EGF | EGF | ncbigene_symbol | EGF | 1950 |
| Homo sapiens | Primates | EGFR | EGFR | ncbigene_symbol | EGFR | 1956 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | ncbigene_synonym | PIK3CA | 5290 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | ncbigene_synonym | PIK3CB | 5291 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | ncbigene_synonym | PIK3CD | 5293 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | ncbigene_synonym | PIK3CG | 5294 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | famplex_relations | PIK3R3 | 8503 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | famplex_relations | PIK3R4 | 30849 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | famplex_relations | PIK3R5 | 23533 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | famplex_relations | PIK3R6 | 146850 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | famplex_relations | PIK3R1 | 5295 |
| Homo sapiens | Primates | PI3K/AKT++ | PI3K | famplex_relations | PIK3R2 | 5296 |
| Homo sapiens | Primates | AKT | AKT | ncbigene_synonym | AKT1 | 207 |
| Homo sapiens | Primates | AKT | AKT | famplex_relations | AKT2 | 208 |
| Homo sapiens | Primates | AKT | AKT | famplex_relations | AKT3 | 10000 |
| Homo sapiens | Primates | ATP | ATP | ncbigene_synonym | ATP8A2 | 51761 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK1 | 5594 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK3 | 5595 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK11 | 5600 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK12 | 6300 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK13 | 5603 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK14 | 1432 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK8 | 5599 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK9 | 5601 |
| Homo sapiens | Primates | RAS/MAPK | MAPK | famplex_relations | MAPK10 | 5602 |
| Homo sapiens | Primates | RAS/MAPK | RAS | famplex_relations | KRAS | 3845 |
| Homo sapiens | Primates | RAS/MAPK | RAS | famplex_relations | HRAS | 3265 |
| Homo sapiens | Primates | RAS/MAPK | RAS | famplex_relations | NRAS | 4893 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKAR1A | 5573 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKAR1B | 5575 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKAR2A | 5576 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKAR2B | 5577 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKACA | 5566 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKACB | 5567 |
| Homo sapiens | Primates | PKA | PKA | famplex_relations | PRKACG | 5568 |
| Homo sapiens | Primates | CREB | CREB | ncbigene_synonym | CREB1 | 1385 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | CREB3 | 10488 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | CREB5 | 9586 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | CREB3L1 | 90993 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | CREB3L2 | 64764 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | CREB3L3 | 84699 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | CREB3L4 | 148327 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | CREM | 1390 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | ATF1 | 466 |
| Homo sapiens | Primates | CREB | CREB | famplex_relations | ATF2 | 1386 |
| Homo sapiens | Primates | AMPK | AMPK | ncbigene_synonym | PRKAA1 | 5562 |
| Homo sapiens | Primates | AMPK | AMPK | ncbigene_synonym | PRKAA2 | 5563 |
| Homo sapiens | Primates | AMPK | AMPK | ncbigene_synonym | PRKAB1 | 5564 |
| Homo sapiens | Primates | AMPK | AMPK | famplex_relations | PRKAB2 | 5565 |
