Schematic diagrams depicting the Wnt signaling pathways

Schematic diagrams depicting the Wnt signaling pathways. The canonical Wnt signaling pathway (left 2) and planar cell polarity pathway (right) are shown. Wnts, represented by yellow circles represent a large family of signaling molecules. In general, Wnts 1, 3a, 8 and 8b induce the canonical Wnt signaling pathway while Wnts 5a and 11 favor the non-canonical pathway; however, significant cross talk between these pathways has been observed. There are a number of other Wnt signaling pathways that have not been described here as their role in skin appendages is yet to be established. More detailed views are presented elsewhere.,
Schematic diagrams depicting the Wnt signaling pathways
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Publication

Wnt signaling in skin organogenesis. (2008) Randall B Widelitz. Organogenesis. 2008 Apr-Jun;4(2):123-133. Figure: F1.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Drosophila melanogaster Invertebrates WnD WND ncbigene_symbol wnd 40143
Drosophila melanogaster Invertebrates Wnt WNT ncbigene_synonym Wnt5 32838
Drosophila melanogaster Invertebrates Wnt WNT ncbigene_synonym Wnt4 34007
Drosophila melanogaster Invertebrates Wnt WNT ncbigene_synonym wg 34009
Drosophila melanogaster Invertebrates Wnt WNT ncbigene_synonym Wnt2 35975
Drosophila melanogaster Invertebrates LRP5/6 LRP5/6 ncbigene_synonym arr 44279
Drosophila melanogaster Invertebrates Fz FZ ncbigene_symbol fz 45307
Drosophila melanogaster Invertebrates PP2A PP2A ncbigene_synonym wrd 42169
Drosophila melanogaster Invertebrates PP2A PP2A ncbigene_synonym wdb 43312
Drosophila melanogaster Invertebrates PP2A PP2A ncbigene_synonym mts 45959
Drosophila melanogaster Invertebrates PP2A PP2A ncbigene_synonym tws 47877
Drosophila melanogaster Invertebrates PP2A PP2A ncbigene_synonym Pp2A-29B 2768940
Drosophila melanogaster Invertebrates B-cat B-CAT ncbigene_synonym arm 31151
Drosophila melanogaster Invertebrates Axin AXIN ncbigene_synonym Axn 43565
Drosophila melanogaster Invertebrates Dvl DVL ncbigene_synonym dsh 32078
Drosophila melanogaster Invertebrates Actin ACTIN ncbigene_synonym Act5C 31521
Drosophila melanogaster Invertebrates Actin ACTIN ncbigene_synonym Act42A 35526
Drosophila melanogaster Invertebrates Actin ACTIN ncbigene_synonym Act57B 37368
Drosophila melanogaster Invertebrates Actin ACTIN ncbigene_synonym Act79B 40444
Drosophila melanogaster Invertebrates Actin ACTIN ncbigene_synonym Act88F 41885
Drosophila melanogaster Invertebrates Actin ACTIN ncbigene_synonym Act87E 48632
Drosophila melanogaster Invertebrates PKC PKC ncbigene_synonym inaC 36897
Drosophila melanogaster Invertebrates PKC PKC ncbigene_synonym Pkc98E 43428
Drosophila melanogaster Invertebrates PKC PKC ncbigene_synonym aPKC 47594
Drosophila melanogaster Invertebrates PKC PKC ncbigene_synonym Pkc53E 48311
Drosophila melanogaster Invertebrates JNK JNK ncbigene_synonym bsk 44801
Drosophila melanogaster Invertebrates Lefs/TCF TCF ncbigene_synonym pan 43769
Drosophila melanogaster Invertebrates and AND ncbigene_synonym CkIIbeta 32132
Drosophila melanogaster Invertebrates and AND ncbigene_synonym Andorra 32798
Drosophila melanogaster Invertebrates and AND ncbigene_synonym Anp 43595
Drosophila melanogaster Invertebrates and AND ncbigene_synonym Acam 44913
Homo sapiens Primates WnD WND ncbigene_synonym ATP7B 540
Homo sapiens Primates WID WID ncbigene_synonym CXXC5 51523
Homo sapiens Primates Wnt WNT famplex_relations WNT1 7471
Homo sapiens Primates Wnt WNT famplex_relations WNT2 7472
Homo sapiens Primates Wnt WNT famplex_relations WNT2B 7482
Homo sapiens Primates Wnt WNT famplex_relations WNT3 7473
Homo sapiens Primates Wnt WNT famplex_relations WNT3A 89780
Homo sapiens Primates Wnt WNT famplex_relations WNT4 54361
Homo sapiens Primates Wnt WNT famplex_relations WNT6 7475
Homo sapiens Primates Wnt WNT famplex_relations WNT7A 7476
Homo sapiens Primates Wnt WNT famplex_relations WNT7B 7477
Homo sapiens Primates Wnt WNT famplex_relations WNT8A 7478
Homo sapiens Primates Wnt WNT famplex_relations WNT8B 7479
Homo sapiens Primates Wnt WNT famplex_relations WNT9A 7483
Homo sapiens Primates Wnt WNT famplex_relations WNT9B 7484
Homo sapiens Primates Wnt WNT famplex_relations WNT10A 80326
Homo sapiens Primates Wnt WNT famplex_relations WNT10B 7480
Homo sapiens Primates Wnt WNT famplex_relations WNT11 7481
Homo sapiens Primates Wnt WNT famplex_relations WNT16 51384
Homo sapiens Primates Wnt WNT famplex_relations WNT5A 7474
Homo sapiens Primates Wnt WNT famplex_relations WNT5B 81029
Homo sapiens Primates LRP5/6 LRP6 ncbigene_symbol LRP6 4040
