Overall sketch of the two IPP/DMAPP producing pathways and their intracellular localization in plants

Overall sketch of the two IPP/DMAPP producing pathways and their intracellular localization in plants. Arrows indicate the overall pathway; many intermediates and additional substrates such as ATP and NADPH are omitted. The possible crosstalk between pathways is also marked with arrows. GPP: Geranyl diphosphate (C10), FPP: Farnesyl diphosphate (C15), GGPP: Geranylgeranyl diphosphate (C20).,
Overall sketch of the two IPP/DMAPP producing pathways and their intracellular localization in plants

Publication

Perspectives on Using Physcomitrella Patens as an Alternative Production Platform for Thapsigargin and Other Terpenoid Drug Candidates. (2009) Henrik Toft Simonsen, et al. Perspect Medicin Chem. 2009;3:1-6. Figure: F1.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Drosophila melanogaster Invertebrates CoA COA ncbigene_symbol Coa 248135
Drosophila melanogaster Invertebrates HMG HMG ncbigene_synonym Hmgcr 42803
Drosophila melanogaster Invertebrates HMG HMG ncbigene_synonym Dsp1 117294
Drosophila melanogaster Invertebrates IPP IPP ncbigene_symbol Ipp 41701
Drosophila melanogaster Invertebrates IPP IPP ncbigene_synonym CG9784 32629
Drosophila melanogaster Invertebrates IPP IPP ncbigene_synonym CG9426 34719
Drosophila melanogaster Invertebrates IPP IPP ncbigene_synonym CG6805 36911
Drosophila melanogaster Invertebrates IPP IPP ncbigene_synonym Synj 37517
Drosophila melanogaster Invertebrates IPP IPP ncbigene_synonym INPP5E 39404
Drosophila melanogaster Invertebrates IPP IPP ncbigene_synonym 5PtaseI 326119
Drosophila melanogaster Invertebrates GPP GPP ncbigene_symbol gpp 40793

Chemical mentions

Word Match MeSH Name ChEBI
Squalane NA mesh:C019556
DMAPP NA mesh:C043060
Diterpenes NA mesh:D004224
Glyceraldehyde Glyceraldehyde mesh:D005985 glyceraldehyde chebi:5445
3-phosphate NA mesh:D010710
Sterols Sterols mesh:D013261 sterol chebi:15889
Monoterpenes NA mesh:D039821

Disease mentions

Word Match MeSH Name DOID