Update on the regulation of mammalian melanocyte function and skin pigmentation

Various factors that regulate melanocyte function in the skin are shown. Antagonists of receptor binding are shown in red.Adapted from [].
Update on the regulation of mammalian melanocyte function and skin pigmentation
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Publication

Update on the regulation of mammalian melanocyte function and skin pigmentation. () Taisuke Kondo, et al. Expert Rev Dermatol. ;6(1):97-108. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates p53 P53 ncbigene_synonym TP53 7157
Homo sapiens Primates p53 P53 famplex_relations TP63 8626
Homo sapiens Primates p53 P53 famplex_relations TP73 7161
Homo sapiens Primates POMC POMC ncbigene_symbol POMC 5443
Homo sapiens Primates NGF NGF ncbigene_symbol NGF 4803
Homo sapiens Primates NGF-R NGFR ncbigene_symbol NGFR 4804
Homo sapiens Primates GM-CSF GMCSF ncbigene_synonym CSF2 1437
Homo sapiens Primates HGF HGF ncbigene_symbol HGF 3082
Homo sapiens Primates HGF HGF ncbigene_synonym IL6 3569
Homo sapiens Primates HGF HGF ncbigene_synonym SOS1 6654
Homo sapiens Primates KIT KIT ncbigene_symbol KIT 3815
Homo sapiens Primates EDN1 EDN1 ncbigene_symbol EDN1 1906
Homo sapiens Primates EDN1/3 EDN3 ncbigene_symbol EDN3 1908
Homo sapiens Primates GM-CSFR GMCSFR ncbigene_synonym CSF2RA 1438
Homo sapiens Primates EDNRB EDNRB ncbigene_symbol EDNRB 1910
Homo sapiens Primates BFGF BFGF ncbigene_synonym FGF2 2247
Homo sapiens Primates FGFR FGFR famplex_relations FGFR1 2260
Homo sapiens Primates FGFR FGFR famplex_relations FGFR2 2263
Homo sapiens Primates FGFR FGFR famplex_relations FGFR3 2261
Homo sapiens Primates FGFR FGFR famplex_relations FGFR4 2264
Homo sapiens Primates FGFR FGFR famplex_relations FGFRL1 53834
Homo sapiens Primates MC1R MC1R ncbigene_symbol MC1R 4157
Homo sapiens Primates Gsn GSN ncbigene_symbol GSN 2934
Homo sapiens Primates PLC PLC ncbigene_synonym HSPG2 3339
Homo sapiens Primates PLC PLC famplex_relations PLCE1 51196
Homo sapiens Primates PLC PLC famplex_relations PLCZ1 89869
Homo sapiens Primates PLC PLC famplex_relations PLCB1 23236
Homo sapiens Primates PLC PLC famplex_relations PLCB2 5330
Homo sapiens Primates PLC PLC famplex_relations PLCB3 5331
Homo sapiens Primates PLC PLC famplex_relations PLCB4 5332
Homo sapiens Primates PLC PLC famplex_relations PLCD1 5333
Homo sapiens Primates PLC PLC famplex_relations PLCD3 113026
Homo sapiens Primates PLC PLC famplex_relations PLCD4 84812
Homo sapiens Primates PLC PLC famplex_relations PLCG1 5335
Homo sapiens Primates PLC PLC famplex_relations PLCG2 5336
Homo sapiens Primates CAMP/PKA PKA famplex_relations PRKAR1A 5573
Homo sapiens Primates CAMP/PKA PKA famplex_relations PRKAR1B 5575
Homo sapiens Primates CAMP/PKA PKA famplex_relations PRKAR2A 5576
Homo sapiens Primates CAMP/PKA PKA famplex_relations PRKAR2B 5577
Homo sapiens Primates CAMP/PKA PKA famplex_relations PRKACA 5566
Homo sapiens Primates CAMP/PKA PKA famplex_relations PRKACB 5567
Homo sapiens Primates CAMP/PKA PKA famplex_relations PRKACG 5568
Homo sapiens Primates MAP MAP ncbigene_synonym SGSM3 27352
Homo sapiens Primates SOX9 SOX9 ncbigene_symbol SOX9 6662
