Proposed role for AMPK in the kidney in coupling catabolic pathways requiring ATP hydrolysis (primarily sodium transport) with metabolic pathways leading to ATP synthesis (primarily fatty acid and glucose oxidation)
Proposed role for AMPK in the kidney in coupling catabolic pathways requiring ATP hydrolysis (primarily sodium transport) with metabolic pathways leading to ATP synthesis (primarily fatty acid and glucose oxidation). +, Activating pathway; −, inhibitory pathway.

Publication
Role of the energy sensor AMP-activated protein kinase in renal physiology and disease. (2010) Kenneth R. Hallows, et al. Am J Physiol Renal Physiol. 2010 May;298(5):F1067-F1077. Figure: F2.Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
---|---|---|---|---|---|---|
Drosophila melanogaster | Invertebrates | Na | NA | ncbigene_symbol | na | 45338 |
Drosophila melanogaster | Invertebrates | ATP | ATP | ncbigene_synonym | ATPsynbeta | 43829 |
Drosophila melanogaster | Invertebrates | ATP | ATP | ncbigene_synonym | Atpalpha | 48971 |
Drosophila melanogaster | Invertebrates | AMPK | AMPK | ncbigene_synonym | SNF4Agamma | 42515 |
Drosophila melanogaster | Invertebrates | AMPK | AMPK | ncbigene_synonym | AMPKalpha | 43904 |
Drosophila melanogaster | Invertebrates | ACC | ACC | ncbigene_symbol | ACC | 35761 |
Drosophila melanogaster | Invertebrates | ACC | ACC | ncbigene_synonym | tacc | 40589 |
Drosophila melanogaster | Invertebrates | ACC | ACC | ncbigene_synonym | acclinal-wing | 247733 |
Drosophila melanogaster | Invertebrates | CFTR | CFTR | ncbigene_symbol | Cftr | 42928 |
Drosophila melanogaster | Invertebrates | NKCC | NKCC | ncbigene_symbol | NKCC | 40663 |
Drosophila melanogaster | Invertebrates | NKCC | NKCC | ncbigene_synonym | Ncc69 | 39410 |
Drosophila melanogaster | Invertebrates | EEF2 | EEF2 | ncbigene_symbol | eEF2 | 35422 |
Drosophila melanogaster | Invertebrates | EEF2 | EEF2 | ncbigene_synonym | CG4849 | 43358 |
Drosophila melanogaster | Invertebrates | MTOR, | MTOR | ncbigene_symbol | Mtor | 36264 |
Drosophila melanogaster | Invertebrates | MTOR, | MTOR | ncbigene_synonym | Tor | 47396 |
Homo sapiens | Primates | ATP | ATP | ncbigene_synonym | ATP8A2 | 51761 |
Homo sapiens | Primates | AMPK | AMPK | ncbigene_synonym | PRKAA1 | 5562 |
Homo sapiens | Primates | AMPK | AMPK | ncbigene_synonym | PRKAA2 | 5563 |
Homo sapiens | Primates | AMPK | AMPK | ncbigene_synonym | PRKAB1 | 5564 |
Homo sapiens | Primates | AMPK | AMPK | famplex_relations | PRKAB2 | 5565 |
Homo sapiens | Primates | AMPK | AMPK | famplex_relations | PRKAG1 | 5571 |
Homo sapiens | Primates | AMPK | AMPK | famplex_relations | PRKAG2 | 51422 |
Homo sapiens | Primates | AMPK | AMPK | famplex_relations | PRKAG3 | 53632 |
Homo sapiens | Primates | ACC | ACC | ncbigene_synonym | ACACA | 31 |
Homo sapiens | Primates | ACC | ACC | ncbigene_synonym | BMS1 | 9790 |
Homo sapiens | Primates | ACC | ACC | famplex_relations | ACACB | 32 |
Homo sapiens | Primates | CFTR | CFTR | ncbigene_symbol | CFTR | 1080 |
Homo sapiens | Primates | EEF2 | EEF2 | ncbigene_symbol | EEF2 | 1938 |
Homo sapiens | Primates | MTOR, | MTOR | ncbigene_symbol | MTOR | 2475 |
Word | Match | MeSH | Name | ChEBI |
---|---|---|---|---|
Fatty acid | Fatty Acids | mesh:D005227 | fatty acid | chebi:35366 |
Glucose | Glucose | mesh:D005947 | D-glucopyranose | chebi:4167 |
Disease mentions
Word | Match | MeSH | Name | DOID |
---|