Viral infection elicits a variety of antiviral cellular responses

Viral infection elicits a variety of antiviral cellular responses. Following viral infection, viral pathogen-associated molecular patterns are detected through both TLR and RIG pathways as described in the text. Following the activation of each pathway, signals are relayed to interferon regulatory factors and NF-κB, leading to their translocation from the cytoplasm into the nucleus. Upon arrival in the nucleus, they activate the transcription of a variety of antiviral mediators that limit viral replication and spread.

Publication

Pharmacologic and Chemical Adjuvants in Tumor Virotherapy. () Christopher Alvarez-Breckenridge, et al. Chem Rev. ;109(7):3125-3140. Figure: F2. All organisms Rattus norvegicus Equus caballus Homo sapiens Danio rerio

Disease mentions