Bimodal genes highlighted in KEGG ECM-receptor interaction diagram

Bimodal genes highlighted in KEGG ECM-receptor interaction diagram. Nodes representing switch-like genes are colored orange; remaining genes on the MG-U74Av2 array are shown in grey, and white blocks designate genes not on the array. Genes not in the organism-specific pathway for mouse are crossed out. Genes identified as switching in skeletal muscle samples with diabetes type I and type II are labeled with "I" and "II", respectively, with arrows indicating the direction of change in the disease state (▲ is low-to-high; ▼ is high-to-low).
Bimodal genes highlighted in KEGG ECM-receptor interaction diagram
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Publication

Switch-like genes populate cell communication pathways and are enriched for extracellular proteins. (2008) Adam Ertel, et al. BMC Genomics. 2008;9:3-3. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Drosophila melanogaster Invertebrates Integrin INTEGRIN ncbigene_synonym scb 36692
Drosophila melanogaster Invertebrates fi FI ncbigene_symbol fi 248652
Drosophila melanogaster Invertebrates HA HA ncbigene_symbol ha 251217
Drosophila melanogaster Invertebrates HAO HAO ncbigene_symbol Hao 3771779
Drosophila melanogaster Invertebrates Laminin LAMININ ncbigene_synonym LanB1 34068
Drosophila melanogaster Invertebrates Laminin LAMININ ncbigene_synonym LanA 38723
Drosophila melanogaster Invertebrates Laminin LAMININ ncbigene_synonym LanB2 39118
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym egh 31239
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym betaTub56D 37238
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym mys 44885
Drosophila melanogaster Invertebrates B1 B1 ncbigene_synonym Prosbeta1 46058
Drosophila melanogaster Invertebrates ВЗ B3 ncbigene_synonym rb 31381
Drosophila melanogaster Invertebrates ВЗ B3 ncbigene_synonym betaTub60D 37888
Drosophila melanogaster Invertebrates ВЗ B3 ncbigene_synonym Prosbeta3 41079
Drosophila melanogaster Invertebrates a2 A2 ncbigene_synonym Pen 34338
Drosophila melanogaster Invertebrates a2 A2 ncbigene_synonym alphaTub85E 41183
Drosophila melanogaster Invertebrates a2 A2 ncbigene_synonym Prosalpha2 41531
Drosophila melanogaster Invertebrates a2 A2 ncbigene_synonym nAChRalpha2 42919
Drosophila melanogaster Invertebrates BSP BSP ncbigene_symbol bsp 247936
Drosophila melanogaster Invertebrates llb LLB ncbigene_synonym l(3)89Ea 49073
Drosophila melanogaster Invertebrates lin LIN ncbigene_symbol lin 45325
Drosophila melanogaster Invertebrates lin LIN ncbigene_synonym drl 44355
Drosophila melanogaster Invertebrates CD36 CD36 ncbigene_synonym crq 33219
Drosophila melanogaster Invertebrates com COM ncbigene_symbol COM 5658320
Drosophila melanogaster Invertebrates com COM ncbigene_synonym comt 47091
Drosophila melanogaster Invertebrates com COM ncbigene_synonym compressed 248141
Drosophila melanogaster Invertebrates com COM ncbigene_synonym lncRNA:flam 26067356
Drosophila melanogaster Invertebrates B5 B5 ncbigene_synonym Prosbeta5 45269
Drosophila melanogaster Invertebrates al1 A11 ncbigene_synonym gus 35478
Drosophila melanogaster Invertebrates a5 A5 ncbigene_symbol a5 33317
Drosophila melanogaster Invertebrates a5 A5 ncbigene_synonym Prosalpha5 36951
Drosophila melanogaster Invertebrates aDO ADO ncbigene_symbol ado 45988
Drosophila melanogaster Invertebrates DA DA ncbigene_symbol da 34413
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL6A1 1291
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL6A2 1292
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL6A3 1293
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL6A5 256076
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL6A6 131873
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL7A1 1294
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL8A1 1295
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL8A2 1296
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL9A1 1297
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL9A2 1298
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL9A3 1299
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL10A1 1300
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL11A1 1301
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL11A2 1302
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL12A1 1303
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL13A1 1305
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL14A1 7373
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL15A1 1306
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL16A1 1307
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL17A1 1308
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL18A1 80781
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL19A1 1310
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL20A1 57642
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL21A1 81578
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL22A1 169044
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL23A1 91522
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL24A1 255631
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL25A1 84570
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL26A1 136227
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL27A1 85301
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL28A1 340267
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL1A1 1277
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL1A2 1278
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL4A1 1282
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL4A2 1284
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL4A3 1285
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL4A4 1286
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL4A5 1287
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL4A6 1288
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL5A1 1289
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL5A2 1290
Homo sapiens Primates Collagen COLLAGEN famplex_relations COL5A3 50509
Homo sapiens Primates HAO HAO ncbigene_synonym HAAO 23498
Homo sapiens Primates B1 B1 ncbigene_synonym B3GNT2 10678
Homo sapiens Primates B1 B1 ncbigene_synonym B3GNTL1 146712
Homo sapiens Primates CD44 CD44 ncbigene_symbol CD44 960
Homo sapiens Primates VWF VWF ncbigene_symbol VWF 7450
Homo sapiens Primates ВЗ B3 ncbigene_synonym EEF1B2P2 1934
Homo sapiens Primates ВЗ B3 ncbigene_synonym BHLHE22 27319
Homo sapiens Primates a2 A2 ncbigene_synonym GPR162 27239
Homo sapiens Primates BSP BSP ncbigene_synonym IBSP 3381
Homo sapiens Primates Chad CHAD ncbigene_symbol CHAD 1101
Homo sapiens Primates THBS THBS ncbigene_synonym THBS1 7057
Homo sapiens Primates THBS THBS famplex_relations THBS2 7058
Homo sapiens Primates THBS THBS famplex_relations THBS3 7059
Homo sapiens Primates THBS THBS famplex_relations THBS4 7060
Homo sapiens Primates THBS THBS famplex_relations COMP 1311
Homo sapiens Primates OPN OPN ncbigene_synonym SPP1 6696
Homo sapiens Primates THES THES ncbigene_synonym SKIC3 9652
Homo sapiens Primates llb LIB ncbigene_synonym LRRC15 131578
Homo sapiens Primates Sv2 SV2 ncbigene_synonym SV2A 9900
Homo sapiens Primates CD36 CD36 ncbigene_symbol CD36 948
Homo sapiens Primates B5 B5 ncbigene_synonym TUBB4A 10382
Homo sapiens Primates al1 A11 ncbigene_synonym IGKV3D-20 28874
Homo sapiens Primates aDO ADO ncbigene_symbol ADO 84890
Homo sapiens Primates CD47 CD47 ncbigene_symbol CD47 961
Homo sapiens Primates RHAMM RHAMM ncbigene_synonym HMMR 3161

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID