Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles

Cell Cycle pathway containing Treponema denticola differentially regulated genes in calvarial soft tissue compared with sham-infected controls at P ≤ 0.05, adapted from Pathway Express and using the Kyoto Encyclopedia of Genes and Genomes nomenclature. Red indicates induction, blue indicates repression, and green indicates no change in gene expression. An arrow indicates a molecular interaction resulting in mitogen-activated protein kinase (MAPK) signaling pathway, transforming growth factor-β (TGF-β) cytokine, apoptosis, ubiquitin-mediated proteolysis and a line without an arrowhead indicates a molecular interaction resulting in inhibition.
Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles
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Molecular characterization of Treponema denticola infection-induced bone and soft tissue transcriptional profiles. () V. Bakthavatchalu, et al. Mol Oral Microbiol. ;25(4):260-274. Figure: F5.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates Smel SMEI ncbigene_synonym SCN1A 6323
Homo sapiens Primates Slagl,25 S25 ncbigene_synonym RPS25 6230
Homo sapiens Primates DP-1,2 DP-1 ncbigene_synonym TFDP1 7027
Homo sapiens Primates SCP SCP ncbigene_synonym GAD1 2571
Homo sapiens Primates SCP SCP ncbigene_synonym SLC50A1 55974
Homo sapiens Primates SCP SCP ncbigene_synonym UCN3 114131
Homo sapiens Primates Espl ESP1 ncbigene_synonym TLE5 166
Homo sapiens Primates Espl ESP1 ncbigene_synonym CRIP2 1397
Homo sapiens Primates Espl ESP1 ncbigene_synonym ESPL1 9700
Homo sapiens Primates Espl ESP1 ncbigene_synonym PRSS21 10942
Homo sapiens Primates Mall MALL ncbigene_symbol MALL 7851
Homo sapiens Primates MAPK MAPK famplex_relations MAPK1 5594
Homo sapiens Primates MAPK MAPK famplex_relations MAPK3 5595
Homo sapiens Primates MAPK MAPK famplex_relations MAPK11 5600
Homo sapiens Primates MAPK MAPK famplex_relations MAPK12 6300
Homo sapiens Primates MAPK MAPK famplex_relations MAPK13 5603
Homo sapiens Primates MAPK MAPK famplex_relations MAPK14 1432
Homo sapiens Primates MAPK MAPK famplex_relations MAPK8 5599
Homo sapiens Primates MAPK MAPK famplex_relations MAPK9 5601
Homo sapiens Primates MAPK MAPK famplex_relations MAPK10 5602
Homo sapiens Primates APCC APCC famplex_relations ANAPC2 29882
Homo sapiens Primates APCC APCC famplex_relations ANAPC11 51529
Homo sapiens Primates APCC APCC famplex_relations ANAPC1 64682
Homo sapiens Primates APCC APCC famplex_relations CDC16 8881
Homo sapiens Primates APCC APCC famplex_relations CDC27 996
Homo sapiens Primates APCC APCC famplex_relations CDC23 8697
Homo sapiens Primates APCC APCC famplex_relations ANAPC5 51433
Homo sapiens Primates APCC APCC famplex_relations ANAPC10 10393
Homo sapiens Primates APCC APCC famplex_relations ANAPC15 25906
Homo sapiens Primates APCC APCC famplex_relations ANAPC13 25847
Homo sapiens Primates APCC APCC famplex_relations CDC26 246184
Homo sapiens Primates APCC APCC famplex_relations ANAPC16 119504
Homo sapiens Primates APCC APCC famplex_relations ANAPC7 51434
