A, Differential expression of proteins involved in glycolysis and TCA cycle
A, Differential expression of proteins involved in glycolysis and TCA cycle. A pathway map was built based on Metacore GeneGO pathway maps of glycolysis and glyconeogenesis. Proteins higher expressed in LS+K cells are shown in red and proteins higher expressed in LS−K cells are shown in blue. Quantified but not significantly differentially expressed proteins (p > 0.05) are shown in gray. B, Peptide ratios for unique peptides of isoforms of hexokinase. Average values from two or three replicates are shown. C, Peptide ratios for unique peptides of subunits of lactate dehydrogenase. Average values from two or three replicates are shown. D, Peptide ratios for unique peptides of isoforms of pyruvate kinase. Average values from two or three replicates are shown.
Publication
Proteomic Cornerstones of Hematopoietic Stem Cell Differentiation: Distinct Signatures of Multipotent Progenitors and Myeloid Committed Cells. (2012) Daniel Klimmeck, et al. Mol Cell Proteomics. 2012 Aug;11(8):286-302. Figure: F4.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Drosophila melanogaster | Invertebrates | MOT | MOT | ncbigene_synonym | neb | 35293 |
| Drosophila melanogaster | Invertebrates | ALDOA | ALDOA | ncbigene_synonym | Ald1 | 43183 |
| Drosophila melanogaster | Invertebrates | dos | DOS | ncbigene_symbol | dos | 38321 |
| Drosophila melanogaster | Invertebrates | dos | DOS | ncbigene_synonym | dc | 44088 |
| Drosophila melanogaster | Invertebrates | PGK | PGK | ncbigene_symbol | Pgk | 33461 |
| Drosophila melanogaster | Invertebrates | ines | INE | ncbigene_symbol | ine | 33659 |
| Drosophila melanogaster | Invertebrates | han | HAN | ncbigene_synonym | Pdfr | 31234 |
| Drosophila melanogaster | Invertebrates | han | HAN | ncbigene_synonym | Gr5a | 44873 |
| Drosophila melanogaster | Invertebrates | PGAM | PGAM | ncbigene_synonym | Pglym78 | 43447 |
| Drosophila melanogaster | Invertebrates | ENO | ENO | ncbigene_symbol | Eno | 33351 |
| Drosophila melanogaster | Invertebrates | PHm | PHM | ncbigene_symbol | phm | 32857 |
| Drosophila melanogaster | Invertebrates | PHm | PHM | ncbigene_symbol | Phm | 37823 |
| Drosophila melanogaster | Invertebrates | PHm | PHM | ncbigene_synonym | ph-p | 31181 |
| Drosophila melanogaster | Invertebrates | PHm | PHM | ncbigene_synonym | Ptth | 33238 |
| Drosophila melanogaster | Invertebrates | PHm | PHM | ncbigene_synonym | ph-d | 44889 |
| Drosophila melanogaster | Invertebrates | DLAT | DLAT | ncbigene_synonym | muc | 34021 |
| Drosophila melanogaster | Invertebrates | CaA | CAA | ncbigene_synonym | tRNA:Gln-TTG-2-1 | 3772230 |
| Drosophila melanogaster | Invertebrates | CaA | CAA | ncbigene_synonym | tRNA:Gln-TTG-1-1 | 3772521 |
| Drosophila melanogaster | Invertebrates | CaA | CAA | ncbigene_synonym | tRNA:Gln-TTG-1-2 | 3772562 |
| Drosophila melanogaster | Invertebrates | CaA | CAA | ncbigene_synonym | tRNA:Gln-TTG-1-3 | 3772589 |
| Drosophila melanogaster | Invertebrates | PCK | PCK | ncbigene_symbol | pck | 31101 |
| Drosophila melanogaster | Invertebrates | DHSA | DHSA | ncbigene_synonym | SdhA | 37228 |
| Drosophila melanogaster | Invertebrates | DHSA | DHSA | ncbigene_synonym | SdhAL | 39348 |
| Drosophila melanogaster | Invertebrates | TEA | TEA | ncbigene_symbol | tea | 36027 |
| Drosophila melanogaster | Invertebrates | PLA | PLA | ncbigene_symbol | Pla | 251551 |
| Drosophila melanogaster | Invertebrates | PLAA | PLAA | ncbigene_synonym | Plap | 43978 |
| Homo sapiens | Primates | GLUT4 | GLUT4 | ncbigene_synonym | SLC2A4 | 6517 |
| Homo sapiens | Primates | MOT | MOT | ncbigene_synonym | HSPA9 | 3313 |
| Homo sapiens | Primates | HXK1 | HXK1 | ncbigene_synonym | HK1 | 3098 |
| Homo sapiens | Primates | ALDO | ALDO | famplex_relations | ALDOA | 226 |
| Homo sapiens | Primates | ALDO | ALDO | famplex_relations | ALDOB | 229 |
| Homo sapiens | Primates | ALDO | ALDO | famplex_relations | ALDOC | 230 |
| Homo sapiens | Primates | dos | DOS | ncbigene_synonym | CBARP | 255057 |
| Homo sapiens | Primates | HXK2 | HXK2 | ncbigene_synonym | HK2 | 3099 |
| Homo sapiens | Primates | PGAM | PGAM | famplex_relations | PGAM1 | 5223 |
| Homo sapiens | Primates | PGAM | PGAM | famplex_relations | PGAM2 | 5224 |
| Homo sapiens | Primates | PEM | PEM | ncbigene_synonym | MUC1 | 4582 |
| Homo sapiens | Primates | ENO | ENO | famplex_relations | ENO1 | 2023 |
| Homo sapiens | Primates | ENO | ENO | famplex_relations | ENO2 | 2026 |
| Homo sapiens | Primates | ENO | ENO | famplex_relations | ENO3 | 2027 |
| Homo sapiens | Primates | ENO | ENO | famplex_relations | ENO4 | 387712 |
| Homo sapiens | Primates | PHm | PHM | ncbigene_synonym | PAM | 5066 |
| Homo sapiens | Primates | HXK3 | HXK3 | ncbigene_synonym | HK3 | 3101 |
| Homo sapiens | Primates | LDHA | LDHA | ncbigene_symbol | LDHA | 3939 |
| Homo sapiens | Primates | LDHD | LDHD | ncbigene_symbol | LDHD | 197257 |
| Homo sapiens | Primates | DLAT | DLAT | ncbigene_symbol | DLAT | 1737 |
| Homo sapiens | Primates | CaA | CAA | ncbigene_synonym | TSHZ1 | 10194 |
| Homo sapiens | Primates | PUMH | PUMH | ncbigene_synonym | PUM1 | 9698 |
| Homo sapiens | Primates | Cae | CAE | ncbigene_synonym | GJA8 | 2703 |
| Homo sapiens | Primates | LDHB | LDHB | ncbigene_symbol | LDHB | 3945 |
| Homo sapiens | Primates | PKM2 | PKM2 | ncbigene_synonym | PKM | 5315 |
| Homo sapiens | Primates | PKM2 | PKM2 | famplex_relations | PKLR | 5313 |
| Homo sapiens | Primates | PLAA | PLAA | ncbigene_symbol | PLAA | 9373 |
| Homo sapiens | Primates | lallalLilu1,anml | ANM1 | ncbigene_synonym | PRMT1 | 3276 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| Succinate | Succinates | mesh:D013386 | succinate | chebi:26806 |
| Lactate | NA | mesh:D019344 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|