Toll-like recepter 4 signaling pathway modified from Wikipedia Commons

Diagram of the Toll-like recepter 4 signaling pathway modified from Wikipedia Commons.
Toll-like recepter 4 signaling pathway modified from Wikipedia Commons
Download JPG
View figure at PMC Read paper at PMC Open at NDEx
PMC
NDEx

Publication

Mallory-Denk body pathogenesis revisited. (2010) Samuel W French, et al. World J Hepatol. 2010 Aug 27;2(8):295-301. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates LPS LPS ncbigene_synonym IRF6 3664
Homo sapiens Primates LBP LBP ncbigene_symbol LBP 3929
Homo sapiens Primates LBP LBP ncbigene_synonym EHHADH 1962
Homo sapiens Primates LBP LBP ncbigene_synonym RPSA 3921
Homo sapiens Primates MD2 MD2 ncbigene_synonym LY96 23643
Homo sapiens Primates TLR4 TLR4 ncbigene_symbol TLR4 7099
Homo sapiens Primates CD14 CD14 ncbigene_symbol CD14 929
Homo sapiens Primates CD14 CD14 ncbigene_synonym NDUFA2 4695
Homo sapiens Primates Traf6 TRAF6 ncbigene_symbol TRAF6 7189
Homo sapiens Primates Irak1 IRAK1 ncbigene_symbol IRAK1 3654
Homo sapiens Primates Tak1 TAK1 ncbigene_synonym MAP3K7 6885
Homo sapiens Primates Tak1 TAK1 ncbigene_synonym NR2C2 7182
Homo sapiens Primates Trif TRIF ncbigene_synonym TRIM69 140691
Homo sapiens Primates Trif TRIF ncbigene_synonym TICAM1 148022
Homo sapiens Primates Tbk1 TBK1 ncbigene_symbol TBK1 29110
Homo sapiens Primates Rip RIP ncbigene_synonym AGFG1 3267
Homo sapiens Primates Rip RIP ncbigene_synonym RIPK1 8737
Homo sapiens Primates Rip RIP ncbigene_synonym DCAF1 9730
Homo sapiens Primates Rip RIP ncbigene_synonym RPAIN 84268
Homo sapiens Primates Irak4 IRAK4 ncbigene_symbol IRAK4 51135
Homo sapiens Primates (IKKI IKKI ncbigene_synonym IKBKE 9641
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CA 5290
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CB 5291
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CD 5293
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CG 5294
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R3 8503
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R4 30849
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R5 23533
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R6 146850
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R1 5295
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R2 5296
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K1 4214
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K2 10746
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K3 4215
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K4 4216
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K5 4217
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K6 9064
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K8 1326
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K9 4293
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K10 4294
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K11 4296
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K12 7786
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K13 9175
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K14 9020
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K15 389840
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K19 80122
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K20 51776
Homo sapiens Primates Map3Ks MAP3K famplex_relations MAP3K21 84451
Homo sapiens Primates Map3Ks MAP3K famplex_relations ARAF 369
Homo sapiens Primates Map3Ks MAP3K famplex_relations BRAF 673
Homo sapiens Primates Map3Ks MAP3K famplex_relations RAF1 5894
Homo sapiens Primates Map3Ks MAP3K famplex_relations TAOK1 57551
Homo sapiens Primates Map3Ks MAP3K famplex_relations TAOK2 9344
Homo sapiens Primates Map3Ks MAP3K famplex_relations TAOK3 51347
Homo sapiens Primates MKK3/6 MKK3 ncbigene_synonym MAP2K3 5606
Homo sapiens Primates MKK3/6 MKK6 ncbigene_synonym MAP2K6 5608
Homo sapiens Primates Mek1 MEK1 ncbigene_synonym MAP2K1 5604
Homo sapiens Primates Mkk4 MKK4 ncbigene_synonym MAP2K4 6416
Homo sapiens Primates IKBA IKBA ncbigene_synonym NFKBIA 4792
Homo sapiens Primates (Akt AKT ncbigene_synonym AKT1 207
Homo sapiens Primates (Akt AKT famplex_relations AKT2 208
Homo sapiens Primates (Akt AKT famplex_relations AKT3 10000
Homo sapiens Primates ERK1 ERK1 ncbigene_synonym MAPK3 5595
Homo sapiens Primates ERK1/2 ERK2 ncbigene_synonym MAPK1 5594
Homo sapiens Primates JNK JNK ncbigene_synonym MAPK8 5599
Homo sapiens Primates JNK JNK famplex_relations MAPK9 5601
Homo sapiens Primates JNK JNK famplex_relations MAPK10 5602
Homo sapiens Primates p38 P38 ncbigene_synonym CRK 1398
Homo sapiens Primates p38 P38 ncbigene_synonym MAPK14 1432
Homo sapiens Primates p38 P38 ncbigene_synonym AIMP2 7965
Homo sapiens Primates p38 P38 ncbigene_synonym GRAP2 9402
Homo sapiens Primates p38 P38 ncbigene_synonym AHSA1 10598
Homo sapiens Primates p38 P38 ncbigene_synonym POLDIP2 26073
Homo sapiens Primates p38 P38 famplex_relations MAPK11 5600
Homo sapiens Primates p38 P38 famplex_relations MAPK12 6300
Homo sapiens Primates p38 P38 famplex_relations MAPK13 5603
Homo sapiens Primates (AP-1 AP1 ncbigene_synonym FOS 2353
Homo sapiens Primates (AP-1 AP1 ncbigene_synonym FOSB 2354
Homo sapiens Primates (AP-1 AP1 ncbigene_synonym JUN 3725
Homo sapiens Primates (AP-1 AP1 ncbigene_synonym JUNB 3726
Homo sapiens Primates (AP-1 AP1 ncbigene_synonym JUND 3727
Homo sapiens Primates (AP-1 AP1 famplex_relations FOSL1 8061
Homo sapiens Primates (AP-1 AP1 famplex_relations FOSL2 2355
Homo sapiens Primates NFKB NFKB ncbigene_synonym NFKB1 4790
Homo sapiens Primates NFKB NFKB famplex_relations RELA 5970
Homo sapiens Primates NFKB NFKB famplex_relations RELB 5971
Homo sapiens Primates NFKB NFKB famplex_relations REL 5966
Homo sapiens Primates NFKB NFKB famplex_relations NFKB2 4791
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNK 56832
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNW1 3467
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA1 3439
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA2 3440
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA4 3441
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA5 3442
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA6 3443
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA7 3444
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA8 3445
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA10 3446
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA13 3447
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA14 3448
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA16 3449
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA17 3451
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNA21 3452
Homo sapiens Primates Interferon INTERFERON famplex_relations IFNB1 3456
Homo sapiens Primates MYD88 MYD88 ncbigene_symbol MYD88 4615
Homo sapiens Primates Tirap TIRAP ncbigene_symbol TIRAP 114609
Homo sapiens Primates Tram TRAM ncbigene_synonym TRAM1 23471
Homo sapiens Primates Tram TRAM ncbigene_synonym TICAM2 353376
Homo sapiens Primates Tram TRAM ncbigene_synonym TMED7-TICAM2 100302736

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Cancer NA