The secretory pathway under different ER stress conditions (t-PA secretion, tunicamycin and DTT) together with examples of genes that are transcriptionally induced or repressed

Model of the secretory pathway under different ER stress conditions (t-PA secretion, tunicamycin and DTT) together with examples of genes that are transcriptionally induced or repressed. The A. niger gene designation is provided where previously known or, otherwise, the S. cerevisiae gene name is provided. Red, genes up-regulated by 3 conditions; orange, genes up-regulated by 2 conditions; yellow, genes up-regulated by 1 condition; light blue, genes down-regulated by 1 condition; blue, genes down-regulated by 2 conditions. N, nucleus; ER, endoplasmic reticulum; E, endosome; V, vacuole; G, Golgi. ERAD is ER-associated degradation.
The secretory pathway under different ER stress conditions (t-PA secretion, tunicamycin and DTT) together with examples of genes that are transcriptionally induced or repressed
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Publication

Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger. (2007) Thomas Guillemette, et al. BMC Genomics. 2007;8:158-158. Figure: F5.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Saccharomyces cerevisiae S288C Plants and Fungi ALG2 ALG2 ncbigene_symbol ALG2 852815
Saccharomyces cerevisiae S288C Plants and Fungi RER2 RER2 ncbigene_symbol RER2 852287
Saccharomyces cerevisiae S288C Plants and Fungi ROT2 ROT2 ncbigene_symbol ROT2 852530
Saccharomyces cerevisiae S288C Plants and Fungi CWH41 CWH41 ncbigene_symbol CWH41 852857
Saccharomyces cerevisiae S288C Plants and Fungi ALG3 ALG3 ncbigene_symbol ALG3 852196
Saccharomyces cerevisiae S288C Plants and Fungi OST2 OST2 ncbigene_symbol OST2 854270
Saccharomyces cerevisiae S288C Plants and Fungi OST3 OST3 ncbigene_symbol OST3 854252
Saccharomyces cerevisiae S288C Plants and Fungi ALG7 ALG7 ncbigene_symbol ALG7 852545
Saccharomyces cerevisiae S288C Plants and Fungi STT3 STT3 ncbigene_symbol STT3 852862
Saccharomyces cerevisiae S288C Plants and Fungi MNS1 MNS1 ncbigene_symbol MNS1 853595
Saccharomyces cerevisiae S288C Plants and Fungi WBP1 WBP1 ncbigene_symbol WBP1 856716
Saccharomyces cerevisiae S288C Plants and Fungi RFT1 RFT1 ncbigene_symbol RFT1 852261
Saccharomyces cerevisiae S288C Plants and Fungi MNT2 MNT2 ncbigene_symbol MNT2 852635
Saccharomyces cerevisiae S288C Plants and Fungi Sell SEL1 ncbigene_synonym UBX2 854995
Saccharomyces cerevisiae S288C Plants and Fungi UTR2 UTR2 ncbigene_symbol UTR2 856671
Saccharomyces cerevisiae S288C Plants and Fungi GAS1 GAS1 ncbigene_symbol GAS1 855355
Saccharomyces cerevisiae S288C Plants and Fungi CRH1 CRH1 ncbigene_symbol CRH1 853102
Saccharomyces cerevisiae S288C Plants and Fungi SCW10 SCW10 ncbigene_symbol SCW10 855352
Saccharomyces cerevisiae S288C Plants and Fungi DSK2 DSK2 ncbigene_symbol DSK2 855319
Saccharomyces cerevisiae S288C Plants and Fungi HRD3 HRD3 ncbigene_symbol HRD3 850904
