Simplified schematic representation of the mammalian target of rapamycin (mTOR) signaling pathway.Notes: Red, pathway inhibitor; Green, pathway activator; Blue, mTOR complex protein.Abbreviation: NOS, not otherwise specified

Simplified schematic representation of the mammalian target of rapamycin (mTOR) signaling pathway.Notes: Red, pathway inhibitor; Green, pathway activator; Blue, mTOR complex protein.Abbreviation: NOS, not otherwise specified.
Simplified schematic representation of the mammalian target of rapamycin (mTOR) signaling pathway.Notes: Red, pathway inhibitor; Green, pathway activator; Blue, mTOR complex protein.Abbreviation: NOS, not otherwise specified
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Publication

Treating metastatic soft-tissue or bone sarcomas – potential role of ridaforolimus. (2012) Vicki L Keedy. Onco Targets Ther. 2012;5:153-160. Figure: F1.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Drosophila melanogaster Invertebrates PI3K PI3K ncbigene_synonym Pi3K21B 33203
Drosophila melanogaster Invertebrates PI3K PI3K ncbigene_synonym Pi3K59F 37733
Drosophila melanogaster Invertebrates PI3K PI3K ncbigene_synonym Pi3K68D 39329
Drosophila melanogaster Invertebrates PI3K PI3K ncbigene_synonym Pi3K92E 42446
Drosophila melanogaster Invertebrates IRS IRS ncbigene_synonym IRSp53 39258
Drosophila melanogaster Invertebrates IRS IRS ncbigene_synonym IleRS 45785
Drosophila melanogaster Invertebrates IRS IRS ncbigene_synonym chico 64880
Drosophila melanogaster Invertebrates AKT AKT ncbigene_symbol Akt 41957
Drosophila melanogaster Invertebrates Low LOW ncbigene_symbol Low 44325
Drosophila melanogaster Invertebrates LKB1 LKB1 ncbigene_symbol Lkb1 41673
Drosophila melanogaster Invertebrates AMPK AMPK ncbigene_synonym SNF4Agamma 42515
Drosophila melanogaster Invertebrates AMPK AMPK ncbigene_synonym AMPKalpha 43904
Drosophila melanogaster Invertebrates TSC1/2 TSC2 ncbigene_synonym gig 40201
Drosophila melanogaster Invertebrates TSC1/2 TSC1 ncbigene_symbol Tsc1 42862
Drosophila melanogaster Invertebrates PTEN PTEN ncbigene_symbol Pten 43991
Drosophila melanogaster Invertebrates Rheb RHEB ncbigene_symbol Rheb 117332
Drosophila melanogaster Invertebrates RAG RAG ncbigene_symbol rag 252474
Drosophila melanogaster Invertebrates RAG RAG ncbigene_synonym RagA-B 41071
Drosophila melanogaster Invertebrates RAG RAG ncbigene_synonym rags 252475
Drosophila melanogaster Invertebrates Raptor RAPTOR ncbigene_symbol raptor 31543
Drosophila melanogaster Invertebrates Rictor RICTOR ncbigene_symbol rictor 32919
Drosophila melanogaster Invertebrates PRAS40 PRAS40 ncbigene_symbol PRAS40 26067067
Drosophila melanogaster Invertebrates MTOR MTOR ncbigene_symbol Mtor 36264
Drosophila melanogaster Invertebrates MTOR MTOR ncbigene_synonym Tor 47396
Drosophila melanogaster Invertebrates 4E-BP 4E-BP ncbigene_synonym Thor 33569
Drosophila melanogaster Invertebrates Rho RHO ncbigene_symbol rho 38168
Drosophila melanogaster Invertebrates Rho RHO ncbigene_synonym Bx 32846
Drosophila melanogaster Invertebrates Rho RHO ncbigene_synonym Rho1 36775
Drosophila melanogaster Invertebrates Rho RHO ncbigene_synonym Lcp65Ab1 48382
Drosophila melanogaster Invertebrates PKC PKC ncbigene_synonym inaC 36897
Drosophila melanogaster Invertebrates PKC PKC ncbigene_synonym Pkc98E 43428
Drosophila melanogaster Invertebrates PKC PKC ncbigene_synonym aPKC 47594
