Androgen receptor pathway
Androgen receptor pathway. The annotations of symbols and lines are the same as Figure 4. This figure suggests at HR stage, the aberrances in AR signalling can be manifested in two steps. The first step is the activation of AR including its transport into nucleus without androgen induction, and the second step is the regulation of nuclear coactivators and repressors for AR's transactivation.
Publication
A stochastic model for identifying differential gene pair co-expression patterns in prostate cancer progression. (2009) Wen Juan Mo, et al. BMC Genomics. 2009;10:340-340. Figure: F6.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | SVIL | SVIL | ncbigene_symbol | SVIL | 6840 |
| Homo sapiens | Primates | BAG1 | BAG1 | ncbigene_symbol | BAG1 | 573 |
| Homo sapiens | Primates | AR | AR | ncbigene_symbol | AR | 367 |
| Homo sapiens | Primates | HSD11B1 | HSD11B1 | ncbigene_symbol | HSD11B1 | 3290 |
| Homo sapiens | Primates | PLAGL1 | PLAGL1 | ncbigene_symbol | PLAGL1 | 5325 |
| Homo sapiens | Primates | PTGS1 | PTGS1 | ncbigene_symbol | PTGS1 | 5742 |
| Danio rerio | Vertebrates | SVIL | SVIL | ncbigene_synonym | svila | 30112 |
| Danio rerio | Vertebrates | BAG1 | BAG1 | ncbigene_symbol | bag1 | 558108 |
| Danio rerio | Vertebrates | AR | AR | ncbigene_symbol | ar | 100005148 |
| Danio rerio | Vertebrates | PTGS1 | PTGS1 | ncbigene_symbol | ptgs1 | 246226 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| Cortisone | Cortisone | mesh:D003348 | cortisone | chebi:16962 |
| Cortisol | Hydrocortisone | mesh:D006854 | cortisol | chebi:17650 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|