Regulation of the AHR-XRE pathway by NRF2

Schematic representation of regulation of the AHR-XRE pathway by NRF2. The figure illustrates that interaction of NRF2 with ARE in the promoter of Ahr induces transcription of Ahr and triggers downstream events, the subsequent upregulation of cytochrome P450s and inhibition of adipogenesis. sMAF, small MAF proteins.
Regulation of the AHR-XRE pathway by NRF2
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Publication

NRF2 Modulates Aryl Hydrocarbon Receptor Signaling: Influence on Adipogenesis . (2007) Soona Shin, et al. Mol Cell Biol. 2007 Oct;27(20):7188-7197. Figure: F7.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates NRF2 NRF2 ncbigene_synonym GABPA 2551
Homo sapiens Primates NRF2 NRF2 ncbigene_synonym NFE2L2 4780
Homo sapiens Primates KEAP1 KEAP1 ncbigene_symbol KEAP1 9817
Homo sapiens Primates Cyp1b1 CYP1B1 ncbigene_symbol CYP1B1 1545
Homo sapiens Primates P450s P450 ncbigene_synonym CYP2B6 1555
Homo sapiens Primates Ahr AHR ncbigene_symbol AHR 196
Homo sapiens Primates ARNT ARNT ncbigene_symbol ARNT 405
Homo sapiens Primates ARNT ARNT ncbigene_synonym MIA3 375056
Homo sapiens Primates Gst, GST ncbigene_synonym SLCO6A1 133482
Homo sapiens Primates Gst, GST ncbigene_synonym GSTK1 373156
Homo sapiens Primates Gst, GST famplex_relations GSTA1 2938
Homo sapiens Primates Gst, GST famplex_relations GSTA2 2939
Homo sapiens Primates Gst, GST famplex_relations GSTA3 2940
Homo sapiens Primates Gst, GST famplex_relations GSTA4 2941
Homo sapiens Primates Gst, GST famplex_relations GSTA5 221357
Homo sapiens Primates Gst, GST famplex_relations GSTM1 2944
Homo sapiens Primates Gst, GST famplex_relations GSTM2 2946
Homo sapiens Primates Gst, GST famplex_relations GSTM3 2947
Homo sapiens Primates Gst, GST famplex_relations GSTM4 2948
Homo sapiens Primates Gst, GST famplex_relations GSTM5 2949
Homo sapiens Primates Gst, GST famplex_relations GSTO1 9446
Homo sapiens Primates Gst, GST famplex_relations GSTO2 119391
Homo sapiens Primates Gst, GST famplex_relations GSTP1 2950
Homo sapiens Primates Gst, GST famplex_relations GSTT1 2952
Homo sapiens Primates Gst, GST famplex_relations GSTT2 2953
Homo sapiens Primates Gst, GST famplex_relations GSTZ1 2954
Homo sapiens Primates Gst, GST famplex_relations GSTT2B 653689

Chemical mentions

Word Match MeSH Name ChEBI
CDDO-Im NA mesh:C472829

Disease mentions

Word Match MeSH Name DOID