Differentially expressed genes in the MICs as compared to NSPCs

Ingenuity Pathways Analysis of the differentially expressed genes in the MICs as compared to NSPCs. A, IPA analysis associated the differential expression of MICs as related to Cancer, Cellular Growth and Proliferation, Connective Tissue Development and Function. Genes shaded red are identified as upregulated and, green, as downregulated. B, the functional analysis identified top canonical pathways, and C, diseases most significant with the differentially expressed genes. For example, Canonical pathways analysis identified the Wnt/β-catenin pathway as being the top pathway associated with the differentially expressed gene set.
Differentially expressed genes in the MICs as compared to NSPCs
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Publication

Isolation and Characterization of a Population of Stem-like Progenitor Cells From an Atypical Meningioma. () Prakash Rath, et al. Exp Mol Pathol. ;90(2):179-188. Figure: F6.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates Wnt WNT famplex_relations WNT1 7471
Homo sapiens Primates Wnt WNT famplex_relations WNT2 7472
Homo sapiens Primates Wnt WNT famplex_relations WNT2B 7482
Homo sapiens Primates Wnt WNT famplex_relations WNT3 7473
Homo sapiens Primates Wnt WNT famplex_relations WNT3A 89780
Homo sapiens Primates Wnt WNT famplex_relations WNT4 54361
Homo sapiens Primates Wnt WNT famplex_relations WNT6 7475
Homo sapiens Primates Wnt WNT famplex_relations WNT7A 7476
Homo sapiens Primates Wnt WNT famplex_relations WNT7B 7477
Homo sapiens Primates Wnt WNT famplex_relations WNT8A 7478
Homo sapiens Primates Wnt WNT famplex_relations WNT8B 7479
Homo sapiens Primates Wnt WNT famplex_relations WNT9A 7483
Homo sapiens Primates Wnt WNT famplex_relations WNT9B 7484
Homo sapiens Primates Wnt WNT famplex_relations WNT10A 80326
Homo sapiens Primates Wnt WNT famplex_relations WNT10B 7480
Homo sapiens Primates Wnt WNT famplex_relations WNT11 7481
Homo sapiens Primates Wnt WNT famplex_relations WNT16 51384
Homo sapiens Primates Wnt WNT famplex_relations WNT5A 7474
Homo sapiens Primates Wnt WNT famplex_relations WNT5B 81029
Homo sapiens Primates B-catenin CTNNB1 ncbigene_symbol CTNNB1 1499
Homo sapiens Primates TGFB3 TGFB3 ncbigene_symbol TGFB3 7043
Homo sapiens Primates TÍMP1 TIMP1 ncbigene_symbol TIMP1 7076
Homo sapiens Primates SPARC SPARC ncbigene_symbol SPARC 6678
Homo sapiens Primates PTEN PTEN ncbigene_symbol PTEN 5728
Homo sapiens Primates ERK ERK ncbigene_synonym EPHB2 2048
Homo sapiens Primates ERK ERK ncbigene_synonym MAPK1 5594
Homo sapiens Primates ERK ERK famplex_relations MAPK3 5595
Homo sapiens Primates MAPK MAPK famplex_relations MAPK11 5600
Homo sapiens Primates MAPK MAPK famplex_relations MAPK12 6300
Homo sapiens Primates MAPK MAPK famplex_relations MAPK13 5603
Homo sapiens Primates MAPK MAPK famplex_relations MAPK14 1432
