The influence of curcumin on mammalian DHA synthesis pathway and its neuroprotective effect [61]
Schematic of the influence of curcumin on mammalian DHA synthesis pathway and its neuroprotective effect [61]. ALA: alpha-linolenic acid; DPA: docosapentaenoic acid; FADS2: fatty acid desaturase 2; Elov: elongase; BDNF: Brain-derived neurotrophic factor; TrkB: tropomyosin receptor kinase B; NF-κB: nuclear factor-kappa B; IL-6: interleukin-6; TNF: tumor necrosis factor; and iNOS: inducible nitric oxide synthase
![The influence of curcumin on mammalian DHA synthesis pathway and its neuroprotective effect [61]](https://europepmc.org/articles/PMC11201817/bin/biomedicines-12-01237-g002.jpg)
Publication
Combination Therapy for Sustainable Fish Oil Products: Improving Cognitive Function with n-3 PUFA and Natural Ingredients (2024) Anthony Arsecularatne, et al. Biomedicines. 2024 Jun;12(6). Figure: F2.| Organism | Group | Word | Match | Source | NCBI Symbol | NCBI ID |
|---|---|---|---|---|---|---|
| Homo sapiens | Primates | FADS2 | FADS2 | ncbigene_symbol | FADS2 | 9415 |
| Homo sapiens | Primates | FADS2 | FADS2 | ncbigene_synonym | RAPSN | 5913 |
| Homo sapiens | Primates | EPA | EPA | ncbigene_synonym | TIMP1 | 7076 |
| Homo sapiens | Primates | BDNF | BDNF | ncbigene_symbol | BDNF | 627 |
| Homo sapiens | Primates | BDNF | BDNF | ncbigene_synonym | BDNF-AS | 497258 |
| Homo sapiens | Primates | TrkB | TRKB | ncbigene_synonym | NTRK2 | 4915 |
| Homo sapiens | Primates | NFKB | NFKB | ncbigene_synonym | NFKB1 | 4790 |
| Homo sapiens | Primates | NFKB | NFKB | famplex_relations | RELA | 5970 |
| Homo sapiens | Primates | NFKB | NFKB | famplex_relations | RELB | 5971 |
| Homo sapiens | Primates | NFKB | NFKB | famplex_relations | REL | 5966 |
| Homo sapiens | Primates | NFKB | NFKB | famplex_relations | NFKB2 | 4791 |
| Homo sapiens | Primates | IL-6; | IL6 | ncbigene_symbol | IL6 | 3569 |
| Homo sapiens | Primates | TNF; | TNF | ncbigene_symbol | TNF | 7124 |
| Homo sapiens | Primates | ¡NOS | NOS | ncbigene_synonym | NOS1 | 4842 |
| Homo sapiens | Primates | ¡NOS | NOS | ncbigene_synonym | NOS2 | 4843 |
| Homo sapiens | Primates | ¡NOS | NOS | famplex_relations | NOS3 | 4846 |
| Word | Match | MeSH | Name | ChEBI |
|---|---|---|---|---|
| Curcumin | curcumin | curcumin | chebi:3962 | |
| DHA | DHA | docosahexaenoic acid | chebi:36005 | |
| ALA | ALA | L-alanyl-L-leucyl-L-alanine | chebi:158283 | |
| elements | elements | atom | chebi:33250 |
Disease mentions
| Word | Match | MeSH | Name | DOID |
|---|