This figure illustrates the core TSC-mTor pathway, as discussed in the text

This figure illustrates the core TSC-mTor pathway, as discussed in the text. The green signaling path relates to disease such as the Cowden syndrome, Bannayan Riley Rucvalcaba, Proteus syndrome and Lhermitte-Duclos. The purple signaling cascade relates to disease such as Familial cardiac hypertrophy, the Wolf-Parkinson-White syndrome and the Peutz–Jeghers syndrome. The blue signaling path relates to the tuberous sclerosis complex disease, affecting multi-organs and often leading to neurologic disorders. The red part is active in different types of cancers including ovarian, gastrointestinal, breast, sporadic and gall bladder and non-small cell carcinoma in the lung. A detailed overview about disease relating to this pathway is given in [].

Publication

An Image Driven Systems Biology Approach for Neurodegenerative Disease Studies in the TSC-mTOR Pathway. () Dominik Beck, et al. IEEE NIH Life Sci Syst Appl Workshop. :36-39. Figure: F1. All organisms Drosophila melanogaster Homo sapiens

Disease mentions