Sterol biosynthetic pathway in Leishmania
Sterol biosynthetic pathway in Leishmania. The pathway shows the important steps and the enzymes involved in sterol biosynthesis. The final product in trypanosomatids is ergosterol as opposed to cholesterol in mammalian cells
Publication
Drug targets in Leishmania. (2010) Bhavna Chawla, et al. J Parasit Dis. 2010 Apr;34(1):1-13. Figure: F1.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| 2,3-oxidosqualene | NA | mesh:C002821 | ||
| 3-hydroxy-3-methyl-glutaryl-CoA | glutaryl-CoA | mesh:C015901 | glutaryl-coenzyme A | chebi:15524 |
| Ergosterol | Ergosterol | mesh:D004875 | ergosterol | chebi:16933 |
| Lanosterol | Lanosterol | mesh:D007810 | lanosterol | chebi:16521 |
| Mevalonate | NA | mesh:D008798 | ||
| Squalene | Squalene | mesh:D013185 | squalene | chebi:15440 |
| Sterol | Sterols | mesh:D013261 | sterol | chebi:15889 |
| Isoprenoid | terpene | mesh:D013729 | Terpenes | chebi:35186 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|