The urea cycle
The urea cycle. The urea cycle is a pathway of cytosolic and mitochondrial proteins involved in the conversion of ammonia (NH4) to urea for excretion via the kidneys. The enzymes in the pathway are as follows: carbamoylphosphate synthetase (CPS1), ornithine transcarbamylase (OTC); argininosuccinic acid synthase (ASS); argininosuccinic acid lyase (ASL); arginase I (ARG); nitric oxide synthase (NOS). Pearl [].
Publication
Metabolic Causes of Epileptic Encephalopathy. (2013) Joe Yuezhou Yu, et al. Epilepsy Res Treat. 2013;2013:124934. Figure: F6.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | ATP | ATP | ncbigene_synonym | ATP8A2 | 51761 |
| Homo sapiens | Primates | OTC. | OTC | ncbigene_symbol | OTC | 5009 |
| Homo sapiens | Primates | ASS | ASS | ncbigene_synonym | ASS1 | 445 |
| Homo sapiens | Primates | NOS | NOS | ncbigene_synonym | NOS1 | 4842 |
| Homo sapiens | Primates | NOS | NOS | ncbigene_synonym | NOS2 | 4843 |
| Homo sapiens | Primates | NOS | NOS | famplex_relations | NOS3 | 4846 |
| Homo sapiens | Primates | ASL | ASL | ncbigene_symbol | ASL | 435 |
| Homo sapiens | Primates | ASL | ASL | ncbigene_synonym | ADSL | 158 |
| Homo sapiens | Primates | ARG | ARG | ncbigene_synonym | ABL2 | 27 |
| Homo sapiens | Primates | ARG | ARG | ncbigene_synonym | RERE | 473 |
| Mus musculus | Rodents | OTC. | OTC | ncbigene_symbol | Otc | 18416 |
| Mus musculus | Rodents | ASS | ASS | ncbigene_synonym | Ass1 | 11898 |
| Mus musculus | Rodents | NOS | NOS | ncbigene_synonym | Nos1 | 18125 |
| Mus musculus | Rodents | ASL | ASL | ncbigene_symbol | Asl | 109900 |
| Mus musculus | Rodents | ASL | ASL | ncbigene_synonym | Adsl | 11564 |
| Mus musculus | Rodents | ARG | ARG | ncbigene_synonym | Abl2 | 11352 |
| Mus musculus | Rodents | ARG | ARG | ncbigene_synonym | Rere | 68703 |
| Mus musculus | Rodents | ARG | ARG | ncbigene_synonym | Albfm1 | 622307 |
| Drosophila melanogaster | Invertebrates | ATP | ATP | ncbigene_synonym | ATPsynbeta | 43829 |
| Drosophila melanogaster | Invertebrates | ATP | ATP | ncbigene_synonym | Atpalpha | 48971 |
| Drosophila melanogaster | Invertebrates | ASS | ASS | ncbigene_symbol | Ass | 40812 |
| Drosophila melanogaster | Invertebrates | NOS | NOS | ncbigene_symbol | Nos | 34495 |
| Drosophila melanogaster | Invertebrates | NOS | NOS | ncbigene_symbol | nos | 42297 |
| Drosophila melanogaster | Invertebrates | ASL | ASL | ncbigene_symbol | asl | 40682 |
| Drosophila melanogaster | Invertebrates | ARG | ARG | ncbigene_symbol | arg | 46717 |
| Drosophila melanogaster | Invertebrates | ARG | ARG | ncbigene_synonym | aos | 39833 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| Arginine | Arginine | mesh:D001120 | arginine | chebi:29016 |
| ARG | Arginine | mesh:D001120 | arginine | chebi:29016 |
| Aspartate | NA | mesh:D001224 | ||
| Fumarate | NA | mesh:D005650 | ||
| phosphate | NA | mesh:D010710 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|