Homo sapiens Primates MAPK MAPK famplex_relations MAPK8 5599
Homo sapiens Primates MAPK MAPK famplex_relations MAPK9 5601
Homo sapiens Primates MAPK MAPK famplex_relations MAPK10 5602
Homo sapiens Primates FAS FAS ncbigene_symbol FAS 355
Homo sapiens Primates FAS FAS ncbigene_synonym FASN 2194
Homo sapiens Primates EGFR EGFR ncbigene_symbol EGFR 1956
Homo sapiens Primates Notch NOTCH famplex_relations NOTCH1 4851
Homo sapiens Primates Notch NOTCH famplex_relations NOTCH2 4853
Homo sapiens Primates Notch NOTCH famplex_relations NOTCH3 4854
Homo sapiens Primates Notch NOTCH famplex_relations NOTCH4 4855
Homo sapiens Primates HAVCR1 HAVCR1 ncbigene_symbol HAVCR1 26762
Homo sapiens Primates PI3K/AKTSignaling PI3K ncbigene_synonym PIK3CA 5290
Homo sapiens Primates PI3K/AKTSignaling PI3K ncbigene_synonym PIK3CB 5291
Homo sapiens Primates PI3K/AKTSignaling PI3K ncbigene_synonym PIK3CD 5293
Homo sapiens Primates PI3K/AKTSignaling PI3K ncbigene_synonym PIK3CG 5294
Homo sapiens Primates PI3K/AKTSignaling PI3K famplex_relations PIK3R3 8503
Homo sapiens Primates PI3K/AKTSignaling PI3K famplex_relations PIK3R4 30849
Homo sapiens Primates PI3K/AKTSignaling PI3K famplex_relations PIK3R5 23533
Homo sapiens Primates PI3K/AKTSignaling PI3K famplex_relations PIK3R6 146850
Homo sapiens Primates PI3K/AKTSignaling PI3K famplex_relations PIK3R1 5295
Homo sapiens Primates PI3K/AKTSignaling PI3K famplex_relations PIK3R2 5296
Homo sapiens Primates AKT AKT ncbigene_synonym AKT1 207
Homo sapiens Primates AKT AKT famplex_relations AKT2 208
Homo sapiens Primates AKT AKT famplex_relations AKT3 10000
Homo sapiens Primates CASP CASP ncbigene_synonym CUX1 1523
Homo sapiens Primates CASP CASP ncbigene_synonym CYTIP 9595
Homo sapiens Primates CASP CASP ncbigene_synonym CRTAP 10491
Homo sapiens Primates VEGF VEGF ncbigene_synonym VEGFA 7422
Homo sapiens Primates VEGF VEGF famplex_relations VEGFB 7423
Homo sapiens Primates VEGF VEGF famplex_relations VEGFC 7424
Homo sapiens Primates VEGF VEGF famplex_relations VEGFD 2277
Homo sapiens Primates VEGF VEGF famplex_relations PGF 5228
Homo sapiens Primates SMAD3 SMAD3 ncbigene_symbol SMAD3 4088
Homo sapiens Primates p53 P53 ncbigene_synonym TP53 7157
Homo sapiens Primates p53 P53 famplex_relations TP63 8626
Homo sapiens Primates p53 P53 famplex_relations TP73 7161
Homo sapiens Primates FLI1 FLI1 ncbigene_symbol FLI1 2313
Homo sapiens Primates FLI1 FLI1 ncbigene_synonym FLII 2314
Homo sapiens Primates GM-CSF GMCSF ncbigene_synonym CSF2 1437
Homo sapiens Primates SP1 SP1 ncbigene_symbol SP1 6667
Homo sapiens Primates SP1 SP1 ncbigene_synonym PSG1 5669
Homo sapiens Primates SP1 SP1 ncbigene_synonym DAND5 199699
Homo sapiens Primates IGF-1 IGF1 ncbigene_symbol IGF1 3479
Homo sapiens Primates CDKN2A CDKN2A ncbigene_symbol CDKN2A 1029
Homo sapiens Primates TGF-B TGFB ncbigene_synonym TGFB1 7040
Homo sapiens Primates TGF-B TGFB famplex_relations TGFB2 7042
