Wood-Ljungdahl pathway and pathways for acetate and ethanol formation
Wood-Ljungdahl pathway and pathways for acetate and ethanol formation. (A) Shown is the detailed representation of the Wood-Ljungdahl pathway explicitly summarizing the reducing equivalents required for carbon fixation. (B) Pathway showing acetate formation and ethanol formation from acetyl-coA. Reaction abbreviations: FDH7 (formate dehydrogenase), FTHFLi (formate-tetrahydrofolate ligase), MTHFC (methenyltetrahydrofolate cyclohydrolase), MTHFD (methylenetetrahydrofolate dehydrogenase (NADP)), MTHFR5 (5,10-methylenetetrahydrofolate reductase (Ferredoxin) Electron bifurcating), METR (Methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase), CODH_ACS (CODH/Acetyl-CoA synthase), PTAr (phospotransacetylase), ACKr (acetate kinase), ACALD (acetaldehyde dehydrogenase), ALCD2x (ethanol dehydrogenase). Yellow nodes indicate the oxidized form of reducing equivalents and blue nodes indicate the reduced form.
Publication
Characterizing acetogenic metabolism using a genome-scale metabolic reconstruction of Clostridium ljungdahlii. (2013) Harish Nagarajan, et al. Microb Cell Fact. 2013;12:118-118. Figure: F4.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Drosophila melanogaster | Invertebrates | adp | ADP | ncbigene_symbol | adp | 37073 |
| Drosophila melanogaster | Invertebrates | atp | ATP | ncbigene_synonym | ATPsynbeta | 43829 |
| Drosophila melanogaster | Invertebrates | atp | ATP | ncbigene_synonym | Atpalpha | 48971 |
| Drosophila melanogaster | Invertebrates | pi | PI | ncbigene_symbol | pi | 5656965 |
| Drosophila melanogaster | Invertebrates | coa | COA | ncbigene_symbol | Coa | 248135 |
| Drosophila melanogaster | Invertebrates | MTHFD | MTHFD | ncbigene_synonym | pug | 41279 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | CkIIbeta | 32132 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Andorra | 32798 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Anp | 43595 |
| Drosophila melanogaster | Invertebrates | and | AND | ncbigene_synonym | Acam | 44913 |
| Drosophila melanogaster | Invertebrates | lac | LAC | ncbigene_symbol | Lac | 36363 |
| Drosophila melanogaster | Invertebrates | lac | LAC | ncbigene_synonym | lacquered | 44521 |
| Homo sapiens | Primates | adp | ADP | ncbigene_synonym | WDTC1 | 23038 |
| Homo sapiens | Primates | atp | ATP | ncbigene_synonym | ATP8A2 | 51761 |
| Homo sapiens | Primates | 10fthf | 10FTHF | ncbigene_synonym | ALDH1L1 | 10840 |
| Homo sapiens | Primates | MTHFC | MTHFC | ncbigene_synonym | MTHFD1 | 4522 |
| Homo sapiens | Primates | nadph | NADPH | ncbigene_synonym | DECR1 | 1666 |
| Homo sapiens | Primates | fix | FIX | ncbigene_synonym | F9 | 2158 |
| Homo sapiens | Primates | fix | FIX | ncbigene_synonym | AK3 | 50808 |
| Homo sapiens | Primates | PTAR | PTAR | ncbigene_synonym | CLDN14-AS1 | 105369301 |
| Homo sapiens | Primates | lac | LAC | ncbigene_synonym | LCT | 3938 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| acetate | Acetates | mesh:D000085 | acetate ester | chebi:47622 |
| ethanol | Ethanol | mesh:D000431 | ethanol | chebi:16236 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|