Network contains downregulated genes and identified around NFKB gene

Network contains downregulated genes and identified around NFKB gene. Top functions of the genes were related to cellular assembly and organization, connective tissue development and function, neurological disease. Node (gene) and edge (gene relationship) symbols were described in the bottom part of the figure. The intensity of the node color (green) indicated the degree of downregulation. Genes in uncolored notes were not identified as differentially expressed in our experiment and were integrated into the computationally generated networks on the basis of the evidence stored in the IPA knowledge memory indicating a relevance to this network. The node shapes denote enzymes, phosphatases, kinases, peptidases, G-protein coupled receptor, transmembrane receptor, cytokines, growth factor, ion channel, transporter, translation factor, nuclear receptor, transcription factor and other.

Publication

Gene network and canonical pathway analysis in prostate cancer: a microarray study. (2008) Hakan Savli, et al. Exp Mol Med. 2008 Apr 30;40(2):176-185. Figure: F2. Homo sapiens

Disease mentions