Homo sapiens Primates CCNE1 CCNE1 ncbigene_symbol CCNE1 898
Homo sapiens Primates ETV4 ETV4 ncbigene_symbol ETV4 2118
Homo sapiens Primates CNTF CNTF ncbigene_symbol CNTF 1270
Homo sapiens Primates Stat STAT ncbigene_synonym SOAT1 6646
Homo sapiens Primates Stat STAT famplex_relations STAT1 6772
Homo sapiens Primates Stat STAT famplex_relations STAT2 6773
Homo sapiens Primates Stat STAT famplex_relations STAT3 6774
Homo sapiens Primates Stat STAT famplex_relations STAT4 6775
Homo sapiens Primates Stat STAT famplex_relations STAT6 6778
Homo sapiens Primates Stat STAT famplex_relations STAT5A 6776
Homo sapiens Primates Stat STAT famplex_relations STAT5B 6777
Homo sapiens Primates JAK/StatSignaling JAK famplex_relations JAK1 3716
Homo sapiens Primates JAK/StatSignaling JAK famplex_relations JAK2 3717
Homo sapiens Primates JAK/StatSignaling JAK famplex_relations JAK3 3718
Homo sapiens Primates JAK/StatSignaling JAK famplex_relations TYK2 7297
Homo sapiens Primates EGF EGF ncbigene_symbol EGF 1950
Homo sapiens Primates BRCAI BRCAI ncbigene_synonym BRCA1 672
Homo sapiens Primates FGF FGF famplex_relations FGF1 2246
Homo sapiens Primates FGF FGF famplex_relations FGF2 2247
Homo sapiens Primates FGF FGF famplex_relations FGF3 2248
Homo sapiens Primates FGF FGF famplex_relations FGF4 2249
Homo sapiens Primates FGF FGF famplex_relations FGF5 2250
Homo sapiens Primates FGF FGF famplex_relations FGF6 2251
Homo sapiens Primates FGF FGF famplex_relations FGF7 2252
Homo sapiens Primates FGF FGF famplex_relations FGF8 2253
Homo sapiens Primates FGF FGF famplex_relations FGF9 2254
Homo sapiens Primates FGF FGF famplex_relations FGF10 2255
Homo sapiens Primates FGF FGF famplex_relations FGF11 2256
Homo sapiens Primates FGF FGF famplex_relations FGF12 2257
Homo sapiens Primates FGF FGF famplex_relations FGF13 2258
Homo sapiens Primates FGF FGF famplex_relations FGF14 2259
Homo sapiens Primates FGF FGF famplex_relations FGF16 8823
Homo sapiens Primates FGF FGF famplex_relations FGF17 8822
Homo sapiens Primates FGF FGF famplex_relations FGF18 8817
Homo sapiens Primates FGF FGF famplex_relations FGF19 9965
Homo sapiens Primates FGF FGF famplex_relations FGF20 26281
Homo sapiens Primates FGF FGF famplex_relations FGF21 26291
Homo sapiens Primates FGF FGF famplex_relations FGF22 27006
Homo sapiens Primates FGF FGF famplex_relations FGF23 8074
Homo sapiens Primates Hedgehog HEDGEHOG famplex_relations DHH 50846
Homo sapiens Primates Hedgehog HEDGEHOG famplex_relations IHH 3549
Homo sapiens Primates Hedgehog HEDGEHOG famplex_relations SHH 6469
Mus musculus Rodents ADAMTS ADAMTS ncbigene_synonym Adamts1 11504
Mus musculus Rodents B-catenin CTNNB1 ncbigene_symbol Ctnnb1 12387
Mus musculus Rodents TGFB3 TGFB3 ncbigene_symbol Tgfb3 21809
Mus musculus Rodents TÍMP1 TIMP1 ncbigene_symbol Timp1 21857
Mus musculus Rodents SPARC SPARC ncbigene_symbol Sparc 20692