Homo sapiens Primates LRP5/6 LRP5 ncbigene_symbol LRP5 4041
Homo sapiens Primates PP2A PP2A ncbigene_synonym PTPA 5524
Homo sapiens Primates Axin AXIN ncbigene_synonym AXIN1 8312
Homo sapiens Primates Axin AXIN famplex_relations AXIN2 8313
Homo sapiens Primates Dvl DVL ncbigene_synonym DVL1 1855
Homo sapiens Primates Dvl DVL ncbigene_synonym DVL1P1 8215
Homo sapiens Primates Dvl DVL famplex_relations DVL2 1856
Homo sapiens Primates Dvl DVL famplex_relations DVL3 1857
Homo sapiens Primates Dvl DV1 ncbigene_synonym IFT81 28981
Homo sapiens Primates Actin ACTIN famplex_relations ACTA1 58
Homo sapiens Primates Actin ACTIN famplex_relations ACTA2 59
Homo sapiens Primates Actin ACTIN famplex_relations ACTB 60
Homo sapiens Primates Actin ACTIN famplex_relations ACTC1 70
Homo sapiens Primates Actin ACTIN famplex_relations ACTG1 71
Homo sapiens Primates Actin ACTIN famplex_relations ACTG2 72
Homo sapiens Primates PKC PKC ncbigene_synonym PRRT2 112476
Homo sapiens Primates PKC PKC famplex_relations PRKCA 5578
Homo sapiens Primates PKC PKC famplex_relations PRKCB 5579
Homo sapiens Primates PKC PKC famplex_relations PRKCD 5580
Homo sapiens Primates PKC PKC famplex_relations PRKCE 5581
Homo sapiens Primates PKC PKC famplex_relations PRKCG 5582
Homo sapiens Primates PKC PKC famplex_relations PRKCH 5583
Homo sapiens Primates PKC PKC famplex_relations PRKCI 5584
Homo sapiens Primates PKC PKC famplex_relations PRKCQ 5588
Homo sapiens Primates PKC PKC famplex_relations PRKCZ 5590
Homo sapiens Primates PKC PKC famplex_relations PRKD3 23683
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA1 5682
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA2 5683
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA3 5684
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA4 5685
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA5 5686
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA6 5687
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA7 5688
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMA8 143471
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB1 5689
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB10 5699
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB2 5690
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB3 5691
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB4 5692
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB5 5693
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB6 5694
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB7 5695
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB8 5696
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMB9 5698
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC1 5700
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC2 5701
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC3 5702
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC4 5704
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC5 5705
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMC6 5706
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD1 5707
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD10 5716
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD11 5717
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD12 5718
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD13 5719
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD14 10213
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD2 5708
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD3 5709
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD4 5710
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD5 5711
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD6 9861
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD7 5713
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD8 5714
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMD9 5715
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSME1 5720
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSME2 5721
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSME3 10197
Homo sapiens Primates Proteasome PROTEASOME famplex_relations PSMF1 9491
Homo sapiens Primates Proteasome PROTEASOME famplex_relations SEM1 7979
Homo sapiens Primates Proteasome PROTEASOME famplex_relations USP5 8078
Homo sapiens Primates JNK JNK ncbigene_synonym MAPK8 5599
Homo sapiens Primates JNK JNK famplex_relations MAPK9 5601
Homo sapiens Primates JNK JNK famplex_relations MAPK10 5602
Homo sapiens Primates Lefs/TCF TCF ncbigene_synonym HNF4A 3172

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Cancer NA