Drosophila melanogaster Invertebrates PKC PKC ncbigene_synonym Pkc53E 48311
Drosophila melanogaster Invertebrates S6K S6K ncbigene_symbol S6k 38654
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CA 5290
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CB 5291
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CD 5293
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CG 5294
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R3 8503
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R4 30849
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R5 23533
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R6 146850
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R1 5295
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R2 5296
Homo sapiens Primates IRS IRS ncbigene_synonym IARS1 3376
Homo sapiens Primates IRS IRS famplex_relations IRS1 3667
Homo sapiens Primates IRS IRS famplex_relations IRS2 8660
Homo sapiens Primates IRS IRS famplex_relations IRS4 8471
Homo sapiens Primates AKT AKT ncbigene_synonym AKT1 207
Homo sapiens Primates AKT AKT famplex_relations AKT2 208
Homo sapiens Primates AKT AKT famplex_relations AKT3 10000
Homo sapiens Primates LKB1 LKB1 ncbigene_synonym STK11 6794
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAA1 5562
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAA2 5563
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAB1 5564
Homo sapiens Primates AMPK AMPK famplex_relations PRKAB2 5565
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG1 5571
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG2 51422
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG3 53632
Homo sapiens Primates TSC1/2 TSC2 ncbigene_symbol TSC2 7249
Homo sapiens Primates TSC1/2 TSC1 ncbigene_symbol TSC1 7248
Homo sapiens Primates TSC1/2 TSC1 ncbigene_synonym CCL26 10344
Homo sapiens Primates PTEN PTEN ncbigene_symbol PTEN 5728
Homo sapiens Primates REDD1 REDD1 ncbigene_synonym DDIT4 54541
Homo sapiens Primates Rheb RHEB ncbigene_symbol RHEB 6009
Homo sapiens Primates Rheb RHEB ncbigene_synonym RHEBP1 6008
Homo sapiens Primates Rictor RICTOR ncbigene_symbol RICTOR 253260
Homo sapiens Primates PRAS40 PRAS40 ncbigene_synonym AKT1S1 84335
Homo sapiens Primates MTOR MTOR ncbigene_symbol MTOR 2475
Homo sapiens Primates MLST8 MLST8 ncbigene_symbol MLST8 64223
Homo sapiens Primates Rho RHO ncbigene_symbol RHO 6010
Homo sapiens Primates Rho RHO ncbigene_synonym RHOD 29984
Homo sapiens Primates Rho RHO famplex_relations RHOA 387
Homo sapiens Primates Rho RHO famplex_relations RHOB 388
Homo sapiens Primates Rho RHO famplex_relations RHOC 389
Homo sapiens Primates PKC PKC ncbigene_synonym PRRT2 112476
Homo sapiens Primates PKC PKC famplex_relations PRKCA 5578
Homo sapiens Primates PKC PKC famplex_relations PRKCB 5579
Homo sapiens Primates PKC PKC famplex_relations PRKCD 5580
Homo sapiens Primates PKC PKC famplex_relations PRKCE 5581
Homo sapiens Primates PKC PKC famplex_relations PRKCG 5582
Homo sapiens Primates PKC PKC famplex_relations PRKCH 5583
Homo sapiens Primates PKC PKC famplex_relations PRKCI 5584
Homo sapiens Primates PKC PKC famplex_relations PRKCQ 5588
Homo sapiens Primates PKC PKC famplex_relations PRKCZ 5590
Homo sapiens Primates PKC PKC famplex_relations PRKD3 23683
Homo sapiens Primates S6K S6K ncbigene_synonym RPS6KB1 6198

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Cancer NA