Homo sapiens Primates CREB CREB ncbigene_synonym CREB1 1385
Homo sapiens Primates CREB CREB famplex_relations CREB3 10488
Homo sapiens Primates CREB CREB famplex_relations CREB5 9586
Homo sapiens Primates CREB CREB famplex_relations CREB3L1 90993
Homo sapiens Primates CREB CREB famplex_relations CREB3L2 64764
Homo sapiens Primates CREB CREB famplex_relations CREB3L3 84699
Homo sapiens Primates CREB CREB famplex_relations CREB3L4 148327
Homo sapiens Primates CREB CREB famplex_relations CREM 1390
Homo sapiens Primates CREB CREB famplex_relations ATF1 466
Homo sapiens Primates CREB CREB famplex_relations ATF2 1386
Homo sapiens Primates MITF MITF ncbigene_symbol MITF 4286
Homo sapiens Primates MelanogenicTYR,TYRP1, TYRP1 ncbigene_symbol TYRP1 7306
Homo sapiens Primates DCT DCT ncbigene_symbol DCT 1638
Homo sapiens Primates WNT WNT famplex_relations WNT1 7471
Homo sapiens Primates WNT WNT famplex_relations WNT2 7472
Homo sapiens Primates WNT WNT famplex_relations WNT2B 7482
Homo sapiens Primates WNT WNT famplex_relations WNT3 7473
Homo sapiens Primates WNT WNT famplex_relations WNT3A 89780
Homo sapiens Primates WNT WNT famplex_relations WNT4 54361
Homo sapiens Primates WNT WNT famplex_relations WNT6 7475
Homo sapiens Primates WNT WNT famplex_relations WNT7A 7476
Homo sapiens Primates WNT WNT famplex_relations WNT7B 7477
Homo sapiens Primates WNT WNT famplex_relations WNT8A 7478
Homo sapiens Primates WNT WNT famplex_relations WNT8B 7479
Homo sapiens Primates WNT WNT famplex_relations WNT9A 7483
Homo sapiens Primates WNT WNT famplex_relations WNT9B 7484
Homo sapiens Primates WNT WNT famplex_relations WNT10A 80326
Homo sapiens Primates WNT WNT famplex_relations WNT10B 7480
Homo sapiens Primates WNT WNT famplex_relations WNT11 7481
Homo sapiens Primates WNT WNT famplex_relations WNT16 51384
Homo sapiens Primates WNT WNT famplex_relations WNT5A 7474
Homo sapiens Primates WNT WNT famplex_relations WNT5B 81029
Homo sapiens Primates LRP LRP ncbigene_synonym RPSA 3921
Homo sapiens Primates LRP LRP ncbigene_synonym LRP1 4035
Homo sapiens Primates LRP LRP ncbigene_synonym PTPRA 5786
Homo sapiens Primates LRP LRP ncbigene_synonym MVP 9961
Homo sapiens Primates Frizzled FZD famplex_relations FZD1 8321
Homo sapiens Primates Frizzled FZD famplex_relations FZD10 11211
Homo sapiens Primates Frizzled FZD famplex_relations FZD2 2535
Homo sapiens Primates Frizzled FZD famplex_relations FZD3 7976
Homo sapiens Primates Frizzled FZD famplex_relations FZD4 8322
Homo sapiens Primates Frizzled FZD famplex_relations FZD5 7855
Homo sapiens Primates Frizzled FZD famplex_relations FZD6 8323
Homo sapiens Primates Frizzled FZD famplex_relations FZD7 8324
Homo sapiens Primates Frizzled FZD famplex_relations FZD8 8325
Homo sapiens Primates Frizzled FZD famplex_relations FZD9 8326
Homo sapiens Primates H2R H2R ncbigene_synonym HRH2 3274
Homo sapiens Primates NRG1 NRG1 ncbigene_symbol NRG1 3084
Homo sapiens Primates Mast MAST ncbigene_synonym SPACA9 11092
Homo sapiens Primates Mast MAST ncbigene_synonym SPG21 51324

Chemical mentions

Word Match MeSH Name ChEBI
Histamine Histamine mesh:D006632 histamine chebi:18295
TYR Tyrosine mesh:D014443 L-tyrosine chebi:17895

Disease mentions

Word Match MeSH Name DOID
Melanoma NA