Multiple factors and pathways affect insulin-like growth factor 1 (IGF1)-Akt signaling

Multiple factors and pathways affect insulin-like growth factor 1 (IGF1)-Akt signaling. Various factors and pathways affecting the IGF1-Akt pathway are highlighted in red. See text for details.
Multiple factors and pathways affect insulin-like growth factor 1 (IGF1)-Akt signaling
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Publication

Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models. (2011) Stefano Schiaffino, et al. Skelet Muscle. 2011;1:4-4. Figure: F3.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Drosophila melanogaster Invertebrates TNF. TNF ncbigene_synonym egr 36054
Drosophila melanogaster Invertebrates IRS IRS ncbigene_synonym IRSp53 39258
Drosophila melanogaster Invertebrates IRS IRS ncbigene_synonym IleRS 45785
Drosophila melanogaster Invertebrates IRS IRS ncbigene_synonym chico 64880
Drosophila melanogaster Invertebrates JNK JNK ncbigene_synonym bsk 44801
Drosophila melanogaster Invertebrates ILK ILK ncbigene_symbol Ilk 53573
Drosophila melanogaster Invertebrates Integrin INTEGRIN ncbigene_synonym scb 36692
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym egh 31239
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym LanB1 34068
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym betaTub56D 37238
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym mys 44885
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym Prosbeta1 46058
Drosophila melanogaster Invertebrates PI3K PI3K ncbigene_synonym Pi3K21B 33203
Drosophila melanogaster Invertebrates PI3K PI3K ncbigene_synonym Pi3K59F 37733
Drosophila melanogaster Invertebrates PI3K PI3K ncbigene_synonym Pi3K68D 39329
Drosophila melanogaster Invertebrates PI3K PI3K ncbigene_synonym Pi3K92E 42446
Drosophila melanogaster Invertebrates PTEN PTEN ncbigene_symbol Pten 43991
Drosophila melanogaster Invertebrates PDK1 PDK1 ncbigene_symbol Pdk1 38017
Drosophila melanogaster Invertebrates Smad SMAD ncbigene_synonym Smox 31738
Drosophila melanogaster Invertebrates Smad SMAD ncbigene_synonym Mad 33529
Drosophila melanogaster Invertebrates Akt AKT ncbigene_symbol Akt 41957
Drosophila melanogaster Invertebrates PLD1 PLD1 ncbigene_synonym Pld 35554
Drosophila melanogaster Invertebrates MTORC1 MTORC1 ncbigene_synonym Crtc 39970
Drosophila melanogaster Invertebrates Foxo FOXO ncbigene_symbol foxo 41709
Drosophila melanogaster Invertebrates AMPK AMPK ncbigene_synonym SNF4Agamma 42515
Drosophila melanogaster Invertebrates AMPK AMPK ncbigene_synonym AMPKalpha 43904
Drosophila melanogaster Invertebrates NFKB NFKB ncbigene_synonym Dif 35045
Drosophila melanogaster Invertebrates NFKB NFKB ncbigene_synonym dl 35047
Drosophila melanogaster Invertebrates NFKB NFKB ncbigene_synonym Rel 41087
Drosophila melanogaster Invertebrates S6K S6K ncbigene_symbol S6k 38654
Homo sapiens Primates IGF1 IGF1 ncbigene_symbol IGF1 3479
Homo sapiens Primates TNF. TNF ncbigene_symbol TNF 7124
Homo sapiens Primates IRS IRS ncbigene_synonym IARS1 3376
Homo sapiens Primates IRS IRS famplex_relations IRS1 3667
Homo sapiens Primates IRS IRS famplex_relations IRS2 8660
Homo sapiens Primates IRS IRS famplex_relations IRS4 8471
Homo sapiens Primates JNK JNK ncbigene_synonym MAPK8 5599
Homo sapiens Primates JNK JNK famplex_relations MAPK9 5601
Homo sapiens Primates JNK JNK famplex_relations MAPK10 5602
Homo sapiens Primates ILK ILK ncbigene_symbol ILK 3611
Homo sapiens Primates B1 B1 ncbigene_synonym B3GNT2 10678
Homo sapiens Primates B1 B1 ncbigene_synonym B3GNTL1 146712
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CA 5290
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CB 5291
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CD 5293
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CG 5294
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R3 8503
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R4 30849
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R5 23533
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R6 146850
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R1 5295
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R2 5296
Homo sapiens Primates PTEN PTEN ncbigene_symbol PTEN 5728
Homo sapiens Primates PDK1 PDK1 ncbigene_symbol PDK1 5163
Homo sapiens Primates PDK1 PDK1 ncbigene_synonym PDPK1 5170
Homo sapiens Primates Smad SMAD famplex_relations SMAD1 4086
Homo sapiens Primates Smad SMAD famplex_relations SMAD4 4089
Homo sapiens Primates Smad SMAD famplex_relations SMAD5 4090
Homo sapiens Primates Smad SMAD famplex_relations SMAD6 4091
Homo sapiens Primates Smad SMAD famplex_relations SMAD7 4092
Homo sapiens Primates Smad SMAD famplex_relations SMAD9 4093
Homo sapiens Primates Smad SMAD famplex_relations SMAD2 4087
Homo sapiens Primates Smad SMAD famplex_relations SMAD3 4088
Homo sapiens Primates Akt AKT ncbigene_synonym AKT1 207
Homo sapiens Primates Akt AKT famplex_relations AKT2 208
Homo sapiens Primates Akt AKT famplex_relations AKT3 10000
Homo sapiens Primates ActRIIB ACTRIIB ncbigene_synonym ACVR2B 93
Homo sapiens Primates PLD1 PLD1 ncbigene_symbol PLD1 5337
Homo sapiens Primates PLD1 PLD1 ncbigene_synonym PRKCSH 5589
Homo sapiens Primates MTORC1 MTORC1 famplex_relations MTOR 2475
Homo sapiens Primates MTORC1 MTORC1 famplex_relations RPTOR 57521
Homo sapiens Primates Foxo FOXO famplex_relations FOXO1 2308
Homo sapiens Primates Foxo FOXO famplex_relations FOXO3 2309
Homo sapiens Primates Foxo FOXO famplex_relations FOXO4 4303
Homo sapiens Primates Foxo FOXO famplex_relations FOXO6 100132074
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAA1 5562
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAA2 5563
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAB1 5564
Homo sapiens Primates AMPK AMPK famplex_relations PRKAB2 5565
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG1 5571
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG2 51422
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG3 53632
Homo sapiens Primates NFKB NFKB ncbigene_synonym NFKB1 4790
Homo sapiens Primates NFKB NFKB famplex_relations RELA 5970
Homo sapiens Primates NFKB NFKB famplex_relations RELB 5971
Homo sapiens Primates NFKB NFKB famplex_relations REL 5966
Homo sapiens Primates NFKB NFKB famplex_relations NFKB2 4791
Homo sapiens Primates S6K S6K ncbigene_synonym RPS6KB1 6198
Homo sapiens Primates MURF1 MURF1 ncbigene_synonym TRIM63 84676
Homo sapiens Primates TWEAK TWEAK ncbigene_synonym TNFSF12 8742

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Cancer NA