Signaling pathways downstream of HVEM, LIGHT, and their binding partners are shown

Signaling pathways downstream of HVEM, LIGHT, and their binding partners are shown. Hypothetical pathways are shown with a question mark. Signaling downstream of the LTβR activates the alternative NF-κB pathway that acts through the NF-κB inducing kinase (NIK)
Signaling pathways downstream of HVEM, LIGHT, and their binding partners are shown
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Publication

Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners. () Marcos W. Steinberg, et al. Semin Immunopathol. ;31(2):207-221. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates TCR TCR ncbigene_synonym TRBV20OR9-2 6962
Homo sapiens Primates TCR TCR famplex_relations TRA 6955
Homo sapiens Primates TCR TCR famplex_relations TRB 6957
Homo sapiens Primates TCR TCR famplex_relations TRD 6964
Homo sapiens Primates TCR TCR famplex_relations TRG 6965
Homo sapiens Primates BCR BCR ncbigene_symbol BCR 613
Homo sapiens Primates BCR BCR ncbigene_synonym RN7SL263P 106480993
Homo sapiens Primates ERK ERK ncbigene_synonym EPHB2 2048
Homo sapiens Primates ERK ERK ncbigene_synonym MAPK1 5594
Homo sapiens Primates ERK ERK famplex_relations MAPK3 5595
Homo sapiens Primates BTLA BTLA ncbigene_symbol BTLA 151888
Homo sapiens Primates SHP2 SHP2 ncbigene_synonym PTPN11 5781
Homo sapiens Primates SHP SHP ncbigene_synonym NR0B2 8431
Homo sapiens Primates SHP-1 SHP-1 ncbigene_synonym PTPN6 5777
Homo sapiens Primates LIGHT LIGHT ncbigene_synonym TNFSF14 8740
Homo sapiens Primates GRB2 GRB2 ncbigene_symbol GRB2 2885
Homo sapiens Primates CD160 CD160 ncbigene_symbol CD160 11126
Homo sapiens Primates HVEM HVEM ncbigene_synonym TNFRSF14 8764
Homo sapiens Primates TRAF3 TRAF3 ncbigene_symbol TRAF3 7187
Homo sapiens Primates TRAF2 TRAF2 ncbigene_symbol TRAF2 7186
Homo sapiens Primates TRAF2 TRAF2 ncbigene_synonym TANK 10010
Homo sapiens Primates TRAF? TRAF famplex_relations TRAF1 7185
Homo sapiens Primates TRAF? TRAF famplex_relations TRAF4 9618
Homo sapiens Primates TRAF? TRAF famplex_relations TRAF5 7188
Homo sapiens Primates TRAF? TRAF famplex_relations TRAF6 7189
Homo sapiens Primates TRAF? TRAF famplex_relations TRAF7 84231
Homo sapiens Primates ASK-1 ASK1 ncbigene_synonym MAP3K5 4217
Homo sapiens Primates IKK IKK famplex_relations CHUK 1147
Homo sapiens Primates IKK IKK famplex_relations IKBKB 3551
Homo sapiens Primates IKK IKK famplex_relations IKBKG 8517
Homo sapiens Primates IKK IKK famplex_relations IKBKE 9641
Homo sapiens Primates IKK IKK famplex_relations TBK1 29110
Homo sapiens Primates Caspases CASPASE famplex_relations CASP1 834
Homo sapiens Primates Caspases CASPASE famplex_relations CASP2 835
Homo sapiens Primates Caspases CASPASE famplex_relations CASP4 837
Homo sapiens Primates Caspases CASPASE famplex_relations CASP5 838
Homo sapiens Primates Caspases CASPASE famplex_relations CASP6 839
Homo sapiens Primates Caspases CASPASE famplex_relations CASP8 841
Homo sapiens Primates Caspases CASPASE famplex_relations CASP9 842
Homo sapiens Primates Caspases CASPASE famplex_relations CASP10 843
Homo sapiens Primates Caspases CASPASE famplex_relations CASP12 100506742
Homo sapiens Primates Caspases CASPASE famplex_relations CASP14 23581
Homo sapiens Primates Caspases CASPASE famplex_relations CASP3 836
Homo sapiens Primates Caspases CASPASE famplex_relations CASP7 840
Homo sapiens Primates NEB NEB ncbigene_symbol NEB 4703

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID