CoQ10 biosynthesis pathway

CoQ10 biosynthesis pathway. CoQ10 is composed of a benzoquinone ring and a decaprenyl side chain. ADCK3 (CABC1) is a kinase that modulate CoQ10synthesis, possibly through phosphorylation of COQ3 []. The function of COQ9 is unknown.
CoQ10 biosynthesis pathway
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Publication

Coenzyme Q and Mitochondrial Disease. () Catarina M. Quinzii, et al. Dev Disabil Res Rev. ;16(2):183-188. Figure: F1.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Mus musculus Rodents PPO PPO ncbigene_synonym Ppox 19044
Mus musculus Rodents PDSS1 PDSS1 ncbigene_symbol Pdss1 56075
Mus musculus Rodents PDSS2 PDSS2 ncbigene_symbol Pdss2 71365
Mus musculus Rodents COQ2 COQ2 ncbigene_symbol Coq2 71883
Mus musculus Rodents OH OH ncbigene_symbol oh 18299
Mus musculus Rodents COQ3 COQ3 ncbigene_symbol Coq3 230027
Mus musculus Rodents SAM SAM ncbigene_synonym Snhg15 100041286
Mus musculus Rodents SAH SAH ncbigene_synonym Acsm3 20216
Mus musculus Rodents CABC1 CABC1 ncbigene_synonym Coq8a 67426
Mus musculus Rodents COQ6 COQ6 ncbigene_symbol Coq6 217707
Mus musculus Rodents COQ5 COQ5 ncbigene_symbol Coq5 52064
Mus musculus Rodents COQ7 COQ7 ncbigene_symbol Coq7 12850
Homo sapiens Primates PPO PPO ncbigene_synonym PPOX 5498
Homo sapiens Primates PDSS1 PDSS1 ncbigene_symbol PDSS1 23590
Homo sapiens Primates PDSS2 PDSS2 ncbigene_symbol PDSS2 57107
Homo sapiens Primates COQ2 COQ2 ncbigene_symbol COQ2 27235
Homo sapiens Primates COQ3 COQ3 ncbigene_symbol COQ3 51805
Homo sapiens Primates SAH SAH ncbigene_synonym ACSM3 6296
Homo sapiens Primates CABC1 CABC1 ncbigene_synonym COQ8A 56997
Homo sapiens Primates COQ6 COQ6 ncbigene_symbol COQ6 51004
Homo sapiens Primates COQ5 COQ5 ncbigene_symbol COQ5 84274
Homo sapiens Primates COQ7 COQ7 ncbigene_symbol COQ7 10229
Caenorhabditis elegans Invertebrates COQ2 COQ2 ncbigene_symbol coq-2 175969
Caenorhabditis elegans Invertebrates COQ3 COQ3 ncbigene_symbol coq-3 178403
Caenorhabditis elegans Invertebrates COQ6 COQ6 ncbigene_symbol coq-6 179316
Caenorhabditis elegans Invertebrates COQ5 COQ5 ncbigene_symbol coq-5 176099
Drosophila melanogaster Invertebrates PPO PPO ncbigene_synonym PPO2 35910
Drosophila melanogaster Invertebrates PPO PPO ncbigene_synonym PPO1 37044
Drosophila melanogaster Invertebrates PPO PPO ncbigene_synonym Ppox 42939
Drosophila melanogaster Invertebrates PPO PPO ncbigene_synonym PPO3 44513
Drosophila melanogaster Invertebrates PDSS2 PDSS2 ncbigene_symbol Pdss2 40323
Drosophila melanogaster Invertebrates COQ2 COQ2 ncbigene_symbol Coq2 40988
Drosophila melanogaster Invertebrates COQ? COQ ncbigene_symbol coq 45984
Drosophila melanogaster Invertebrates COQ3 COQ3 ncbigene_symbol Coq3 35383
Drosophila melanogaster Invertebrates SAM SAM ncbigene_symbol sam 44534
Drosophila melanogaster Invertebrates SAM SAM ncbigene_synonym qkr54B 36966
Drosophila melanogaster Invertebrates SAM SAM ncbigene_synonym sls 44013
Drosophila melanogaster Invertebrates SAM SAM ncbigene_synonym Sam-S 48552
Drosophila melanogaster Invertebrates SAH SAH ncbigene_symbol sah 5658327
Drosophila melanogaster Invertebrates COQ6 COQ6 ncbigene_symbol Coq6 33777
Drosophila melanogaster Invertebrates COQ5 COQ5 ncbigene_symbol Coq5 32272
Drosophila melanogaster Invertebrates COQ7 COQ7 ncbigene_symbol Coq7 44007

Chemical mentions

Word Match MeSH Name ChEBI
Farnesyl pyrophosphate 2-trans,6-trans-farnesyl diphosphate mesh:C004808 farnesyl pyrophosphate chebi:17407

Disease mentions

Word Match MeSH Name DOID
Coenzyme Q10 deficiency disease NA