FC-66 expression of the Ingenuity NFKB Signaling canonical pathway

FC-66 expression of the Ingenuity NF-κB Signaling canonical pathway. Ingenuity software overlaid gene expression loadings from FC-66 onto a pre-designed pathway. Red = over-expressed in PTL-treated versus untreated, green = under-expressed.
FC-66 expression of the Ingenuity NFKB Signaling canonical pathway
Download JPG
View figure at PMC Read paper at PMC Open at NDEx
PMC
NDEx

Publication

Independent component analysis: mining microarray data for fundamental human gene expression modules. () Jesse M. Engreitz, et al. J Biomed Inform. ;43(6):932-944. Figure: F5.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Danio rerio Vertebrates BMP2/4 BMP2 ncbigene_synonym bmp2a 30631
Danio rerio Vertebrates BMP2/4 BMP2 ncbigene_synonym bmp2b 30632
Danio rerio Vertebrates BMP2/4 BMP4 ncbigene_symbol bmp4 30612
Danio rerio Vertebrates EGF EGF ncbigene_symbol egf 403045
Danio rerio Vertebrates EGF EGF ncbigene_synonym celsr1a 368436
Danio rerio Vertebrates NGF NGF ncbigene_synonym ngfb 58133
Danio rerio Vertebrates TGF-a TGFA ncbigene_symbol tgfa 100034402
Danio rerio Vertebrates LTA LTA ncbigene_symbol lta 554305
Danio rerio Vertebrates receptor RECEPTOR ncbigene_synonym kita 30256
Danio rerio Vertebrates receptor RECEPTOR ncbigene_synonym ngfra 100535003
Danio rerio Vertebrates TRAP TRAP ncbigene_synonym acp5a 406801
Danio rerio Vertebrates TIRAP TIRAP ncbigene_symbol tirap 403148
Danio rerio Vertebrates TRAF6 TRAF6 ncbigene_symbol traf6 554561
Danio rerio Vertebrates LCK LCK ncbigene_symbol lck 414333
Danio rerio Vertebrates Ras RAS ncbigene_synonym rab1ab 368883
Danio rerio Vertebrates Zap70 ZAP70 ncbigene_symbol zap70 553615
Danio rerio Vertebrates ÚBE2N UBE2N ncbigene_synonym ube2na 406807
Danio rerio Vertebrates UBE2V1 UBE2V1 ncbigene_symbol ube2v1 641324
Danio rerio Vertebrates PLCY2 PLCG2 ncbigene_symbol plcg2 561747
Danio rerio Vertebrates PKR PKR ncbigene_synonym eif2ak2 100001092
Danio rerio Vertebrates NF-KB1 NFKB1 ncbigene_symbol nfkb1 565756
Danio rerio Vertebrates NF-KB2 NFKB2 ncbigene_symbol nfkb2 415100
Danio rerio Vertebrates RelA RELA ncbigene_symbol rela 415099
Danio rerio Vertebrates RelB RELB ncbigene_symbol relb 795414
Danio rerio Vertebrates HDAC1)2 HDAC12 ncbigene_symbol hdac12 100148903
Homo sapiens Primates NFKB NFKB ncbigene_synonym NFKB1 4790
Homo sapiens Primates NFKB NFKB famplex_relations RELA 5970
Homo sapiens Primates NFKB NFKB famplex_relations RELB 5971
Homo sapiens Primates NFKB NFKB famplex_relations REL 5966
Homo sapiens Primates NFKB NFKB famplex_relations NFKB2 4791
Homo sapiens Primates BMP2/4 BMP2 ncbigene_symbol BMP2 650
Homo sapiens Primates BMP2/4 BMP4 ncbigene_symbol BMP4 652
Homo sapiens Primates RANKL RANKL ncbigene_synonym TNFSF11 8600
Homo sapiens Primates EGF EGF ncbigene_symbol EGF 1950
Homo sapiens Primates IL-1 IL-1 ncbigene_synonym IL1B 3553
Homo sapiens Primates NGF NGF ncbigene_symbol NGF 4803
Homo sapiens Primates TGF-a TGFA ncbigene_symbol TGFA 7039
Homo sapiens Primates CD40L CD40L ncbigene_synonym CD40LG 959
Homo sapiens Primates LTA LTA ncbigene_symbol LTA 4049
Homo sapiens Primates BAFF BAFF ncbigene_synonym TNFSF13B 10673
