FCERI signaling pathway

FCεRI signaling pathway. Created with BioRender.com
FCERI signaling pathway
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Publication

Anti-Allergic and Anti-Inflammatory Signaling Mechanisms of Natural Compounds/Extracts in In Vitro System of RBL-2H3 Cell: A Systematic Review (2024) Tekan S. Rana, et al. Cells. 2024 Aug;13(16). Figure: F1.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates IgE IGE ncbigene_synonym IGHE 3497
Homo sapiens Primates FCЄRI FCRI ncbigene_synonym FCGR1A 2209
Homo sapiens Primates FCЄRI FCRI ncbigene_synonym FCGR1BP 2210
Homo sapiens Primates FCERI FCERI ncbigene_synonym FCER1A 2205
Homo sapiens Primates FCERI FCERI ncbigene_synonym MS4A2 2206
Homo sapiens Primates LAT LAT ncbigene_symbol LAT 27040
Homo sapiens Primates LAT LAT ncbigene_synonym ORC3 23595
Homo sapiens Primates LAT LAT ncbigene_synonym SPNS1 83985
Homo sapiens Primates Lyn LYN ncbigene_symbol LYN 4067
Homo sapiens Primates Syk SYK ncbigene_symbol SYK 6850
Homo sapiens Primates Gads GADS ncbigene_synonym GRAP2 9402
Homo sapiens Primates PGads PGAD ncbigene_synonym PHGDH 26227
Homo sapiens Primates Fyn FYN ncbigene_symbol FYN 2534
Homo sapiens Primates Grb2 GRB2 ncbigene_symbol GRB2 2885
Homo sapiens Primates Gab2 GAB2 ncbigene_symbol GAB2 9846
Homo sapiens Primates PLCY PLCG famplex_relations PLCG1 5335
Homo sapiens Primates PLCY PLCG famplex_relations PLCG2 5336
Homo sapiens Primates Vav VAV ncbigene_synonym VAV1 7409
Homo sapiens Primates Vav VAV famplex_relations VAV2 7410
Homo sapiens Primates Vav VAV famplex_relations VAV3 10451
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CA 5290
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CB 5291
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CD 5293
Homo sapiens Primates PI3K PI3K ncbigene_synonym PIK3CG 5294
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R3 8503
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R4 30849
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R5 23533
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R6 146850
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R1 5295
Homo sapiens Primates PI3K PI3K famplex_relations PIK3R2 5296
Homo sapiens Primates Sos SOS ncbigene_synonym XYLT2 64132
Homo sapiens Primates Sos SOS famplex_relations SOS1 6654
Homo sapiens Primates Sos SOS famplex_relations SOS2 6655
Homo sapiens Primates RAC RAC ncbigene_synonym AKT1 207
Homo sapiens Primates RAC RAC famplex_relations RAC1 5879
Homo sapiens Primates RAC RAC famplex_relations RAC2 5880
Homo sapiens Primates RAC RAC famplex_relations RAC3 5881
Homo sapiens Primates RAC RAC famplex_relations RHOG 391
Homo sapiens Primates Ras RAS famplex_relations KRAS 3845
Homo sapiens Primates Ras RAS famplex_relations HRAS 3265
Homo sapiens Primates Ras RAS famplex_relations NRAS 4893
Homo sapiens Primates PDK PDK famplex_relations PDK1 5163
Homo sapiens Primates PDK PDK famplex_relations PDK2 5164
Homo sapiens Primates PDK PDK famplex_relations PDK3 5165
Homo sapiens Primates PDK PDK famplex_relations PDK4 5166
Homo sapiens Primates Raf RAF ncbigene_synonym ZHX2 22882
Homo sapiens Primates Raf RAF famplex_relations ARAF 369
Homo sapiens Primates Raf RAF famplex_relations BRAF 673
Homo sapiens Primates Raf RAF famplex_relations RAF1 5894
Homo sapiens Primates MKK4 MKK4 ncbigene_synonym MAP2K4 6416
Homo sapiens Primates MKK4/7MKK3/6 MKK6 ncbigene_synonym MAP2K6 5608
Homo sapiens Primates MKK3 MKK3 ncbigene_synonym MAP2K3 5606
Homo sapiens Primates MEK MEK ncbigene_synonym MAP2K7 5609
Homo sapiens Primates MEK MEK famplex_relations MAP2K1 5604
Homo sapiens Primates MEK MEK famplex_relations MAP2K2 5605
Homo sapiens Primates AKT AKT famplex_relations AKT2 208
Homo sapiens Primates AKT AKT famplex_relations AKT3 10000
Homo sapiens Primates ERK ERK ncbigene_synonym EPHB2 2048
Homo sapiens Primates ERK ERK ncbigene_synonym MAPK1 5594
Homo sapiens Primates ERK ERK famplex_relations MAPK3 5595
Homo sapiens Primates p38 P38 ncbigene_synonym CRK 1398
Homo sapiens Primates p38 P38 ncbigene_synonym MAPK14 1432
Homo sapiens Primates p38 P38 ncbigene_synonym AIMP2 7965
Homo sapiens Primates p38 P38 ncbigene_synonym AHSA1 10598
Homo sapiens Primates p38 P38 ncbigene_synonym POLDIP2 26073
Homo sapiens Primates p38 P38 famplex_relations MAPK11 5600
Homo sapiens Primates p38 P38 famplex_relations MAPK12 6300
Homo sapiens Primates p38 P38 famplex_relations MAPK13 5603
Homo sapiens Primates PKC PKC ncbigene_synonym PRRT2 112476
Homo sapiens Primates PKC PKC famplex_relations PRKCA 5578
Homo sapiens Primates PKC PKC famplex_relations PRKCB 5579
Homo sapiens Primates PKC PKC famplex_relations PRKCD 5580
Homo sapiens Primates PKC PKC famplex_relations PRKCE 5581
Homo sapiens Primates PKC PKC famplex_relations PRKCG 5582
Homo sapiens Primates PKC PKC famplex_relations PRKCH 5583
Homo sapiens Primates PKC PKC famplex_relations PRKCI 5584
Homo sapiens Primates PKC PKC famplex_relations PRKCQ 5588
Homo sapiens Primates PKC PKC famplex_relations PRKCZ 5590
Homo sapiens Primates PKC PKC famplex_relations PRKD3 23683
Homo sapiens Primates JNK JNK ncbigene_synonym MAPK8 5599
Homo sapiens Primates JNK JNK famplex_relations MAPK9 5601
Homo sapiens Primates JNK JNK famplex_relations MAPK10 5602
Homo sapiens Primates BCL10 BCL10 ncbigene_symbol BCL10 8915
Homo sapiens Primates MALT1 MALT1 ncbigene_symbol MALT1 10892
Homo sapiens Primates NF-kB NF-KB ncbigene_synonym NFKB1 4790
Homo sapiens Primates TNF-a TNF-A ncbigene_synonym TNF 7124
Homo sapiens Primates IL-3 IL-3 ncbigene_synonym IL3 3562
Homo sapiens Primates IL-13 IL-13 ncbigene_synonym IL13 3596
Homo sapiens Primates IL-5 IL-5 ncbigene_synonym IL5 3567
Homo sapiens Primates IL-4 IL-4 ncbigene_synonym IL4 3565

Chemical mentions

Word Match MeSH Name ChEBI
Ca2+ Ca2+ Ca(2+) chebi:29108
Ras RAS (1R)-N-(prop-2-yn-1-yl)indan-1-amine chebi:63620
MEK MEK butan-2-one chebi:28398
TNF-a TNF-a chebi:197439

Disease mentions

Word Match MeSH Name DOID