Class IA PI3K signalling pathway

The class IA PI3K signalling pathway
Class IA PI3K signalling pathway
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Publication

Phosphatidylinositol 3-kinase (PI3K) pathway activation in bladder cancer. (2009) Margaret A. Knowles, et al. Cancer Metastasis Rev. 2009 Dec;28(3-4):305-316. Figure: F1.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates p85 P85 ncbigene_synonym PIK3R1 5295
Homo sapiens Primates p85 P85 ncbigene_synonym PIK3R2 5296
Homo sapiens Primates p85 P85 ncbigene_synonym ARHGEF7 8874
Homo sapiens Primates p85 P85 ncbigene_synonym CBFA2T2 9139
Homo sapiens Primates p85 P85 ncbigene_synonym PPP1R13B 23368
Homo sapiens Primates p85 P85 ncbigene_synonym PPP1R12C 54776
Homo sapiens Primates PTEN PTEN ncbigene_symbol PTEN 5728
Homo sapiens Primates PDK1 PDK1 ncbigene_symbol PDK1 5163
Homo sapiens Primates PDK1 PDK1 ncbigene_synonym PDPK1 5170
Homo sapiens Primates p110a P110A ncbigene_synonym PIK3CA 5290
Homo sapiens Primates RAS RAS famplex_relations KRAS 3845
Homo sapiens Primates RAS RAS famplex_relations HRAS 3265
Homo sapiens Primates RAS RAS famplex_relations NRAS 4893
Homo sapiens Primates PI3 PI3 ncbigene_symbol PI3 5266
Homo sapiens Primates AKT AKT ncbigene_synonym AKT1 207
Homo sapiens Primates AKT AKT famplex_relations AKT2 208
Homo sapiens Primates AKT AKT famplex_relations AKT3 10000
Homo sapiens Primates TORC2 TORC2 ncbigene_synonym CRTC2 200186
Homo sapiens Primates RAF RAF ncbigene_synonym ZHX2 22882
Homo sapiens Primates RAF RAF famplex_relations ARAF 369
Homo sapiens Primates RAF RAF famplex_relations BRAF 673
Homo sapiens Primates RAF RAF famplex_relations RAF1 5894
Homo sapiens Primates MEK MEK ncbigene_synonym MAP2K7 5609
Homo sapiens Primates MEK MEK famplex_relations MAP2K1 5604
Homo sapiens Primates MEK MEK famplex_relations MAP2K2 5605
Homo sapiens Primates TSC2 TSC2 ncbigene_symbol TSC2 7249
Homo sapiens Primates TSC1 TSC1 ncbigene_symbol TSC1 7248
Homo sapiens Primates TSC1 TSC1 ncbigene_synonym CCL26 10344
Homo sapiens Primates ERK ERK ncbigene_synonym EPHB2 2048
Homo sapiens Primates ERK ERK ncbigene_synonym MAPK1 5594
Homo sapiens Primates ERK ERK famplex_relations MAPK3 5595
Homo sapiens Primates [AMP] AMP ncbigene_synonym APRT 353
Homo sapiens Primates [AMP] AMP ncbigene_synonym MFAP1 4236
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAA1 5562
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAA2 5563
Homo sapiens Primates AMPK AMPK ncbigene_synonym PRKAB1 5564
Homo sapiens Primates AMPK AMPK famplex_relations PRKAB2 5565
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG1 5571
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG2 51422
Homo sapiens Primates AMPK AMPK famplex_relations PRKAG3 53632
Homo sapiens Primates RHEB RHEB ncbigene_symbol RHEB 6009
Homo sapiens Primates RHEB RHEB ncbigene_synonym RHEBP1 6008
Homo sapiens Primates FNIP1 FNIP1 ncbigene_symbol FNIP1 96459
Homo sapiens Primates LKB1 LKB1 ncbigene_synonym STK11 6794
Homo sapiens Primates FLCN FLCN ncbigene_symbol FLCN 201163
Homo sapiens Primates MTOR MTOR ncbigene_symbol MTOR 2475
Homo sapiens Primates TORC1 TORC1 ncbigene_synonym CRTC1 23373
Drosophila melanogaster Invertebrates RTK RTK ncbigene_synonym Tie 38559
Drosophila melanogaster Invertebrates RTK RTK ncbigene_synonym Ras85D 41140
Drosophila melanogaster Invertebrates RTK RTK ncbigene_synonym InR 42549
Drosophila melanogaster Invertebrates p85 P85 ncbigene_synonym Myb 32543
Drosophila melanogaster Invertebrates p85 P85 ncbigene_synonym Pi3K21B 33203
Drosophila melanogaster Invertebrates p85 P85 ncbigene_synonym Taf5 47900
Drosophila melanogaster Invertebrates PTEN PTEN ncbigene_symbol Pten 43991
Drosophila melanogaster Invertebrates PDK1 PDK1 ncbigene_symbol Pdk1 38017
Drosophila melanogaster Invertebrates RAS RAS ncbigene_symbol ras 43873
Drosophila melanogaster Invertebrates RAS RAS ncbigene_synonym Ras64B 38494
Drosophila melanogaster Invertebrates AKT AKT ncbigene_symbol Akt 41957
Drosophila melanogaster Invertebrates TORC2 TORC2 ncbigene_synonym Crtc 39970
Drosophila melanogaster Invertebrates RAF RAF ncbigene_symbol Raf 31221
Drosophila melanogaster Invertebrates MEK MEK ncbigene_synonym Dsor1 31872
Drosophila melanogaster Invertebrates MEK MEK ncbigene_synonym Mtk 36708
Drosophila melanogaster Invertebrates TSC2 TSC2 ncbigene_synonym gig 40201
Drosophila melanogaster Invertebrates TSC1 TSC1 ncbigene_symbol Tsc1 42862
Drosophila melanogaster Invertebrates ERK ERK ncbigene_synonym Erk7 31877
Drosophila melanogaster Invertebrates ERK ERK ncbigene_synonym rl 3354888
Drosophila melanogaster Invertebrates [AMP] AMP ncbigene_synonym Amph 36383
Drosophila melanogaster Invertebrates AMPK AMPK ncbigene_synonym SNF4Agamma 42515
Drosophila melanogaster Invertebrates AMPK AMPK ncbigene_synonym AMPKalpha 43904
Drosophila melanogaster Invertebrates cycle CYCLE ncbigene_synonym CycE 34924
Drosophila melanogaster Invertebrates cycle CYCLE ncbigene_synonym cyc 40162
Drosophila melanogaster Invertebrates RHEB RHEB ncbigene_symbol Rheb 117332
Drosophila melanogaster Invertebrates LKB1 LKB1 ncbigene_symbol Lkb1 41673
Drosophila melanogaster Invertebrates MTOR MTOR ncbigene_symbol Mtor 36264
Drosophila melanogaster Invertebrates MTOR MTOR ncbigene_synonym Tor 47396

Chemical mentions

Word Match MeSH Name ChEBI
Ser Serine mesh:D012694 L-serine chebi:17115

Disease mentions

Word Match MeSH Name DOID
Cancer NA
Cardiomyopathy NA
Lung cancer NA
Noonan syndrome NA