Homo sapiens Primates APCC APCC famplex_relations ANAPC4 29945
Homo sapiens Primates p16 P16 ncbigene_synonym CDKN2A 1029
Homo sapiens Primates p16 P16 ncbigene_synonym H3P10 115482713
Homo sapiens Primates pl8 P18 ncbigene_synonym CDKN2C 1031
Homo sapiens Primates pl8 P18 ncbigene_synonym UBE2I 7329
Homo sapiens Primates pl8 P18 ncbigene_synonym MAFK 7975
Homo sapiens Primates pl8 P18 ncbigene_synonym EEF1E1 9521
Homo sapiens Primates pl8 P18 ncbigene_synonym ZNF197 10168
Homo sapiens Primates pl8 P18 ncbigene_synonym ATRAID 51374
Homo sapiens Primates pl8 P18 ncbigene_synonym LAMTOR1 55004
Homo sapiens Primates pl8 P18 ncbigene_synonym TPPP2 122664
Homo sapiens Primates pl8 P18 ncbigene_synonym H3P12 100689229
Homo sapiens Primates pl8 PI8 ncbigene_synonym SERPINB8 5271
Homo sapiens Primates pl9 P19 ncbigene_synonym CDKN2D 1032
Homo sapiens Primates pl9 P19 ncbigene_synonym F9 2158
Homo sapiens Primates pl9 P19 ncbigene_synonym REG1A 5967
Homo sapiens Primates pl9 P19 ncbigene_synonym IL23A 51561
Homo sapiens Primates pl9 P19 ncbigene_synonym H3P13 115482685
Homo sapiens Primates pl9 PI9 ncbigene_synonym SERPINB9 5272
Homo sapiens Primates 1433e 1433E ncbigene_synonym YWHAE 7531
Homo sapiens Primates PCNA PCNA ncbigene_symbol PCNA 5111
Homo sapiens Primates CycH CYCH ncbigene_synonym CCNH 902
Homo sapiens Primates CDK7 CDK7 ncbigene_symbol CDK7 1022
Homo sapiens Primates Cyl CYI ncbigene_synonym CCNI 10983
Homo sapiens Primates CDK2 CDK2 ncbigene_symbol CDK2 1017
Homo sapiens Primates SCF SCF ncbigene_synonym KITLG 4254
Homo sapiens Primates Abl ABL ncbigene_synonym ABL1 25
Homo sapiens Primates Abl ABL ncbigene_synonym MTTP 4547
Homo sapiens Primates Abl ABL ncbigene_synonym DSP-AS1 101928076
Homo sapiens Primates Abl ABL famplex_relations ABL2 27
Homo sapiens Primates HDAC HDAC ncbigene_synonym HDAC9 9734
Homo sapiens Primates HDAC HDAC famplex_relations HDAC1 3065
Homo sapiens Primates HDAC HDAC famplex_relations HDAC2 3066
Homo sapiens Primates HDAC HDAC famplex_relations HDAC3 8841
Homo sapiens Primates HDAC HDAC famplex_relations HDAC8 55869
Homo sapiens Primates HDAC HDAC famplex_relations HDAC4 9759
Homo sapiens Primates HDAC HDAC famplex_relations HDAC5 10014
Homo sapiens Primates HDAC HDAC famplex_relations HDAC7 51564
Homo sapiens Primates HDAC HDAC famplex_relations HDAC6 10013
Homo sapiens Primates HDAC HDAC famplex_relations HDAC10 83933
Homo sapiens Primates HDAC HDAC famplex_relations SIRT1 23411
Homo sapiens Primates HDAC HDAC famplex_relations SIRT2 22933
Homo sapiens Primates HDAC HDAC famplex_relations SIRT3 23410
Homo sapiens Primates HDAC HDAC famplex_relations SIRT4 23409
Homo sapiens Primates HDAC HDAC famplex_relations SIRT5 23408
Homo sapiens Primates HDAC HDAC famplex_relations SIRT6 51548
Homo sapiens Primates HDAC HDAC famplex_relations SIRT7 51547
Homo sapiens Primates HDAC HDAC famplex_relations HDAC11 79885
Homo sapiens Primates MCM MCM ncbigene_synonym MMUT 4594
Homo sapiens Primates MCM MCM ncbigene_synonym PIK3CA 5290
Homo sapiens Primates MCM MCM famplex_relations MCM2 4171
Homo sapiens Primates MCM MCM famplex_relations MCM3 4172
