Proposed role for AMPK in the kidney in coupling catabolic pathways requiring ATP hydrolysis (primarily sodium transport) with metabolic pathways leading to ATP synthesis (primarily fatty acid and glucose oxidation)

Proposed role for AMPK in the kidney in coupling catabolic pathways requiring ATP hydrolysis (primarily sodium transport) with metabolic pathways leading to ATP synthesis (primarily fatty acid and glucose oxidation). +, Activating pathway; −, inhibitory pathway.
Proposed role for AMPK in the kidney in coupling catabolic pathways requiring ATP hydrolysis (primarily sodium transport) with metabolic pathways leading to ATP synthesis (primarily fatty acid and glucose oxidation)

Publication

Role of the energy sensor AMP-activated protein kinase in renal physiology and disease. (2010) Kenneth R. Hallows, et al. Am J Physiol Renal Physiol. 2010 May;298(5):F1067-F1077. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Drosophila melanogaster Invertebrates Na NA ncbigene_symbol na 45338
Drosophila melanogaster Invertebrates ATP ATP ncbigene_synonym ATPsynbeta 43829
Drosophila melanogaster Invertebrates ATP ATP ncbigene_synonym Atpalpha 48971
Drosophila melanogaster Invertebrates AMPK AMPK ncbigene_synonym SNF4Agamma 42515
Drosophila melanogaster Invertebrates AMPK AMPK ncbigene_synonym AMPKalpha 43904
Drosophila melanogaster Invertebrates ACC ACC ncbigene_symbol ACC 35761
Drosophila melanogaster Invertebrates ACC ACC ncbigene_synonym tacc 40589
Drosophila melanogaster Invertebrates ACC ACC ncbigene_synonym acclinal-wing 247733
Drosophila melanogaster Invertebrates CFTR CFTR ncbigene_symbol Cftr 42928
Drosophila melanogaster Invertebrates NKCC NKCC ncbigene_symbol NKCC 40663
Drosophila melanogaster Invertebrates NKCC NKCC ncbigene_synonym Ncc69 39410
Drosophila melanogaster Invertebrates EEF2 EEF2 ncbigene_symbol eEF2 35422
Drosophila melanogaster Invertebrates EEF2 EEF2 ncbigene_synonym CG4849 43358
Drosophila melanogaster Invertebrates MTOR, MTOR ncbigene_symbol Mtor 36264
Drosophila melanogaster Invertebrates MTOR, MTOR ncbigene_synonym Tor 47396
Homo sapiens Primates ATP ATP ncbigene_synonym ATP8A2 51761
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAA1 5562
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAA2 5563
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAB1 5564
Homo sapiens Primates AMPK AMPK famplex_relations PRKAB2 5565
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG1 5571
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG2 51422
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG3 53632
Homo sapiens Primates ACC ACC ncbigene_synonym ACACA 31
Homo sapiens Primates ACC ACC ncbigene_synonym BMS1 9790
Homo sapiens Primates ACC ACC famplex_relations ACACB 32
Homo sapiens Primates CFTR CFTR ncbigene_symbol CFTR 1080
Homo sapiens Primates EEF2 EEF2 ncbigene_symbol EEF2 1938
Homo sapiens Primates MTOR, MTOR ncbigene_symbol MTOR 2475

Chemical mentions

Word Match MeSH Name ChEBI
Fatty acid Fatty Acids mesh:D005227 fatty acid chebi:35366
Glucose Glucose mesh:D005947 D-glucopyranose chebi:4167

Disease mentions

Word Match MeSH Name DOID