Signaling Pathways in Yeast

Signaling Pathways in Yeast. Overview of signaling pathways in the baker's yeast S. cerevisiae. From left to right: HOG pathway activated by osmotic shock, pheromone pathway activated by pheromones secreted by cells of the opposite mating type, pseudohyphal growth pathway stimulated by starvation conditions, and the glucose sensing pathway. In each pathway, the activated receptor activates a cascade of intracellular processes including complex formation, phosphorylation and dephosphorylation, and transport steps. Most of these pathways comprise a MAP kinase cascade and transcription factors that regulate the expression of target genes. Besides this, the signaling pathways can directly interact with cell cycle progression and adaptation of metabolism.
Signaling Pathways in Yeast
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Publication

Mathematical modeling of intracellular signaling pathways. (2006) Edda Klipp, et al. BMC Neurosci. 2006;7(Suppl 1):S10-S10. Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates Sin1 SIN1 ncbigene_synonym MAPKAP1 79109
Homo sapiens Primates Gpr1 GPR1 ncbigene_synonym CMKLR2 2825
Homo sapiens Primates Cdc42 CDC42 ncbigene_symbol CDC42 998
Homo sapiens Primates Gpa2 GPA2 ncbigene_synonym GPHA2 170589
Homo sapiens Primates Ste20 STE20 ncbigene_synonym STK24 8428
Homo sapiens Primates AC ADCY famplex_relations ADCY1 107
Homo sapiens Primates AC ADCY famplex_relations ADCY2 108
Homo sapiens Primates AC ADCY famplex_relations ADCY3 109
Homo sapiens Primates AC ADCY famplex_relations ADCY4 196883
Homo sapiens Primates AC ADCY famplex_relations ADCY5 111
Homo sapiens Primates AC ADCY famplex_relations ADCY6 112
Homo sapiens Primates AC ADCY famplex_relations ADCY7 113
Homo sapiens Primates AC ADCY famplex_relations ADCY8 114
Homo sapiens Primates AC ADCY famplex_relations ADCY9 115
Homo sapiens Primates AC ADCY famplex_relations ADCY10 55811
Homo sapiens Primates Ssk1 SSK1 ncbigene_synonym BUB1B 701
Homo sapiens Primates MAP MAP ncbigene_synonym SGSM3 27352
Homo sapiens Primates Pdel PDE1 famplex_relations PDE1A 5136
Homo sapiens Primates Pdel PDE1 famplex_relations PDE1B 5153
Homo sapiens Primates Pdel PDE1 famplex_relations PDE1C 5137
Homo sapiens Primates Dig1,2 DIG1 ncbigene_synonym PTGR1 22949
Homo sapiens Primates Dig1,2 DIG2 ncbigene_synonym DDIT4 54541
Homo sapiens Primates Tpk1 TPK1 ncbigene_symbol TPK1 27010
Homo sapiens Primates Hot1 HOT1 ncbigene_synonym HMBOX1 79618
Homo sapiens Primates Smpl SMP1 ncbigene_synonym TMEM50A 23585
Homo sapiens Primates Smpl SMP1 ncbigene_synonym SPAG8 26206
Homo sapiens Primates SA1 SA1 ncbigene_synonym STAG1 10274
Saccharomyces cerevisiae S288C Plants and Fungi Sin1 SIN1 ncbigene_synonym SPT2 856908
Saccharomyces cerevisiae S288C Plants and Fungi Ste2 STE2 ncbigene_symbol STE2 850518
Saccharomyces cerevisiae S288C Plants and Fungi Sho1 SHO1 ncbigene_symbol SHO1 856854