Homo sapiens Primates MCM MCM famplex_relations MCM4 4173
Homo sapiens Primates MCM MCM famplex_relations MCM5 4174
Homo sapiens Primates MCM MCM famplex_relations MCM6 4175
Homo sapiens Primates MCM MCM famplex_relations MCM7 4176
Homo sapiens Primates MCM MCM famplex_relations MCM8 84515
Homo sapiens Primates MCM MCM famplex_relations MCM9 254394
Homo sapiens Primates MCM MCM famplex_relations MCMDC2 157777
Homo sapiens Primates E2F1,2,3 E2F1 ncbigene_symbol E2F1 1869
Homo sapiens Primates E2F1,2,3 E2F1 ncbigene_synonym UBE2L3 7332
Homo sapiens Primates Mema MEMA ncbigene_synonym PNN 5411
Homo sapiens Primates Orc2 ORC2 ncbigene_symbol ORC2 4999
Homo sapiens Primates Orc2 ORC2 ncbigene_synonym SLC25A2 83884
Homo sapiens Primates GI GI famplex_relations GNAO1 2775
Homo sapiens Primates GI GI famplex_relations GNAI1 2770
Homo sapiens Primates GI GI famplex_relations GNAI2 2771
Homo sapiens Primates GI GI famplex_relations GNAI3 2773
Homo sapiens Primates GI GI famplex_relations GNAT1 2779
Homo sapiens Primates GI GI famplex_relations GNAT2 2780
Homo sapiens Primates GI GI famplex_relations GNAT3 346562
Homo sapiens Primates GI GI famplex_relations GNAZ 2781
Homo sapiens Primates G2 G2 ncbigene_synonym WARS1 7453
Drosophila melanogaster Invertebrates CYCLE CYCLE ncbigene_synonym CycE 34924
Drosophila melanogaster Invertebrates CYCLE CYCLE ncbigene_synonym cyc 40162
Drosophila melanogaster Invertebrates Slagl,25 S25 ncbigene_synonym RpS25 41343
Drosophila melanogaster Invertebrates DP-1,2 DP1 ncbigene_symbol Dp1 37116
Drosophila melanogaster Invertebrates DP-1,2 DP1 ncbigene_synonym Dp 36461
Drosophila melanogaster Invertebrates DP-1,2 DP1 ncbigene_synonym Aplip1 53472
Drosophila melanogaster Invertebrates SCP SCP ncbigene_symbol scp 44860
Drosophila melanogaster Invertebrates SCP SCP ncbigene_synonym Scp1 3355102
Drosophila melanogaster Invertebrates Espl ESPL ncbigene_synonym E(spl)m7-HLH 43160
Drosophila melanogaster Invertebrates Espl ESPL ncbigene_synonym E(spl)m8-HLH 43161
Drosophila melanogaster Invertebrates Skpa SKPA ncbigene_symbol SkpA 31016
Drosophila melanogaster Invertebrates Mall MALI ncbigene_symbol mali 5658063
Drosophila melanogaster Invertebrates MAPK MAPK ncbigene_synonym MKP-4 32963
Drosophila melanogaster Invertebrates MAPK MAPK ncbigene_synonym p38b 34780
Drosophila melanogaster Invertebrates MAPK MAPK ncbigene_synonym rl 3354888
Drosophila melanogaster Invertebrates tu TU ncbigene_symbol Tu 44537
Drosophila melanogaster Invertebrates p16 P16 ncbigene_synonym Zdhhc8 31887
Drosophila melanogaster Invertebrates p16 P16 ncbigene_synonym Arpc5 33444
Drosophila melanogaster Invertebrates p16 P16 ncbigene_synonym Su(osk)P16 250692
Drosophila melanogaster Invertebrates pl8 P18 ncbigene_synonym cac 32158
Drosophila melanogaster Invertebrates pl8 P18 ncbigene_synonym Lamtor1 40193
Drosophila melanogaster Invertebrates pl8 P18 ncbigene_synonym MED21 3354977
Drosophila melanogaster Invertebrates pl9 P19 ncbigene_synonym caz 32587
Drosophila melanogaster Invertebrates pl9 P19 ncbigene_synonym l(1)20Ca 48279
