PIK3/Akt/mTOR Pathway
PIK3/Akt/mTOR Pathway.
Publication
Targeted Therapy for Advanced Prostate Cancer: Inhibition of the PI3K/Akt/mTOR Pathway. () Todd M. Morgan, et al. Curr Cancer Drug Targets. ;9(2):237-249. Figure: F1.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Drosophila melanogaster | Invertebrates | PI3K | PI3K | ncbigene_synonym | Pi3K21B | 33203 |
| Drosophila melanogaster | Invertebrates | PI3K | PI3K | ncbigene_synonym | Pi3K59F | 37733 |
| Drosophila melanogaster | Invertebrates | PI3K | PI3K | ncbigene_synonym | Pi3K68D | 39329 |
| Drosophila melanogaster | Invertebrates | PI3K | PI3K | ncbigene_synonym | Pi3K92E | 42446 |
| Drosophila melanogaster | Invertebrates | AKT | AKT | ncbigene_symbol | Akt | 41957 |
| Drosophila melanogaster | Invertebrates | MTOR | MTOR | ncbigene_symbol | Mtor | 36264 |
| Drosophila melanogaster | Invertebrates | MTOR | MTOR | ncbigene_synonym | Tor | 47396 |
| Drosophila melanogaster | Invertebrates | PDK1 | PDK1 | ncbigene_symbol | Pdk1 | 38017 |
| Drosophila melanogaster | Invertebrates | PTEN | PTEN | ncbigene_symbol | Pten | 43991 |
| Drosophila melanogaster | Invertebrates | P70-S6K | P70S6K | ncbigene_synonym | S6k | 38654 |
| Drosophila melanogaster | Invertebrates | 4E-BP1 | 4E-BP1 | ncbigene_synonym | Thor | 33569 |
| Drosophila melanogaster | Invertebrates | elF4E | ELF4E | ncbigene_synonym | eIF4E1 | 45525 |
| Drosophila melanogaster | Invertebrates | elF4E | EIF4E | ncbigene_synonym | eIF4E7 | 31059 |
| Drosophila melanogaster | Invertebrates | elF4E | EIF4E | ncbigene_synonym | eIF4E4 | 38743 |
| Drosophila melanogaster | Invertebrates | elF4E | EIF4E | ncbigene_synonym | eIF4E5 | 38878 |
| Drosophila melanogaster | Invertebrates | elF4E | EIF4E | ncbigene_synonym | eIF4E3 | 38923 |
| Drosophila melanogaster | Invertebrates | elF4E | EIF4E | ncbigene_synonym | eIF4E6 | 43422 |
| Drosophila melanogaster | Invertebrates | elF4E | EIF4E | ncbigene_synonym | eIF4EHP | 326255 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CA | 5290 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CB | 5291 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CD | 5293 |
| Homo sapiens | Primates | PI3K | PI3K | ncbigene_synonym | PIK3CG | 5294 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R3 | 8503 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R4 | 30849 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R5 | 23533 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R6 | 146850 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R1 | 5295 |
| Homo sapiens | Primates | PI3K | PI3K | famplex_relations | PIK3R2 | 5296 |
| Homo sapiens | Primates | AKT | AKT | ncbigene_synonym | AKT1 | 207 |
| Homo sapiens | Primates | AKT | AKT | famplex_relations | AKT2 | 208 |
| Homo sapiens | Primates | AKT | AKT | famplex_relations | AKT3 | 10000 |
| Homo sapiens | Primates | MTOR | MTOR | ncbigene_symbol | MTOR | 2475 |
| Homo sapiens | Primates | PDK1 | PDK1 | ncbigene_symbol | PDK1 | 5163 |
| Homo sapiens | Primates | PDK1 | PDK1 | ncbigene_synonym | PDPK1 | 5170 |
| Homo sapiens | Primates | PTEN | PTEN | ncbigene_symbol | PTEN | 5728 |
| Homo sapiens | Primates | P70-S6K | P70-S6K | ncbigene_synonym | RPS6KB1 | 6198 |
| Homo sapiens | Primates | 4E-BP1 | 4E-BP1 | ncbigene_synonym | EIF4EBP1 | 1978 |
| Homo sapiens | Primates | elF4E | EIF4E | ncbigene_symbol | EIF4E | 1977 |
| Homo sapiens | Primates | elF4E | EIF4E | famplex_relations | EIF4E2 | 9470 |
| Homo sapiens | Primates | elF4E | EIF4E | famplex_relations | EIF4E3 | 317649 |
| Word | Match | MeSH | Name | ChEBI |
|---|
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|