MCF10A Pathway 1 affected by TFIIS knockdown

MCF10A Pathway 1 affected by TFIIS knockdown. The figure represents MCF10A pathways 1 derived from the Ingenuity® Systems program, which maintains a copyright on the image networks. Labeling of the network is similar to that of figure 8.
MCF10A Pathway 1 affected by TFIIS knockdown
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Publication

Knockdown of TFIIS by RNA silencing inhibits cancer cell proliferation and induces apoptosis. (2008) Kyle Hubbard, et al. BMC Cancer. 2008;8:133-133. Figure: F9.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates GPRC5A GPRC5A ncbigene_symbol GPRC5A 9052
Homo sapiens Primates IFIT3 IFIT3 ncbigene_symbol IFIT3 3437
Homo sapiens Primates BAMBI BAMBI ncbigene_symbol BAMBI 25805
Homo sapiens Primates IL15 IL15 ncbigene_symbol IL15 3600
Homo sapiens Primates TLE4 TLE4 ncbigene_symbol TLE4 7091
Homo sapiens Primates DDX18 DDX18 ncbigene_symbol DDX18 8886
Homo sapiens Primates MYST4 MYST4 ncbigene_synonym KAT6B 23522
Homo sapiens Primates CTSW CTSW ncbigene_symbol CTSW 1521
Homo sapiens Primates C6ORF108 C6ORF108 ncbigene_synonym DNPH1 10591
Homo sapiens Primates NKX2-8 NKX2-8 ncbigene_symbol NKX2-8 26257
Homo sapiens Primates HMGN2 HMGN2 ncbigene_symbol HMGN2 3151
Homo sapiens Primates MYC MYC ncbigene_symbol MYC 4609
Homo sapiens Primates MÝST3 MYST3 ncbigene_synonym KAT6A 7994
Homo sapiens Primates RBBP7 RBBP7 ncbigene_symbol RBBP7 5931
Homo sapiens Primates PERP PERP ncbigene_symbol PERP 64065
Homo sapiens Primates SS18 SS18 ncbigene_symbol SS18 6760
Homo sapiens Primates TP53 TP53 ncbigene_symbol TP53 7157
Homo sapiens Primates PPP1R15A PPP1R15A ncbigene_symbol PPP1R15A 23645
Homo sapiens Primates TNPO2 TNPO2 ncbigene_symbol TNPO2 30000
Homo sapiens Primates ARID4A ARID4A ncbigene_symbol ARID4A 5926
Homo sapiens Primates NPDC1 NPDC1 ncbigene_symbol NPDC1 56654
Homo sapiens Primates POLH POLH ncbigene_symbol POLH 5429
Homo sapiens Primates NFIC NFIC ncbigene_symbol NFIC 4782
Homo sapiens Primates NFIC NFIC ncbigene_synonym SMIM44 122405565
Rattus norvegicus Rodents GPRC5A GPRC5A ncbigene_symbol Gprc5a 312790
Rattus norvegicus Rodents IFIT3 IFIT3 ncbigene_symbol Ifit3 309526
Rattus norvegicus Rodents BAMBI BAMBI ncbigene_symbol Bambi 83837
Rattus norvegicus Rodents IL15 IL15 ncbigene_symbol Il15 25670
Rattus norvegicus Rodents TLE4 TLE4 ncbigene_symbol Tle4 25565
Rattus norvegicus Rodents DDX18 DDX18 ncbigene_symbol Ddx18 308490
Rattus norvegicus Rodents CTSW CTSW ncbigene_symbol Ctsw 293676
Rattus norvegicus Rodents C6ORF108 C6ORF108 ncbigene_synonym Dnph1 171047
Rattus norvegicus Rodents NKX2-8 NKX2-8 ncbigene_symbol Nkx2-8 299061
Rattus norvegicus Rodents HMGN2 HMGN2 ncbigene_symbol Hmgn2 114637
Rattus norvegicus Rodents MYC MYC ncbigene_symbol Myc 24577
Rattus norvegicus Rodents MÝST3 MYST3 ncbigene_synonym Kat6a 306571
Rattus norvegicus Rodents RBBP7 RBBP7 ncbigene_symbol Rbbp7 83712
Rattus norvegicus Rodents PERP PERP ncbigene_symbol Perp 292949
Rattus norvegicus Rodents SS18 SS18 ncbigene_symbol Ss18 361295
Rattus norvegicus Rodents TP53 TP53 ncbigene_symbol Tp53 24842
Rattus norvegicus Rodents PPP1R15A PPP1R15A ncbigene_symbol Ppp1r15a 171071
Rattus norvegicus Rodents TNPO2 TNPO2 ncbigene_symbol Tnpo2 304670
Rattus norvegicus Rodents ARID4A ARID4A ncbigene_symbol Arid4a 314205
Rattus norvegicus Rodents NPDC1 NPDC1 ncbigene_symbol Npdc1 296562
Rattus norvegicus Rodents POLH POLH ncbigene_symbol Polh 316235
Rattus norvegicus Rodents NFIC NFIC ncbigene_symbol Nfic 29228
Bos taurus Mammals GPRC5A GPRC5A ncbigene_symbol GPRC5A 516026
Bos taurus Mammals IFIT3 IFIT3 ncbigene_symbol IFIT3 509678
Bos taurus Mammals BAMBI BAMBI ncbigene_symbol BAMBI 530147
Bos taurus Mammals IL15 IL15 ncbigene_symbol IL15 281248
Bos taurus Mammals TLE4 TLE4 ncbigene_symbol TLE4 508893
Bos taurus Mammals DDX18 DDX18 ncbigene_symbol DDX18 519254
Bos taurus Mammals MYST4 MYST4 ncbigene_synonym KAT6B 535403
Bos taurus Mammals CTSW CTSW ncbigene_symbol CTSW 510967
Bos taurus Mammals NKX2-8 NKX2-8 ncbigene_symbol NKX2-8 539075
Bos taurus Mammals HMGN2 HMGN2 ncbigene_symbol HMGN2 512161
Bos taurus Mammals MYC MYC ncbigene_symbol MYC 511077
Bos taurus Mammals MÝST3 MYST3 ncbigene_synonym KAT6A 529373
Bos taurus Mammals RBBP7 RBBP7 ncbigene_symbol RBBP7 537402
Bos taurus Mammals PERP PERP ncbigene_symbol PERP 509485
Bos taurus Mammals SS18 SS18 ncbigene_symbol SS18 540947
Bos taurus Mammals TP53 TP53 ncbigene_symbol TP53 281542
Bos taurus Mammals PPP1R15A PPP1R15A ncbigene_symbol PPP1R15A 514688
Bos taurus Mammals TNPO2 TNPO2 ncbigene_symbol TNPO2 504589
Bos taurus Mammals ARID4A ARID4A ncbigene_symbol ARID4A 531515
Bos taurus Mammals NPDC1 NPDC1 ncbigene_symbol NPDC1 100125919
Bos taurus Mammals POLH POLH ncbigene_symbol POLH 513606
Bos taurus Mammals NFIC NFIC ncbigene_symbol NFIC 553098
Mus musculus Rodents GPRC5A GPRC5A ncbigene_symbol Gprc5a 232431
Mus musculus Rodents IFIT3 IFIT3 ncbigene_symbol Ifit3 15959
Mus musculus Rodents BAMBI BAMBI ncbigene_symbol Bambi 68010
Mus musculus Rodents IL15 IL15 ncbigene_symbol Il15 16168
Mus musculus Rodents TLE4 TLE4 ncbigene_symbol Tle4 21888
Mus musculus Rodents DDX18 DDX18 ncbigene_symbol Ddx18 66942
Mus musculus Rodents MYST4 MYST4 ncbigene_synonym Kat6b 54169
Mus musculus Rodents CTSW CTSW ncbigene_symbol Ctsw 13041
Mus musculus Rodents NKX2-8 NKX2-8 ncbigene_synonym Nkx2-9 18094
Mus musculus Rodents HMGN2 HMGN2 ncbigene_symbol Hmgn2 15331
Mus musculus Rodents MYC MYC ncbigene_symbol Myc 17869
Mus musculus Rodents MYC MYC ncbigene_synonym Nol3 78688
Mus musculus Rodents MÝST3 MYST3 ncbigene_synonym Kat6a 244349
Mus musculus Rodents RBBP7 RBBP7 ncbigene_symbol Rbbp7 245688
Mus musculus Rodents PERP PERP ncbigene_symbol Perp 64058
Mus musculus Rodents SS18 SS18 ncbigene_symbol Ss18 268996
Mus musculus Rodents TP53 TP53 ncbigene_synonym Trp53 22059
Mus musculus Rodents PPP1R15A PPP1R15A ncbigene_symbol Ppp1r15a 17872
Mus musculus Rodents TNPO2 TNPO2 ncbigene_symbol Tnpo2 212999
Mus musculus Rodents ARID4A ARID4A ncbigene_symbol Arid4a 238247
Mus musculus Rodents NPDC1 NPDC1 ncbigene_symbol Npdc1 18146
Mus musculus Rodents POLH POLH ncbigene_symbol Polh 80905
Mus musculus Rodents CDC2B CDC2B ncbigene_symbol Cdc2b 107833
Mus musculus Rodents NFIC NFIC ncbigene_symbol Nfic 18029
Danio rerio Vertebrates BAMBI BAMBI ncbigene_synonym bambia 83496
Danio rerio Vertebrates IL15 IL15 ncbigene_symbol il15 654826
Danio rerio Vertebrates DDX18 DDX18 ncbigene_symbol ddx18 321127
Danio rerio Vertebrates HMGN2 HMGN2 ncbigene_symbol hmgn2 569904
Danio rerio Vertebrates MYC MYC ncbigene_synonym myca 30686
Danio rerio Vertebrates MYC MYC ncbigene_synonym mycbp2 368439
Danio rerio Vertebrates MÝST3 MYST3 ncbigene_synonym kat6a 266966
Danio rerio Vertebrates RBBP7 RBBP7 ncbigene_synonym rbb4l 322129
Danio rerio Vertebrates PERP PERP ncbigene_symbol perp 494479
Danio rerio Vertebrates SS18 SS18 ncbigene_symbol ss18 326668
Danio rerio Vertebrates TP53 TP53 ncbigene_symbol tp53 30590
Danio rerio Vertebrates PPP1R15A PPP1R15A ncbigene_symbol ppp1r15a 797943
Danio rerio Vertebrates TNPO2 TNPO2 ncbigene_synonym tnpo2a 445499
Danio rerio Vertebrates ARID4A ARID4A ncbigene_symbol arid4a 327404
Danio rerio Vertebrates NPDC1 NPDC1 ncbigene_synonym npdc1b 556607
Danio rerio Vertebrates NPDC1 NPDC1 ncbigene_synonym npdc1a 794093
Danio rerio Vertebrates POLH POLH ncbigene_symbol polh 678520
Danio rerio Vertebrates NFIC NFIC ncbigene_symbol nfic 100005568

Chemical mentions

Word Match MeSH Name ChEBI
retinoic acid Tretinoin mesh:D014212 all-trans-retinoic acid chebi:15367

Disease mentions

Word Match MeSH Name DOID