RIG-I-like receptor signaling pathway in antiviral immunity

The role of RIG-I-like receptor signaling pathway in antiviral immunity. BRD4 mediates IRF and NF-κB-dependent innate response networks through RIG-I and TLR3 signaling pathways. BRD4 can also regulate viral infection by interacting with interferon-stimulated genes (ISGs) and viral proteins
RIG-I-like receptor signaling pathway in antiviral immunity

Publication

A Review of the Bromodomain and Extraterminal Domain Epigenetic Reader Proteins: Function on Virus Infection and Cancer (2024) Mengli Wu, et al. Viruses. 2024 Jul;16(7). Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates RIG-I RIG-I ncbigene_synonym RIGI 23586
Homo sapiens Primates TBK1 TBK1 ncbigene_symbol TBK1 29110
Homo sapiens Primates IKK-ε IKK famplex_relations CHUK 1147
Homo sapiens Primates IKK-ε IKK famplex_relations IKBKB 3551
Homo sapiens Primates IKK-ε IKK famplex_relations IKBKG 8517
Homo sapiens Primates IKK-ε IKK famplex_relations IKBKE 9641
Homo sapiens Primates MAVS MAVS ncbigene_symbol MAVS 57506
Homo sapiens Primates IRF3 IRF3 ncbigene_symbol IRF3 3661
Homo sapiens Primates IRF7 IRF7 ncbigene_symbol IRF7 3665
Homo sapiens Primates IFN-α/ẞ IFN ncbigene_synonym IFNA1 3439
Homo sapiens Primates BRD4 BRD4 ncbigene_symbol BRD4 23476
Homo sapiens Primates Histone HISTONE famplex_relations H1-0 3005
Homo sapiens Primates Histone HISTONE famplex_relations H1-1 3024
Homo sapiens Primates Histone HISTONE famplex_relations H1-2 3006
Homo sapiens Primates Histone HISTONE famplex_relations H1-3 3007
Homo sapiens Primates Histone HISTONE famplex_relations H1-4 3008
Homo sapiens Primates Histone HISTONE famplex_relations H1-5 3009
Homo sapiens Primates Histone HISTONE famplex_relations H1-6 3010
Homo sapiens Primates Histone HISTONE famplex_relations H1-7 341567
Homo sapiens Primates Histone HISTONE famplex_relations H1-8 132243
Homo sapiens Primates Histone HISTONE famplex_relations H1-10 8971
Homo sapiens Primates Histone HISTONE famplex_relations NA NaN
Homo sapiens Primates Histone HISTONE famplex_relations H2AB1 474382
Homo sapiens Primates Histone HISTONE famplex_relations H2AJ 55766
Homo sapiens Primates Histone HISTONE famplex_relations H2AZ2 94239
Homo sapiens Primates Histone HISTONE famplex_relations H2AX 3014
Homo sapiens Primates Histone HISTONE famplex_relations MACROH2A1 9555
Homo sapiens Primates Histone HISTONE famplex_relations MACROH2A2 55506
Homo sapiens Primates Histone HISTONE famplex_relations H2AZ1 3015
Homo sapiens Primates Histone HISTONE famplex_relations H2AC1 221613
Homo sapiens Primates Histone HISTONE famplex_relations H2AC6 8334
Homo sapiens Primates Histone HISTONE famplex_relations H2AC7 3013
Homo sapiens Primates Histone HISTONE famplex_relations H2AC12 85235
Homo sapiens Primates Histone HISTONE famplex_relations H2AC14 8331
Homo sapiens Primates Histone HISTONE famplex_relations H2AC21 317772
Homo sapiens Primates Histone HISTONE famplex_relations H2AC20 8338
Homo sapiens Primates Histone HISTONE famplex_relations H2AC25 92815
Homo sapiens Primates Histone HISTONE famplex_relations H2BC1 255626
Homo sapiens Primates Histone HISTONE famplex_relations H2BC3 3018
Homo sapiens Primates Histone HISTONE famplex_relations H2BC5 3017
Homo sapiens Primates Histone HISTONE famplex_relations H2BC9 8345
Homo sapiens Primates Histone HISTONE famplex_relations H2BC11 8970
Homo sapiens Primates Histone HISTONE famplex_relations H2BC12 85236
Homo sapiens Primates Histone HISTONE famplex_relations H2BC13 8340
Homo sapiens Primates Histone HISTONE famplex_relations H2BC14 8342
Homo sapiens Primates Histone HISTONE famplex_relations H2BC15 8341
Homo sapiens Primates Histone HISTONE famplex_relations H2BC17 8348
Homo sapiens Primates Histone HISTONE famplex_relations H2BC18 440689
Homo sapiens Primates Histone HISTONE famplex_relations H2BC19P 337874
Homo sapiens Primates Histone HISTONE famplex_relations H2BC20P 337873
Homo sapiens Primates Histone HISTONE famplex_relations H2BC21 8349
Homo sapiens Primates Histone HISTONE famplex_relations H2BC26 128312
Homo sapiens Primates Histone HISTONE famplex_relations H2BC12L 54145
Homo sapiens Primates Histone HISTONE famplex_relations H2BW2 286436
Homo sapiens Primates Histone HISTONE famplex_relations H2BW1 158983
Homo sapiens Primates Histone HISTONE famplex_relations H3-4 8290
Homo sapiens Primates Histone HISTONE famplex_relations H3-5 440093
Homo sapiens Primates Histone HISTONE famplex_relations H4C7 8369
Homo sapiens Primates NF-kB NF-KB ncbigene_synonym NFKB1 4790
Homo sapiens Primates MDA5 MDA5 ncbigene_synonym IFIH1 64135

Chemical mentions

Word Match MeSH Name ChEBI

Disease mentions

Word Match MeSH Name DOID