Direct targets of WT1 identified in the Wnt signaling pathway

Direct targets of WT1 identified in the Wnt signaling pathway. Genes bound and regulated by WT1 are indicated in red bold. PPP3CB, a candidate WT1 direct target, is involved in noncanonical Wnt/Ca2+pathway (not shown here). Activation and repression by WT1 are shown with up and down arrows, respectively.
Direct targets of WT1 identified in the Wnt signaling pathway
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Publication

An integrated genome screen identifies the Wnt signaling pathway as a major target of WT1. (2009) Marianne K.-H. Kim, et al. Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11154-11159. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates Wnt WNT famplex_relations WNT1 7471
Homo sapiens Primates Wnt WNT famplex_relations WNT2 7472
Homo sapiens Primates Wnt WNT famplex_relations WNT2B 7482
Homo sapiens Primates Wnt WNT famplex_relations WNT3 7473
Homo sapiens Primates Wnt WNT famplex_relations WNT3A 89780
Homo sapiens Primates Wnt WNT famplex_relations WNT4 54361
Homo sapiens Primates Wnt WNT famplex_relations WNT6 7475
Homo sapiens Primates Wnt WNT famplex_relations WNT7A 7476
Homo sapiens Primates Wnt WNT famplex_relations WNT7B 7477
Homo sapiens Primates Wnt WNT famplex_relations WNT8A 7478
Homo sapiens Primates Wnt WNT famplex_relations WNT8B 7479
Homo sapiens Primates Wnt WNT famplex_relations WNT9A 7483
Homo sapiens Primates Wnt WNT famplex_relations WNT9B 7484
Homo sapiens Primates Wnt WNT famplex_relations WNT10A 80326
Homo sapiens Primates Wnt WNT famplex_relations WNT10B 7480
Homo sapiens Primates Wnt WNT famplex_relations WNT11 7481
Homo sapiens Primates Wnt WNT famplex_relations WNT16 51384
Homo sapiens Primates Wnt WNT famplex_relations WNT5A 7474
Homo sapiens Primates Wnt WNT famplex_relations WNT5B 81029
Homo sapiens Primates DACT1 DACT1 ncbigene_symbol DACT1 51339
Homo sapiens Primates CKle CKIE ncbigene_synonym CSNK1E 1454
Homo sapiens Primates B-catenin CTNNB1 ncbigene_symbol CTNNB1 1499
Homo sapiens Primates APC APC ncbigene_symbol APC 324
Homo sapiens Primates APC APC ncbigene_synonym PROC 5624
Homo sapiens Primates Axin AXIN ncbigene_synonym AXIN1 8312
Homo sapiens Primates Axin AXIN famplex_relations AXIN2 8313
Homo sapiens Primates TBL1X TBL1X ncbigene_symbol TBL1X 6907
Homo sapiens Primates BTrCP BTRCP ncbigene_synonym BTRC 8945
Homo sapiens Primates MAP MAP ncbigene_synonym SGSM3 27352
Homo sapiens Primates c-jun C-JUN ncbigene_synonym JUN 3725
Homo sapiens Primates C-myc C-MYC ncbigene_synonym MYC 4609
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA1 5682
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA2 5683
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA3 5684
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA4 5685
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA5 5686
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA6 5687
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA7 5688
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA8 143471
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB1 5689
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB10 5699
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB2 5690
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB3 5691
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB4 5692
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB5 5693
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB6 5694
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB7 5695
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB8 5696
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB9 5698
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC1 5700
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC2 5701
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC3 5702
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC4 5704
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC5 5705
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC6 5706
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD1 5707
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD10 5716
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD11 5717
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD12 5718
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD13 5719
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD14 10213
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD2 5708
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD3 5709
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD4 5710
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD5 5711
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD6 9861
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD7 5713
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD8 5714
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD9 5715
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSME1 5720
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSME2 5721
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSME3 10197
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMF1 9491
Homo sapiens Primates Proteasome PROTEASOME famplex_relations SEM1 7979
Homo sapiens Primates Proteasome PROTEASOME famplex_relations USP5 8078
Homo sapiens Primates NLK NLK ncbigene_symbol NLK 51701
Homo sapiens Primates NLK NLK ncbigene_synonym GPI 2821
Homo sapiens Primates TAK1 TAK1 ncbigene_synonym MAP3K7 6885
Homo sapiens Primates TAK1 TAK1 ncbigene_synonym NR2C2 7182

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Cancer NA