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR1 7096
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR2 7097
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR3 7098
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR4 7099
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR5 7100
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR6 10333
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR7 51284
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR8 51311
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR9 54106
Homo sapiens Primates I1-IR/TLR TLR famplex_relations TLR10 81793
Homo sapiens Primates TNFR TNFR ncbigene_synonym TNFRSF1A 7132
Homo sapiens Primates D4 D4 ncbigene_synonym DLL4 54567
Homo sapiens Primates TRAP TRAP ncbigene_symbol TRAP 100187907
Homo sapiens Primates TRAP TRAP ncbigene_synonym ACP5 54
Homo sapiens Primates TRAP TRAP ncbigene_synonym TRAF2 7186
Homo sapiens Primates TRAP TRAP ncbigene_synonym TRRAP 8295
Homo sapiens Primates TRAP TRAP ncbigene_synonym TDRD7 23424
Homo sapiens Primates TRAP TRAP ncbigene_synonym SCYL1 57410
Homo sapiens Primates TIRAP TIRAP ncbigene_symbol TIRAP 114609
Homo sapiens Primates TRAF TRAF famplex_relations TRAF1 7185
Homo sapiens Primates TRAF TRAF famplex_relations TRAF3 7187
Homo sapiens Primates TRAF TRAF famplex_relations TRAF4 9618
Homo sapiens Primates TRAF TRAF famplex_relations TRAF5 7188
Homo sapiens Primates TRAF TRAF famplex_relations TRAF6 7189
Homo sapiens Primates TRAF TRAF famplex_relations TRAF7 84231
Homo sapiens Primates LCK LCK ncbigene_symbol LCK 3932
Homo sapiens Primates Ras RAS famplex_relations KRAS 3845
Homo sapiens Primates Ras RAS famplex_relations HRAS 3265
Homo sapiens Primates Ras RAS famplex_relations NRAS 4893
Homo sapiens Primates RIP RIP ncbigene_synonym AGFG1 3267
Homo sapiens Primates RIP RIP ncbigene_synonym RIPK1 8737
Homo sapiens Primates RIP RIP ncbigene_synonym DCAF1 9730
Homo sapiens Primates RIP RIP ncbigene_synonym RPAIN 84268
Homo sapiens Primates Zap70 ZAP70 ncbigene_symbol ZAP70 7535
Homo sapiens Primates RAK1 RAK1 ncbigene_synonym RNASE9 390443
Homo sapiens Primates A20 A20 ncbigene_synonym TNFAIP3 7128
Homo sapiens Primates A20 A20 ncbigene_synonym IGKV1-27 28935
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CA 5290
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CB 5291
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CD 5293
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CG 5294
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R3 8503
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R4 30849
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R5 23533
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R6 146850
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R1 5295
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R2 5296
Homo sapiens Primates ÚBE2N UBE2N ncbigene_symbol UBE2N 7334
Homo sapiens Primates UBE2V1 UBE2V1 ncbigene_symbol UBE2V1 7335
Homo sapiens Primates PLCY2 PLCG2 ncbigene_symbol PLCG2 5336
Homo sapiens Primates NIK NIK ncbigene_synonym MAP3K14 9020
Homo sapiens Primates NIK NIK ncbigene_synonym MAP4K4 9448