Drosophila melanogaster Invertebrates 1433e 1433E ncbigene_symbol 14-3-3epsilon 42186
Drosophila melanogaster Invertebrates PCNA PCNA ncbigene_symbol PCNA 37290
Drosophila melanogaster Invertebrates CHE CHE ncbigene_symbol che 248109
Drosophila melanogaster Invertebrates CHE CHE ncbigene_synonym Ace 41625
Drosophila melanogaster Invertebrates CycH CYCH ncbigene_symbol CycH 40429
Drosophila melanogaster Invertebrates CDK7 CDK7 ncbigene_symbol Cdk7 31441
Drosophila melanogaster Invertebrates Cyl CY1 ncbigene_synonym Cyt-c1 38612
Drosophila melanogaster Invertebrates Cyl CY1 ncbigene_synonym Cyt-c1L 43457
Drosophila melanogaster Invertebrates CDK2 CDK2 ncbigene_symbol Cdk2 42453
Drosophila melanogaster Invertebrates START) START ncbigene_synonym Start1 37927
Drosophila melanogaster Invertebrates PRI PRI ncbigene_symbol Pri 47191
Drosophila melanogaster Invertebrates PRI PRI ncbigene_synonym Arr2 38993
Drosophila melanogaster Invertebrates PRI PRI ncbigene_synonym tal-2A 7354376
Drosophila melanogaster Invertebrates PRI PRI ncbigene_synonym tal-AA 7354377
Drosophila melanogaster Invertebrates PRI PRI ncbigene_synonym tal-3A 7354378
Drosophila melanogaster Invertebrates PRI PRI ncbigene_synonym tal-1A 7354381
Drosophila melanogaster Invertebrates SCF SCF ncbigene_symbol scf 38145
Drosophila melanogaster Invertebrates Abl ABL ncbigene_symbol Abl 45821
Drosophila melanogaster Invertebrates Abl ABI ncbigene_symbol Abi 41718
Drosophila melanogaster Invertebrates Myt! MYT ncbigene_synonym Myt1 38649
Drosophila melanogaster Invertebrates Wee WEE ncbigene_synonym Wee1 33965
Drosophila melanogaster Invertebrates HDAC HDAC ncbigene_synonym HDAC4 32278
Drosophila melanogaster Invertebrates HDAC HDAC ncbigene_synonym HDAC6 32461
Drosophila melanogaster Invertebrates HDAC HDAC ncbigene_synonym HDAC1 38565
Drosophila melanogaster Invertebrates HDAC HDAC ncbigene_synonym HDAC3 44446
Drosophila melanogaster Invertebrates ORC ORC ncbigene_synonym Orc5 34794
Drosophila melanogaster Invertebrates ORC ORC ncbigene_synonym Orc1 35686
Drosophila melanogaster Invertebrates ORC ORC ncbigene_synonym Orc6 36017
Drosophila melanogaster Invertebrates ORC ORC ncbigene_synonym Orc3 36454
Drosophila melanogaster Invertebrates ORC ORC ncbigene_synonym Orc4 37970
Drosophila melanogaster Invertebrates ORC ORC ncbigene_synonym Orc2 41703
Drosophila melanogaster Invertebrates E2F43E2F1,2,3 E3 ncbigene_symbol E3 5658048
Drosophila melanogaster Invertebrates E2F1,2,3 E2F1 ncbigene_symbol E2f1 42550
Drosophila melanogaster Invertebrates (Mira MIRA ncbigene_symbol mira 42379
Drosophila melanogaster Invertebrates Mem MEM ncbigene_synonym Men 47173
Drosophila melanogaster Invertebrates Mu MU ncbigene_symbol mu 249940
Drosophila melanogaster Invertebrates Ore4 ORE4 ncbigene_synonym CG7329 34457
Drosophila melanogaster Invertebrates Orcó ORCO ncbigene_symbol Orco 40650
Drosophila melanogaster Invertebrates Orcó ORCO ncbigene_synonym Orcokinin 37806
Drosophila melanogaster Invertebrates G2 G2 ncbigene_synonym anon-70Dc 5657482

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID