The Aedes aegypti Toll Pathway Controls Dengue Virus Infection

Red color indicates infection responsive up-regulation and green color indicate infection responsive down-regulation. Non-colored gene boxes indicate lack of infection responsive regulation. The pathway was built with GenMapp software based on the immunogenomics prediction by Waterhouse et al 2007.
The Aedes aegypti Toll Pathway Controls Dengue Virus Infection
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Publication

The Aedes aegypti Toll Pathway Controls Dengue Virus Infection. (2008) Zhiyong Xi, et al. PLoS Pathog. 2008 Jul;4(7):e1000098. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Drosophila melanogaster Invertebrates PGRPLA PGRPLA ncbigene_symbol PGRP-LA 39062
Drosophila melanogaster Invertebrates PGRPLE PGRPLE ncbigene_symbol PGRP-LE 32534
Drosophila melanogaster Invertebrates PGRPLB PGRPLB ncbigene_symbol PGRP-LB 41379
Drosophila melanogaster Invertebrates SPZ2 SPZ2 ncbigene_synonym NT1 38558
Drosophila melanogaster Invertebrates SPZ4 SPZ4 ncbigene_symbol spz4 34572
Drosophila melanogaster Invertebrates PGRPLC PGRPLC ncbigene_symbol PGRP-LC 39063
Drosophila melanogaster Invertebrates SPZ5 SPZ5 ncbigene_symbol spz5 38350
Drosophila melanogaster Invertebrates PGRPLD PGRPLD ncbigene_symbol PGRP-LD 3771920
Drosophila melanogaster Invertebrates SPZ6 SPZ6 ncbigene_symbol spz6 37956
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym Toll-4 34235
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym Tehao 34761
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym Toll-7 37272
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym 18w 37277
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym Toll-6 39663
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym Toll-9 40245
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym MstProx 40890
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym Tl 43222
Drosophila melanogaster Invertebrates TOLL TOLL ncbigene_synonym Tollo 44497
Drosophila melanogaster Invertebrates IMD IMD ncbigene_symbol imd 44339
Drosophila melanogaster Invertebrates MYD88 MYD88 ncbigene_symbol Myd88 35956
Drosophila melanogaster Invertebrates FADD FADD ncbigene_symbol Fadd 42594
Drosophila melanogaster Invertebrates TUB TUB ncbigene_symbol tub 40554
Drosophila melanogaster Invertebrates TUB TUB ncbigene_synonym betaTub56D 37238
Drosophila melanogaster Invertebrates TUB TUB ncbigene_synonym betaTub60D 37888
Drosophila melanogaster Invertebrates TUB TUB ncbigene_synonym alphaTub67C 39130
Drosophila melanogaster Invertebrates TUB TUB ncbigene_synonym alphaTub84B 40848
Drosophila melanogaster Invertebrates TUB TUB ncbigene_synonym alphaTub84D 40904
Drosophila melanogaster Invertebrates TUB TUB ncbigene_synonym betaTub85D 41124
Drosophila melanogaster Invertebrates TUB TUB ncbigene_synonym alphaTub85E 41183
Drosophila melanogaster Invertebrates TUB TUB ncbigene_synonym betaTub97EF 43359
Drosophila melanogaster Invertebrates DREDD DREDD ncbigene_symbol Dredd 31011
Drosophila melanogaster Invertebrates PELLE PELLE ncbigene_synonym pll 43283
Drosophila melanogaster Invertebrates TAK1 TAK1 ncbigene_symbol Tak1 39659
Drosophila melanogaster Invertebrates IAP2 IAP2 ncbigene_synonym Diap2 36748
Drosophila melanogaster Invertebrates DPC DPC ncbigene_synonym PCB 36020
Drosophila melanogaster Invertebrates DPC DPC ncbigene_synonym Pc 40358
Drosophila melanogaster Invertebrates GAM GAM ncbigene_synonym pygo 43718
Drosophila melanogaster Invertebrates ATT ATT ncbigene_synonym AttC 36484
Drosophila melanogaster Invertebrates ATT ATT ncbigene_synonym AttA 36636
Drosophila melanogaster Invertebrates ATT ATT ncbigene_synonym AttB 36637
Drosophila melanogaster Invertebrates ATT ATT ncbigene_synonym AttD 42122
Drosophila melanogaster Invertebrates ATT ATT ncbigene_synonym DPCoAC 42429
Drosophila melanogaster Invertebrates ATT ATT ncbigene_synonym att-ORFB 2768673
Drosophila melanogaster Invertebrates CECA CECA ncbigene_synonym CecA1 43596
Drosophila melanogaster Invertebrates CECA CECA ncbigene_synonym CecA2 43597
Drosophila melanogaster Invertebrates CECB CECB ncbigene_symbol CecB 43598
Drosophila melanogaster Invertebrates CECC CECC ncbigene_symbol CecC 43599
Mus musculus Rodents IMD IMD ncbigene_synonym Adm2 223780
Mus musculus Rodents MYD88 MYD88 ncbigene_symbol Myd88 17874
Mus musculus Rodents FADD FADD ncbigene_symbol Fadd 14082
Mus musculus Rodents TUB TUB ncbigene_symbol Tub 22141
Mus musculus Rodents TAK1 TAK1 ncbigene_synonym Nr2c2 22026
Mus musculus Rodents TAK1 TAK1 ncbigene_synonym Map3k7 26409
Mus musculus Rodents IAP2 IAP2 ncbigene_symbol Iap2 108353
Mus musculus Rodents IAP2 IAP2 ncbigene_synonym Birc3 11796
Mus musculus Rodents IAP2 IAP2 ncbigene_synonym Birc2 11797
Mus musculus Rodents TH TH ncbigene_symbol Th 21823
Mus musculus Rodents IKK2 IKK2 ncbigene_synonym Ikbkb 16150
Mus musculus Rodents DEF1 DEF1 ncbigene_synonym Asap1 13196
Homo sapiens Primates TOLL TOLL ncbigene_synonym TLR4 7099
Homo sapiens Primates MYD88 MYD88 ncbigene_symbol MYD88 4615
Homo sapiens Primates FADD FADD ncbigene_symbol FADD 8772
Homo sapiens Primates TUB TUB ncbigene_symbol TUB 7275
Homo sapiens Primates PELLE PELLE ncbigene_synonym IRAK1 3654
Homo sapiens Primates TAK1 TAK1 ncbigene_synonym MAP3K7 6885
Homo sapiens Primates TAK1 TAK1 ncbigene_synonym NR2C2 7182
Homo sapiens Primates TH TH ncbigene_symbol TH 7054
Homo sapiens Primates IKK2 IKK2 ncbigene_synonym IKBKB 3551
Homo sapiens Primates GAM GAM ncbigene_synonym GLS 2744
Homo sapiens Primates DEF1 DEF1 ncbigene_synonym DEFA1 1667
Homo sapiens Primates DEF1 DEF1 ncbigene_synonym ZEB1 6935
Capra hircus Mammals MYD88 MYD88 ncbigene_symbol MYD88 102174883
Capra hircus Mammals FADD FADD ncbigene_symbol FADD 102170760
Capra hircus Mammals TUB TUB ncbigene_symbol TUB 102184640
Capra hircus Mammals TH TH ncbigene_symbol TH 102179849
Aedes aegypti Invertebrates GNBPB4 GNBPB4 ncbigene_synonym LOC5571588 5571588
Aedes aegypti Invertebrates GNBPA1 GNBPA1 ncbigene_synonym LOC5569420 5569420
Aedes aegypti Invertebrates GNBPA2 GNBPA2 ncbigene_synonym LOC5565422 5565422
Aedes aegypti Invertebrates GNBPB5 GNBPB5 ncbigene_synonym LOC5579191 5579191
Aedes aegypti Invertebrates GNBPB6 GNBPB6 ncbigene_synonym LOC5568698 5568698
Aedes aegypti Invertebrates GNBPB1 GNBPB1 ncbigene_synonym LOC5579192 5579192
Aedes aegypti Invertebrates GNBPB3 GNBPB3 ncbigene_synonym LOC5571589 5571589
Aedes aegypti Invertebrates CLIPB13A CLIPB13A ncbigene_synonym LOC5577660 5577660
Aedes aegypti Invertebrates CLIPB13B CLIPB13B ncbigene_synonym LOC5577659 5577659
Aedes aegypti Invertebrates PGRPLE PGRPLE ncbigene_synonym LOC5577250 5577250
Aedes aegypti Invertebrates PGRPLB PGRPLB ncbigene_synonym LOC5572949 5572949
Aedes aegypti Invertebrates PGRPS1 PGRPS1 ncbigene_synonym LOC5571998 5571998
Aedes aegypti Invertebrates SPZ2 SPZ2 ncbigene_synonym LOC5570525 5570525
Aedes aegypti Invertebrates SPZ1A| SPZ1A ncbigene_symbol Spz1A 5577953
Aedes aegypti Invertebrates SPZ4 SPZ4 ncbigene_synonym LOC5569768 5569768
Aedes aegypti Invertebrates PGRPLC PGRPLC ncbigene_synonym LOC5576901 5576901
Aedes aegypti Invertebrates SPZ3A SPZ3A ncbigene_synonym LOC5565708 5565708
Aedes aegypti Invertebrates SPZ5 SPZ5 ncbigene_synonym LOC5573010 5573010
Aedes aegypti Invertebrates SPZ1B SPZ1B ncbigene_symbol Spz1B 112552147
Aedes aegypti Invertebrates SPZ1C| SPZ1C ncbigene_symbol Spz1C 5577955
Aedes aegypti Invertebrates SPZ6 SPZ6 ncbigene_synonym LOC5575927 5575927
Aedes aegypti Invertebrates IMD IMD ncbigene_synonym LOC5572865 5572865
Aedes aegypti Invertebrates FADD FADD ncbigene_synonym LOC5573014 5573014
Aedes aegypti Invertebrates PELLE PELLE ncbigene_synonym LOC5568148 5568148
Aedes aegypti Invertebrates IAP2 IAP2 ncbigene_synonym LOC5568196 5568196
Aedes aegypti Invertebrates IKK2 IKK2 ncbigene_synonym LOC5576410 5576410
Aedes aegypti Invertebrates REL1B REL1B ncbigene_synonym LOC5568518 5568518
Aedes aegypti Invertebrates REL2 REL2 ncbigene_synonym LOC5569427 5569427
Aedes aegypti Invertebrates LYSC7B LYSC7B ncbigene_synonym LOC5579458 5579458
Aedes aegypti Invertebrates LYSC4 LYSC4 ncbigene_synonym LOC23687552 23687552
Aedes aegypti Invertebrates ATT ATT ncbigene_synonym LOC5578028 5578028
Aedes aegypti Invertebrates CECJ|DEFD DEFD ncbigene_synonym LOC5579095 5579095
Danio rerio Vertebrates MYD88 MYD88 ncbigene_symbol myd88 403145
Danio rerio Vertebrates FADD FADD ncbigene_symbol fadd 562317
Danio rerio Vertebrates TUB TUB ncbigene_symbol tub 568677
Danio rerio Vertebrates TH TH ncbigene_symbol th 30384
Danio rerio Vertebrates IKK2 IKK2 ncbigene_synonym ikbkb 563560

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID