Coloration in Equine: Overview of Candidate Genes Associated with Coat Color Phenotypes

Mechanism of regulation of the melanogenesis signaling pathway (eai04916) by coat-color-linked genes (MC1R, TYR, MITF, ASIP, and KIT)
Coloration in Equine: Overview of Candidate Genes Associated with Coat Color Phenotypes
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Coloration in Equine: Overview of Candidate Genes Associated with Coat Color Phenotypes (2024) Xiaotong Liu, et al. Animals (Basel). 2024 Jun;14(12). Figure: F2.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates MSH MSH ncbigene_synonym MSX2 4488
Homo sapiens Primates MSH MSH ncbigene_synonym POMC 5443
Homo sapiens Primates Gs GS famplex_relations GNAS 2778
Homo sapiens Primates Gs GS famplex_relations GNAL 2774
Homo sapiens Primates AC ADCY famplex_relations ADCY1 107
Homo sapiens Primates AC ADCY famplex_relations ADCY2 108
Homo sapiens Primates AC ADCY famplex_relations ADCY3 109
Homo sapiens Primates AC ADCY famplex_relations ADCY4 196883
Homo sapiens Primates AC ADCY famplex_relations ADCY5 111
Homo sapiens Primates AC ADCY famplex_relations ADCY6 112
Homo sapiens Primates AC ADCY famplex_relations ADCY7 113
Homo sapiens Primates AC ADCY famplex_relations ADCY8 114
Homo sapiens Primates AC ADCY famplex_relations ADCY9 115
Homo sapiens Primates AC ADCY famplex_relations ADCY10 55811
Homo sapiens Primates PKA PKA famplex_relations PRKAR1A 5573
Homo sapiens Primates PKA PKA famplex_relations PRKAR1B 5575
Homo sapiens Primates PKA PKA famplex_relations PRKAR2A 5576
Homo sapiens Primates PKA PKA famplex_relations PRKAR2B 5577
Homo sapiens Primates PKA PKA famplex_relations PRKACA 5566
Homo sapiens Primates PKA PKA famplex_relations PRKACB 5567
Homo sapiens Primates PKA PKA famplex_relations PRKACG 5568
Homo sapiens Primates CREB CREB ncbigene_synonym CREB1 1385
Homo sapiens Primates CREB CREB famplex_relations CREB3 10488
Homo sapiens Primates CREB CREB famplex_relations CREB5 9586
Homo sapiens Primates CREB CREB famplex_relations CREB3L1 90993
Homo sapiens Primates CREB CREB famplex_relations CREB3L2 64764
Homo sapiens Primates CREB CREB famplex_relations CREB3L3 84699
Homo sapiens Primates CREB CREB famplex_relations CREB3L4 148327
Homo sapiens Primates CREB CREB famplex_relations CREM 1390
Homo sapiens Primates CREB CREB famplex_relations ATF1 466
Homo sapiens Primates CREB CREB famplex_relations ATF2 1386
Homo sapiens Primates CBP CBP ncbigene_synonym CREBBP 1387
Homo sapiens Primates CBP CBP ncbigene_synonym EIF4E 1977
Homo sapiens Primates CBP CBP ncbigene_synonym OPN1LW 5956
Homo sapiens Primates CBP CBP ncbigene_synonym PAG1 55824
Homo sapiens Primates CBP CBP ncbigene_synonym PCBP4 57060
Homo sapiens Primates Wnt WNT famplex_relations WNT1 7471
Homo sapiens Primates Wnt WNT famplex_relations WNT2 7472
Homo sapiens Primates Wnt WNT famplex_relations WNT2B 7482
Homo sapiens Primates Wnt WNT famplex_relations WNT3 7473
Homo sapiens Primates Wnt WNT famplex_relations WNT3A 89780
Homo sapiens Primates Wnt WNT famplex_relations WNT4 54361
Homo sapiens Primates Wnt WNT famplex_relations WNT6 7475
Homo sapiens Primates Wnt WNT famplex_relations WNT7A 7476
Homo sapiens Primates Wnt WNT famplex_relations WNT7B 7477
Homo sapiens Primates Wnt WNT famplex_relations WNT8A 7478
Homo sapiens Primates Wnt WNT famplex_relations WNT8B 7479
Homo sapiens Primates Wnt WNT famplex_relations WNT9A 7483
Homo sapiens Primates Wnt WNT famplex_relations WNT9B 7484
Homo sapiens Primates Wnt WNT famplex_relations WNT10A 80326
Homo sapiens Primates Wnt WNT famplex_relations WNT10B 7480
Homo sapiens Primates Wnt WNT famplex_relations WNT11 7481
Homo sapiens Primates Wnt WNT famplex_relations WNT16 51384
Homo sapiens Primates Wnt WNT famplex_relations WNT5A 7474
Homo sapiens Primates Wnt WNT famplex_relations WNT5B 81029
Homo sapiens Primates Frizzled FZD famplex_relations FZD1 8321
Homo sapiens Primates Frizzled FZD famplex_relations FZD10 11211
Homo sapiens Primates Frizzled FZD famplex_relations FZD2 2535
Homo sapiens Primates Frizzled FZD famplex_relations FZD3 7976
Homo sapiens Primates Frizzled FZD famplex_relations FZD4 8322
Homo sapiens Primates Frizzled FZD famplex_relations FZD5 7855
Homo sapiens Primates Frizzled FZD famplex_relations FZD6 8323
Homo sapiens Primates Frizzled FZD famplex_relations FZD7 8324
Homo sapiens Primates Frizzled FZD famplex_relations FZD8 8325
Homo sapiens Primates Frizzled FZD famplex_relations FZD9 8326
Homo sapiens Primates Gq GQ famplex_relations GNAQ 2776
Homo sapiens Primates Gq GQ famplex_relations GNA11 2767
Homo sapiens Primates Gq GQ famplex_relations GNA14 9630
Homo sapiens Primates Gq GQ famplex_relations GNA15 2769
Homo sapiens Primates Dvl DVL ncbigene_synonym DVL1 1855
Homo sapiens Primates Dvl DVL ncbigene_synonym DVL1P1 8215
Homo sapiens Primates Dvl DVL famplex_relations DVL2 1856
Homo sapiens Primates Dvl DVL famplex_relations DVL3 1857
Homo sapiens Primates B-catenin CTNNB1 ncbigene_symbol CTNNB1 1499
Homo sapiens Primates TCF/LEF TCF ncbigene_synonym HNF4A 3172
Homo sapiens Primates MAPK MAPK famplex_relations MAPK1 5594
Homo sapiens Primates MAPK MAPK famplex_relations MAPK3 5595
Homo sapiens Primates MAPK MAPK famplex_relations MAPK11 5600
Homo sapiens Primates MAPK MAPK famplex_relations MAPK12 6300
Homo sapiens Primates MAPK MAPK famplex_relations MAPK13 5603
Homo sapiens Primates MAPK MAPK famplex_relations MAPK14 1432
Homo sapiens Primates MAPK MAPK famplex_relations MAPK8 5599
Homo sapiens Primates MAPK MAPK famplex_relations MAPK9 5601
Homo sapiens Primates MAPK MAPK famplex_relations MAPK10 5602
Homo sapiens Primates SCF SCF ncbigene_synonym KITLG 4254
Homo sapiens Primates c-Kit C-KIT ncbigene_synonym KIT 3815
Homo sapiens Primates Ras RAS famplex_relations KRAS 3845
Homo sapiens Primates Ras RAS famplex_relations HRAS 3265
Homo sapiens Primates Ras RAS famplex_relations NRAS 4893
Homo sapiens Primates Raf RAF ncbigene_synonym ZHX2 22882
Homo sapiens Primates Raf RAF famplex_relations ARAF 369
Homo sapiens Primates Raf RAF famplex_relations BRAF 673
Homo sapiens Primates Raf RAF famplex_relations RAF1 5894
Homo sapiens Primates MEK MEK ncbigene_synonym MAP2K7 5609
Homo sapiens Primates MEK MEK famplex_relations MAP2K1 5604