Homo sapiens Primates PKR PKR ncbigene_synonym EIF2AK2 5610
Homo sapiens Primates MEKK3 MEKK3 ncbigene_synonym MAP3K3 4215
Homo sapiens Primates AKT AKT ncbigene_synonym AKT1 207
Homo sapiens Primates AKT AKT famplex_relations AKT2 208
Homo sapiens Primates AKT AKT famplex_relations AKT3 10000
Homo sapiens Primates PKC PKC ncbigene_synonym PRRT2 112476
Homo sapiens Primates PKC PKC famplex_relations PRKCA 5578
Homo sapiens Primates PKC PKC famplex_relations PRKCB 5579
Homo sapiens Primates PKC PKC famplex_relations PRKCD 5580
Homo sapiens Primates PKC PKC famplex_relations PRKCE 5581
Homo sapiens Primates PKC PKC famplex_relations PRKCG 5582
Homo sapiens Primates PKC PKC famplex_relations PRKCH 5583
Homo sapiens Primates PKC PKC famplex_relations PRKCI 5584
Homo sapiens Primates PKC PKC famplex_relations PRKCQ 5588
Homo sapiens Primates PKC PKC famplex_relations PRKCZ 5590
Homo sapiens Primates PKC PKC famplex_relations PRKD3 23683
Homo sapiens Primates Cot COT ncbigene_synonym MAP3K8 1326
Homo sapiens Primates Cot COT ncbigene_synonym CROT 54677
Homo sapiens Primates IKKE IKKE ncbigene_synonym IKBKE 9641
Homo sapiens Primates B-TrCP B-TRCP ncbigene_synonym BTRC 8945
Homo sapiens Primates NK1 NK1 ncbigene_synonym CD160 11126
Homo sapiens Primates NK1 NK1 ncbigene_synonym B3GAT1 27087
Homo sapiens Primates MKK6/7NK1 MKK6 ncbigene_synonym MAP2K6 5608
Homo sapiens Primates IKKA IKKA ncbigene_synonym CHUK 1147
Homo sapiens Primates p52 P52 ncbigene_synonym FKBP4 2288
Homo sapiens Primates p52 P52 ncbigene_synonym GTF2H4 2968
Homo sapiens Primates p52 P52 ncbigene_synonym PMPCB 9512
Homo sapiens Primates p52 P52 ncbigene_synonym PSIP1 11168
Homo sapiens Primates p52 P52 ncbigene_synonym H3P42 115482704
Homo sapiens Primates p65 P65 ncbigene_synonym SYT1 6857
Homo sapiens Primates p65 P65 ncbigene_synonym GORASP1 64689
Homo sapiens Primates p65 P65 ncbigene_synonym WNK1 65125
Homo sapiens Primates p100 P100 ncbigene_synonym CUX1 1523
Homo sapiens Primates p100 P100 ncbigene_synonym OAS3 4940
Homo sapiens Primates p100 P100 ncbigene_synonym PMEL 6490
Homo sapiens Primates p100 P100 ncbigene_synonym SART3 9733
Homo sapiens Primates p100 P100 ncbigene_synonym TPX2 22974
Homo sapiens Primates p100 P100 ncbigene_synonym SND1 27044
Homo sapiens Primates p100 P100 ncbigene_synonym ASCC2 84164
Homo sapiens Primates CK2 CK2 famplex_relations CSNK2A1 1457
Homo sapiens Primates CK2 CK2 famplex_relations CSNK2A2 1459
Homo sapiens Primates CK2 CK2 famplex_relations CSNK2B 1460
Homo sapiens Primates CBP/p300 CBP ncbigene_synonym CREBBP 1387
Homo sapiens Primates CBP/p300 CBP ncbigene_synonym EIF4E 1977
Homo sapiens Primates CBP/p300 CBP ncbigene_synonym OPN1LW 5956
Homo sapiens Primates CBP/p300 CBP ncbigene_synonym PAG1 55824
Homo sapiens Primates CBP/p300 CBP ncbigene_synonym PCBP4 57060
Homo sapiens Primates CBP/p300 P300 ncbigene_synonym EP300 2033
Homo sapiens Primates p50 P50 ncbigene_synonym CD40 958
Homo sapiens Primates p50 P50 ncbigene_synonym ARHGEF7 8874
Homo sapiens Primates p50 P50 ncbigene_synonym ASCC1 51008
Homo sapiens Primates p50 P50 ncbigene_synonym H3P40 115482723

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Cancer NA
Rheumatoid arthritis NA