Saccharomyces cerevisiae S288C Plants and Fungi UBP13 UBP13 ncbigene_symbol UBP13 852212
Saccharomyces cerevisiae S288C Plants and Fungi TIR3 TIR3 ncbigene_symbol TIR3 854804
Saccharomyces cerevisiae S288C Plants and Fungi SEC27 SEC27 ncbigene_symbol SEC27 852740
Saccharomyces cerevisiae S288C Plants and Fungi ERD2 ERD2 ncbigene_symbol ERD2 852240
Saccharomyces cerevisiae S288C Plants and Fungi SEC20 SEC20 ncbigene_symbol SEC20 852109
Saccharomyces cerevisiae S288C Plants and Fungi SEC6 SEC6 ncbigene_symbol SEC6 854742
Saccharomyces cerevisiae S288C Plants and Fungi ОРIЗ OPI3 ncbigene_symbol OPI3 853536
Saccharomyces cerevisiae S288C Plants and Fungi USO1 USO1 ncbigene_symbol USO1 851501
Saccharomyces cerevisiae S288C Plants and Fungi SLY1 SLY1 ncbigene_symbol SLY1 851770
Saccharomyces cerevisiae S288C Plants and Fungi ERV41 ERV41 ncbigene_symbol ERV41 854935
Saccharomyces cerevisiae S288C Plants and Fungi ERV46 ERV46 ncbigene_symbol ERV46 851256
Saccharomyces cerevisiae S288C Plants and Fungi RUD3 RUD3 ncbigene_symbol RUD3 854391
Saccharomyces cerevisiae S288C Plants and Fungi УРТ31 YPT31 ncbigene_symbol YPT31 856753
Saccharomyces cerevisiae S288C Plants and Fungi ERG24 ERG24 ncbigene_symbol ERG24 855441
Saccharomyces cerevisiae S288C Plants and Fungi EMP47 EMP47 ncbigene_symbol EMP47 850496
Saccharomyces cerevisiae S288C Plants and Fungi MCR1 MCR1 ncbigene_symbol MCR1 853707
Saccharomyces cerevisiae S288C Plants and Fungi YIP1 YIP1 ncbigene_symbol YIP1 853082
Saccharomyces cerevisiae S288C Plants and Fungi ITR2 ITR2 ncbigene_symbol ITR2 854050
Saccharomyces cerevisiae S288C Plants and Fungi HNM1 HNM1 ncbigene_symbol HNM1 852803
Saccharomyces cerevisiae S288C Plants and Fungi ERG28 ERG28 ncbigene_symbol ERG28 856767
Saccharomyces cerevisiae S288C Plants and Fungi SEC61 SEC61 ncbigene_symbol SEC61 851095
Saccharomyces cerevisiae S288C Plants and Fungi SEC65 SEC65 ncbigene_symbol SEC65 854866
Saccharomyces cerevisiae S288C Plants and Fungi SEC63 SEC63 ncbigene_symbol SEC63 854428
Saccharomyces cerevisiae S288C Plants and Fungi SRP72 SRP72 ncbigene_symbol SRP72 855891
Saccharomyces cerevisiae S288C Plants and Fungi SEC71 SEC71 ncbigene_synonym SEC66 852469
Saccharomyces cerevisiae S288C Plants and Fungi SPC2 SPC2 ncbigene_symbol SPC2 854949
Saccharomyces cerevisiae S288C Plants and Fungi SPC3 SPC3 ncbigene_symbol SPC3 850755
Saccharomyces cerevisiae S288C Plants and Fungi SEC72 SEC72 ncbigene_symbol SEC72 850999
Saccharomyces cerevisiae S288C Plants and Fungi SBH2 SBH2 ncbigene_symbol SBH2 856740
Saccharomyces cerevisiae S288C Plants and Fungi SEC11 SEC11 ncbigene_symbol SEC11 854840
Saccharomyces cerevisiae S288C Plants and Fungi LHS1 LHS1 ncbigene_symbol LHS1 853789
Homo sapiens Primates ALG2 ALG2 ncbigene_symbol ALG2 85365
Homo sapiens Primates ALG2 ALG2 ncbigene_synonym PDCD6 10016
Homo sapiens Primates ostA OSTA ncbigene_synonym SLC51A 200931
Homo sapiens Primates CWH41 CWH41 ncbigene_synonym MOGS 7841
Homo sapiens Primates DPM2 DPM2 ncbigene_symbol DPM2 8818
Homo sapiens Primates ALG3 ALG3 ncbigene_symbol ALG3 10195
Homo sapiens Primates ALG3 ALG3 famplex_relations ALG9 79796
Homo sapiens Primates ALG3 ALG3 famplex_relations ALG12 79087
Homo sapiens Primates ALG3 ALG3 famplex_relations PIGB 9488
Homo sapiens Primates ALG3 ALG3 famplex_relations PIGM 93183
Homo sapiens Primates ALG3 ALG3 famplex_relations PIGV 55650
Homo sapiens Primates ALG3 ALG3 famplex_relations PIGZ 80235
Homo sapiens Primates ALG3 ALG3 famplex_relations POMT1 10585
Homo sapiens Primates ALG3 ALG3 famplex_relations POMT2 29954
Homo sapiens Primates OST2 OST2 ncbigene_synonym DAD1 1603
Homo sapiens Primates ALG7 ALG7 ncbigene_synonym DPAGT1 1798
Homo sapiens Primates STT3 STT3 famplex_relations STT3A 3703
Homo sapiens Primates STT3 STT3 famplex_relations STT3B 201595
Homo sapiens Primates MNS1 MNS1 ncbigene_symbol MNS1 55329
Homo sapiens Primates WBP1 WBP1 ncbigene_symbol WBP1 23559
Homo sapiens Primates WBP1 WBP1 ncbigene_synonym DDOST 1650
Homo sapiens Primates RFT1 RFT1 ncbigene_symbol RFT1 91869
Homo sapiens Primates RFT1 RFT1 ncbigene_synonym SLC19A1 6573
Homo sapiens Primates RFT1 RFT1 ncbigene_synonym SLC52A1 55065
Homo sapiens Primates Sell SELL ncbigene_symbol SELL 6402
Homo sapiens Primates Sell SELI ncbigene_synonym SELENOI 85465
Homo sapiens Primates chiA CHIA ncbigene_symbol CHIA 27159
Homo sapiens Primates UTR2 UTR2 ncbigene_synonym UTS2R 2837
Homo sapiens Primates GAS1 GAS1 ncbigene_symbol GAS1 2619
Homo sapiens Primates CRH1 CRH1 ncbigene_synonym CRH 1392
Homo sapiens Primates DSK2 DSK2 ncbigene_synonym UBQLN2 29978
Homo sapiens Primates DSK2 DSK2 ncbigene_synonym UBQLN1 29979
Homo sapiens Primates HRD3 HRD3 ncbigene_synonym SEL1L 6400
Homo sapiens Primates treA TREA ncbigene_synonym TREH 11181
Homo sapiens Primates ERD2 ERD2 ncbigene_synonym KDELR1 10945
Homo sapiens Primates SEC20 SEC20 ncbigene_synonym BNIP1 662
Homo sapiens Primates SEC6 SEC6 ncbigene_synonym EXOC3 11336
Homo sapiens Primates AT-1 AT-1 ncbigene_synonym SLC33A1 9197
Homo sapiens Primates USO1 USO1 ncbigene_symbol USO1 8615
Homo sapiens Primates SLY1 SLY1 ncbigene_synonym SCFD1 23256
Homo sapiens Primates ERV41 ERV41 ncbigene_synonym ERGIC2 51290
Homo sapiens Primates ERV46 ERV46 ncbigene_synonym ERGIC3 51614
Homo sapiens Primates ERG28 ERG28 ncbigene_symbol ERG28 11161
Homo sapiens Primates pdiA PDIA ncbigene_synonym ENPP2 5168
Homo sapiens Primates SEC61 SEC61 ncbigene_synonym SEC61A1 29927
Homo sapiens Primates SEC63 SEC63 ncbigene_symbol SEC63 11231
Homo sapiens Primates SRP72 SRP72 ncbigene_symbol SRP72 6731
Homo sapiens Primates P58IPK P58IPK ncbigene_synonym DNAJC3 5611
Homo sapiens Primates SPC2 SPC2 ncbigene_synonym PCSK2 5126
Homo sapiens Primates SPC3 SPC3 ncbigene_synonym PCSK1 5122
Homo sapiens Primates SPC3 SPC3 ncbigene_synonym SPCS3 60559

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID
Congenital disorder of glycosylation NA