Homo sapiens Primates MEK MEK famplex_relations MAP2K2 5605
Homo sapiens Primates MITF MITF ncbigene_symbol MITF 4286
Homo sapiens Primates CAM CAM ncbigene_synonym CALM1 801
Homo sapiens Primates CAM CAM ncbigene_synonym CALM2 805
Homo sapiens Primates CAM CAM ncbigene_synonym CALM3 808
Homo sapiens Primates CAM CAM ncbigene_synonym KRIT1 889
Homo sapiens Primates CAM CAM ncbigene_synonym CAMKMT 79823
Homo sapiens Primates CAMK CAMK ncbigene_synonym CAMK4 814
Homo sapiens Primates CAMK CAMK ncbigene_synonym CAMK2G 818
Homo sapiens Primates CAMK CAMK famplex_relations CAMK1 8536
Homo sapiens Primates CAMK CAMK famplex_relations CAMK1D 57118
Homo sapiens Primates CAMK CAMK famplex_relations CAMK1G 57172
Homo sapiens Primates CAMK CAMK famplex_relations CAMK2A 815
Homo sapiens Primates CAMK CAMK famplex_relations CAMK2B 816
Homo sapiens Primates CAMK CAMK famplex_relations CAMK2D 817
Homo sapiens Primates ET-1 ET1 ncbigene_synonym EDN1 1906
Homo sapiens Primates ETB-R ETBR ncbigene_synonym EDNRB 1910
Homo sapiens Primates PLC PLC ncbigene_synonym HSPG2 3339
Homo sapiens Primates PLC PLC famplex_relations PLCE1 51196
Homo sapiens Primates PLC PLC famplex_relations PLCZ1 89869
Homo sapiens Primates PLC PLC famplex_relations PLCB1 23236
Homo sapiens Primates PLC PLC famplex_relations PLCB2 5330
Homo sapiens Primates PLC PLC famplex_relations PLCB3 5331
Homo sapiens Primates PLC PLC famplex_relations PLCB4 5332
Homo sapiens Primates PLC PLC famplex_relations PLCD1 5333
Homo sapiens Primates PLC PLC famplex_relations PLCD3 113026
Homo sapiens Primates PLC PLC famplex_relations PLCD4 84812
Homo sapiens Primates PLC PLC famplex_relations PLCG1 5335
Homo sapiens Primates PLC PLC famplex_relations PLCG2 5336
Homo sapiens Primates PKC PKC ncbigene_synonym PRRT2 112476
Homo sapiens Primates PKC PKC famplex_relations PRKCA 5578
Homo sapiens Primates PKC PKC famplex_relations PRKCB 5579
Homo sapiens Primates PKC PKC famplex_relations PRKCD 5580
Homo sapiens Primates PKC PKC famplex_relations PRKCE 5581
Homo sapiens Primates PKC PKC famplex_relations PRKCG 5582
Homo sapiens Primates PKC PKC famplex_relations PRKCH 5583
Homo sapiens Primates PKC PKC famplex_relations PRKCI 5584
Homo sapiens Primates PKC PKC famplex_relations PRKCQ 5588
Homo sapiens Primates PKC PKC famplex_relations PRKCZ 5590
Homo sapiens Primates PKC PKC famplex_relations PRKD3 23683
Homo sapiens Primates TYRP1 TYRP1 ncbigene_symbol TYRP1 7306
Homo sapiens Primates DCT DCT ncbigene_symbol DCT 1638

Chemical mentions

Word Match MeSH Name ChEBI
MSH MSH mycothiol chebi:16768
ASP Asp aspartic acid chebi:22660
CAMP cAMP adenosine 3',5'-(hydrogen phosphate) chebi:17489
DNA DNA deoxyribonucleic acids chebi:16991
DNA DNA deoxyribonucleic acids chebi:16991
Ras RAS (1R)-N-(prop-2-yn-1-yl)indan-1-amine chebi:63620
MEK MEK butan-2-one chebi:28398
TYR Tyr tyrosine chebi:18186
Tyrosine Tyrosine tyrosine chebi:18186
Tyrosine Tyrosine tyrosine chebi:18186
TYR Tyr tyrosine chebi:18186
DNA DNA deoxyribonucleic acids chebi:16991

Disease mentions

Word Match MeSH Name DOID
Melanoma melanoma melanoma DOID:1909