Saccharomyces cerevisiae S288C Plants and Fungi Gpr1 GPR1 ncbigene_symbol GPR1 851527
Saccharomyces cerevisiae S288C Plants and Fungi Cdc24 CDC24 ncbigene_symbol CDC24 851190
Saccharomyces cerevisiae S288C Plants and Fungi Cdc42 CDC42 ncbigene_symbol CDC42 850930
Saccharomyces cerevisiae S288C Plants and Fungi Ypd1 YPD1 ncbigene_symbol YPD1 851363
Saccharomyces cerevisiae S288C Plants and Fungi Gpa2 GPA2 ncbigene_symbol GPA2 856741
Saccharomyces cerevisiae S288C Plants and Fungi Ras2 RAS2 ncbigene_symbol RAS2 855625
Saccharomyces cerevisiae S288C Plants and Fungi Ste20 STE20 ncbigene_symbol STE20 856382
Saccharomyces cerevisiae S288C Plants and Fungi Ssk1 SSK1 ncbigene_symbol SSK1 850692
Saccharomyces cerevisiae S288C Plants and Fungi Stel1 STE11 ncbigene_symbol STE11 851076
Saccharomyces cerevisiae S288C Plants and Fungi Ste50 STE50 ncbigene_symbol STE50 850325
Saccharomyces cerevisiae S288C Plants and Fungi Pdel PDE1 ncbigene_symbol PDE1 852644
Saccharomyces cerevisiae S288C Plants and Fungi Ssk2 SSK2 ncbigene_symbol SSK2 855765
Saccharomyces cerevisiae S288C Plants and Fungi Ste5 STE5 ncbigene_symbol STE5 851680
Saccharomyces cerevisiae S288C Plants and Fungi Ste7 STE7 ncbigene_symbol STE7 851396
Saccharomyces cerevisiae S288C Plants and Fungi Pbs2 PBS2 ncbigene_symbol PBS2 853313
Saccharomyces cerevisiae S288C Plants and Fungi Bcy1 BCY1 ncbigene_symbol BCY1 854778
Saccharomyces cerevisiae S288C Plants and Fungi Hog1 HOG1 ncbigene_symbol HOG1 850803
Saccharomyces cerevisiae S288C Plants and Fungi Fus3 FUS3 ncbigene_symbol FUS3 852265
Saccharomyces cerevisiae S288C Plants and Fungi Kss1 KSS1 ncbigene_symbol KSS1 852931
Saccharomyces cerevisiae S288C Plants and Fungi Tpk2 TPK2 ncbigene_symbol TPK2 855898
Saccharomyces cerevisiae S288C Plants and Fungi Dig1,2 DIG1 ncbigene_symbol DIG1 856058
Saccharomyces cerevisiae S288C Plants and Fungi Dig1,2 DIG2 ncbigene_symbol DIG2 852091
Saccharomyces cerevisiae S288C Plants and Fungi Tpk1 TPK1 ncbigene_symbol TPK1 853275
Saccharomyces cerevisiae S288C Plants and Fungi Tpk1/3 TPK3 ncbigene_symbol TPK3 853688
Saccharomyces cerevisiae S288C Plants and Fungi Hot1 HOT1 ncbigene_symbol HOT1 855208
Saccharomyces cerevisiae S288C Plants and Fungi Msn2,4 MSN2 ncbigene_symbol MSN2 855053
Saccharomyces cerevisiae S288C Plants and Fungi Msn2,4 MSN4 ncbigene_symbol MSN4 853803
Saccharomyces cerevisiae S288C Plants and Fungi Skol SKO1 ncbigene_symbol SKO1 855554
Saccharomyces cerevisiae S288C Plants and Fungi Smpl SMP1 ncbigene_symbol SMP1 852480
Saccharomyces cerevisiae S288C Plants and Fungi Flo8 FLO8 ncbigene_symbol FLO8 856845
Saccharomyces cerevisiae S288C Plants and Fungi Ste12 STE12 ncbigene_symbol STE12 856484

Chemical mentions

Word Match MeSH Name ChEBI
Glucose Glucose mesh:D005947 D-glucopyranose chebi:4167
Pheromone Pheromones mesh:D010675 pheromone chebi:26013

Disease mentions

Word Match MeSH Name DOID