Mus musculus Rodents PTEN PTEN ncbigene_symbol Pten 19211
Mus musculus Rodents ERK ERK ncbigene_synonym Ephb2 13844
Mus musculus Rodents ERK ERK ncbigene_synonym Mapk1 26413
Mus musculus Rodents FAS FAS ncbigene_symbol Fas 14102
Mus musculus Rodents FAS FAS ncbigene_synonym Fasn 14104
Mus musculus Rodents EGFR EGFR ncbigene_symbol Egfr 13649
Mus musculus Rodents HAVCR1 HAVCR1 ncbigene_symbol Havcr1 171283
Mus musculus Rodents PI3K/AKTSignaling PI3K ncbigene_synonym Pik3r1 18708
Mus musculus Rodents AKT AKT ncbigene_synonym Akt1 11651
Mus musculus Rodents CASP CASP ncbigene_synonym Crtap 56693
Mus musculus Rodents VEGF VEGF ncbigene_synonym Vegfa 22339
Mus musculus Rodents SMAD3 SMAD3 ncbigene_symbol Smad3 17127
Mus musculus Rodents p53 P53 ncbigene_synonym Trp53 22059
Mus musculus Rodents FLI1 FLI1 ncbigene_symbol Fli1 14247
Mus musculus Rodents GM-CSF GM-CSF ncbigene_synonym Csf2 12981
Mus musculus Rodents SP1 SP1 ncbigene_symbol Sp1 20683
Mus musculus Rodents IGF-1 IGF-1 ncbigene_synonym Igf1 16000
Mus musculus Rodents CDKN2A CDKN2A ncbigene_symbol Cdkn2a 12578
Mus musculus Rodents TGF-B TGFB ncbigene_synonym Tgfb1 21803
Mus musculus Rodents TGF-B TGFB ncbigene_synonym Ltbp1 268977
Mus musculus Rodents CCNE1 CCNE1 ncbigene_symbol Ccne1 12447
Mus musculus Rodents ETV4 ETV4 ncbigene_symbol Etv4 18612
Mus musculus Rodents CNTF CNTF ncbigene_symbol Cntf 12803
Mus musculus Rodents CNTF CNTF ncbigene_synonym Gm44505 664779
Mus musculus Rodents EGF EGF ncbigene_symbol Egf 13645
Mus musculus Rodents Fold FOLD ncbigene_synonym Ass1 11898
Danio rerio Vertebrates B-catenin CTNNB1 ncbigene_symbol ctnnb1 30265
Danio rerio Vertebrates TGFB3 TGFB3 ncbigene_symbol tgfb3 369195
Danio rerio Vertebrates SPARC SPARC ncbigene_symbol sparc 321357
Danio rerio Vertebrates PTEN PTEN ncbigene_synonym ptenb 368415
Danio rerio Vertebrates FAS FAS ncbigene_symbol fas 768248
Danio rerio Vertebrates EGFR EGFR ncbigene_synonym egfra 378478
Danio rerio Vertebrates HAVCR1 HAVCR1 ncbigene_symbol havcr1 436707
Danio rerio Vertebrates VEGF VEGF ncbigene_synonym vegfaa 30682
Danio rerio Vertebrates SMAD3 SMAD3 ncbigene_synonym smad3a 58092
Danio rerio Vertebrates p53 P53 ncbigene_synonym tp53 30590
Danio rerio Vertebrates FLI1 FLI1 ncbigene_symbol fli1 30619
Danio rerio Vertebrates SP1 SP1 ncbigene_symbol sp1 324109
Danio rerio Vertebrates IGF-1 IGF-1 ncbigene_synonym igf1 114433
Danio rerio Vertebrates CCNE1 CCNE1 ncbigene_symbol ccne1 30188
Danio rerio Vertebrates ETV4 ETV4 ncbigene_symbol etv4 30700
Danio rerio Vertebrates CNTF CNTF ncbigene_symbol cntf 100149185
Danio rerio Vertebrates Stat STAT ncbigene_synonym stat1b 368481
Danio rerio Vertebrates Stat STAT ncbigene_synonym stat4 368519
Danio rerio Vertebrates EGF EGF ncbigene_symbol egf 403045
Danio rerio Vertebrates EGF EGF ncbigene_synonym celsr1a 368436

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Cancer NA
Lung cancer NA