| Homo sapiens | Primates | AMPK | AMPK | famplex_relations | PRKAG1 | 5571 |
| Homo sapiens | Primates | AMPK | AMPK | famplex_relations | PRKAG2 | 51422 |
| Homo sapiens | Primates | AMPK | AMPK | famplex_relations | PRKAG3 | 53632 |
| Homo sapiens | Primates | CRTC2 | CRTC2 | ncbigene_symbol | CRTC2 | 200186 |
| Homo sapiens | Primates | BCRP | BCRP | ncbigene_synonym | ABCG2 | 9429 |
| Oryctolagus cuniculus | Mammals | EGF | EGF | ncbigene_symbol | EGF | 100008808 |
| Oryctolagus cuniculus | Mammals | EGFR | EGFR | ncbigene_symbol | EGFR | 100008806 |
| Oryctolagus cuniculus | Mammals | CRTC2 | CRTC2 | ncbigene_symbol | CRTC2 | 100358960 |
| Drosophila melanogaster | Invertebrates | EGF | EGF | ncbigene_synonym | Egfr | 37455 |
| Drosophila melanogaster | Invertebrates | PI3K/AKT++ | PI3K | ncbigene_synonym | Pi3K21B | 33203 |
| Drosophila melanogaster | Invertebrates | PI3K/AKT++ | PI3K | ncbigene_synonym | Pi3K59F | 37733 |
| Drosophila melanogaster | Invertebrates | PI3K/AKT++ | PI3K | ncbigene_synonym | Pi3K68D | 39329 |
| Drosophila melanogaster | Invertebrates | PI3K/AKT++ | PI3K | ncbigene_synonym | Pi3K92E | 42446 |
| Drosophila melanogaster | Invertebrates | AKT | AKT | ncbigene_symbol | Akt | 41957 |
| Drosophila melanogaster | Invertebrates | ATP | ATP | ncbigene_synonym | ATPsynbeta | 43829 |
| Drosophila melanogaster | Invertebrates | ATP | ATP | ncbigene_synonym | Atpalpha | 48971 |
| Drosophila melanogaster | Invertebrates | RAS/MAPK | MAPK | ncbigene_synonym | MKP-4 | 32963 |
| Drosophila melanogaster | Invertebrates | RAS/MAPK | MAPK | ncbigene_synonym | p38b | 34780 |
| Drosophila melanogaster | Invertebrates | RAS/MAPK | MAPK | ncbigene_synonym | rl | 3354888 |
| Drosophila melanogaster | Invertebrates | RAS/MAPK | RAS | ncbigene_symbol | ras | 43873 |
| Drosophila melanogaster | Invertebrates | RAS/MAPK | RAS | ncbigene_synonym | Ras64B | 38494 |
| Drosophila melanogaster | Invertebrates | RAS/MAPK | RAS | ncbigene_synonym | Ras85D | 41140 |
| Drosophila melanogaster | Invertebrates | PKA | PKA | ncbigene_synonym | Pka-C1 | 34284 |
| Drosophila melanogaster | Invertebrates | PKA | PKA | ncbigene_synonym | Pka-R2 | 36041 |
| Drosophila melanogaster | Invertebrates | PKA | PKA | ncbigene_synonym | Pka-C3 | 39733 |
| Drosophila melanogaster | Invertebrates | PKA | PKA | ncbigene_synonym | Pka-R1 | 40305 |
| Drosophila melanogaster | Invertebrates | PKA | PKA | ncbigene_synonym | Pka-C2 | 43644 |
| Drosophila melanogaster | Invertebrates | CREB | CREB | ncbigene_synonym | CrebB | 32817 |
| Drosophila melanogaster | Invertebrates | CREB | CREB | ncbigene_synonym | CrebA | 39682 |
| Drosophila melanogaster | Invertebrates | AMPK | AMPK | ncbigene_synonym | SNF4Agamma | 42515 |
| Drosophila melanogaster | Invertebrates | AMPK | AMPK | ncbigene_synonym | AMPKalpha | 43904 |
| Danio rerio | Vertebrates | EGF | EGF | ncbigene_symbol | egf | 403045 |
| Danio rerio | Vertebrates | EGF | EGF | ncbigene_synonym | celsr1a | 368436 |
| Danio rerio | Vertebrates | EGFR | EGFR | ncbigene_synonym | egfra | 378478 |
| Danio rerio | Vertebrates | RAS/MAPK | RAS | ncbigene_synonym | rab1ab | 368883 |
| Danio rerio | Vertebrates | CRTC2 | CRTC2 | ncbigene_symbol | crtc2 | 799532 |
| Danio rerio | Vertebrates | receptor/ | RECEPTOR | ncbigene_synonym | kita | 30256 |
| Danio rerio | Vertebrates | receptor/ | RECEPTOR | ncbigene_synonym | ngfra | 100535003 |
| Word | Match | MeSH | Name | ChEBI |
|---|
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|---|---|---|---|
| Cancer | NA |