The signaling pathway of Type II, FasL signaling-induced apoptosis, adapted from Bagci et al

The signaling pathway of Type II, FasL signaling-induced apoptosis, adapted from Bagci et al. (). Broken arrows represent translocation reactions. Double-headed arrows represent reversible reactions with forward and reversible reactions labeled as kip and kim, respectively, throughout the text. Degradation and production parameters are denoted with a μ and a G, respectively, preceding the species label throughout the text.
The signaling pathway of Type II, FasL signaling-induced apoptosis, adapted from Bagci et al

Publication

Identifying Fragilities in Biochemical Networks: Robust Performance Analysis of Fas Signaling-Induced Apoptosis. (2008) Jason E. Shoemaker, et al. Biophys J. 2008 Sep 15;95(6):2610-2623. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates (Fasl FASL ncbigene_synonym FASLG 356
Homo sapiens Primates (Fasl FAS1 ncbigene_synonym FAS 355
Homo sapiens Primates casp3 CASP3 ncbigene_symbol CASP3 836
Homo sapiens Primates Bid BID ncbigene_symbol BID 637
Homo sapiens Primates casp8 CASP8 ncbigene_symbol CASP8 841
Homo sapiens Primates IAP IAP ncbigene_synonym ALPI 248
Homo sapiens Primates IAP IAP ncbigene_synonym ALPP 250
Homo sapiens Primates IAP IAP ncbigene_synonym CD47 961
Homo sapiens Primates IAP IAP ncbigene_synonym IAPP 3375
Homo sapiens Primates IAP IAP ncbigene_synonym MAGT1 84061
Homo sapiens Primates casp9 CASP9 ncbigene_symbol CASP9 842
Homo sapiens Primates Bcl-2 BCL-2 ncbigene_synonym BCL2 596
Homo sapiens Primates Bax BAX ncbigene_symbol BAX 581
Homo sapiens Primates pro3 PRO3 ncbigene_synonym PYCR1 5831
Homo sapiens Primates Kab KAB ncbigene_synonym CEP170 9859
Homo sapiens Primates Apaf-1 APAF-1 ncbigene_synonym APAF1 317
Homo sapiens Primates apop APOP ncbigene_synonym COA8 84334

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID