Actin Dysregulation Mediates Nephrotoxicity of Cassiae Semen Aqueous Extracts
Schematic illustration showing dysregulation of actin dynamics by CSAEs via the RhoA–ROCK signaling pathway
Publication
Actin Dysregulation Mediates Nephrotoxicity of Cassiae Semen Aqueous Extracts (2024) Jinlan Yang, et al. Toxics. 2024 Aug;12(8). Figure: F13.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | claudinoccludin/JAM1/JAM4 | JAM4 | ncbigene_synonym | IGSF5 | 150084 |
| Homo sapiens | Primates | claudinoccludin/JAM1/JAM4 | JAM1 | ncbigene_synonym | F11R | 50848 |
| Homo sapiens | Primates | ZO-1 | ZO-1 | ncbigene_synonym | TJP1 | 7082 |
| Homo sapiens | Primates | RhoA | RHOA | ncbigene_symbol | RHOA | 387 |
| Homo sapiens | Primates | Rac1 | RAC1 | ncbigene_symbol | RAC1 | 5879 |
| Homo sapiens | Primates | Rac1 | RAC1 | ncbigene_synonym | RNASE1 | 6035 |
| Homo sapiens | Primates | CDC42 | CDC42 | ncbigene_symbol | CDC42 | 998 |
| Homo sapiens | Primates | ROCK | ROCK | famplex_relations | ROCK1 | 6093 |
| Homo sapiens | Primates | ROCK | ROCK | famplex_relations | ROCK2 | 9475 |
| Homo sapiens | Primates | cofilin | COFILIN | ncbigene_synonym | CFL1 | 1072 |
| Homo sapiens | Primates | cofilin | COFILIN | famplex_relations | CFL2 | 1073 |
| Homo sapiens | Primates | cofilin | COFILIN | famplex_relations | DSTN | 11034 |
| Homo sapiens | Primates | Actin | ACTIN | famplex_relations | ACTA1 | 58 |
| Homo sapiens | Primates | Actin | ACTIN | famplex_relations | ACTA2 | 59 |
| Homo sapiens | Primates | Actin | ACTIN | famplex_relations | ACTB | 60 |
| Homo sapiens | Primates | Actin | ACTIN | famplex_relations | ACTC1 | 70 |
| Homo sapiens | Primates | Actin | ACTIN | famplex_relations | ACTG1 | 71 |
| Homo sapiens | Primates | Actin | ACTIN | famplex_relations | ACTG2 | 72 |
| Homo sapiens | Primates | MLC | MLC | ncbigene_synonym | MLC1 | 23209 |
| Homo sapiens | Primates | BUN,KIM-1,NGAL,ẞ2M | KIM-1 | ncbigene_synonym | HAVCR1 | 26762 |
| Homo sapiens | Primates | BUN,KIM-1,NGAL,ẞ2M | NGAL | ncbigene_synonym | LCN2 | 3934 |
| Word | Match | MeSH | Name | ChEBI |
|---|
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|