Gene expression changes in GO terms: (A) base excision repair, (B) mismatch repair, and (C) homologous recombination pathways in response to high–THC extract #18 compared to DMSO control in the HT–29 CRC cell line

Gene expression changes in GO terms: (A) base excision repair, (B) mismatch repair, and (C) homologous recombination pathways in response to high–THC extract #18 compared to DMSO control in the HT–29 CRC cell line. The genes are coloured according to the difference in expression level between treatment and control for each sample. Red colour shows upregulation and green downregulation relative to the treatment group. Data based on GAGE unidirectional analysis
Gene expression changes in GO terms: (A) base excision repair, (B) mismatch repair, and (C) homologous recombination pathways in response to high–THC extract #18 compared to DMSO control in the HT–29 CRC cell line
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Publication

Targeting Colorectal Cancer: Unravelling the Transcriptomic Impact of Cisplatin and High-THC Cannabis Extract (2024) Viktoriia Cherkasova, et al. Int J Mol Sci. 2024 Apr;25(8). Figure: F8.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates BASE BASE ncbigene_synonym BPIFA4P 317716
Homo sapiens Primates dal DAI ncbigene_synonym ZBP1 81030
Homo sapiens Primates typ TYP ncbigene_synonym DUSP4 1846
Homo sapiens Primates APR2 APR2 ncbigene_synonym FAM215A 23591
Homo sapiens Primates Par PAR ncbigene_synonym NR1I2 8856
Homo sapiens Primates Par PAR ncbigene_synonym JTB 10899
Homo sapiens Primates col COI ncbigene_synonym COX1 4512
Homo sapiens Primates Red RED ncbigene_synonym IK 3550
Homo sapiens Primates Red RED ncbigene_synonym DYRK3 8444
Homo sapiens Primates APEX APEX ncbigene_synonym APEX1 328
Homo sapiens Primates Mel MEL ncbigene_synonym RAB8A 4218
Homo sapiens Primates Mel MEL ncbigene_synonym MAP2K1 5604
Homo sapiens Primates MDHA MDHA ncbigene_synonym MDH1 4190
Homo sapiens Primates Temp TEMP ncbigene_synonym C1orf210 149466
Homo sapiens Primates MUH MUH ncbigene_synonym HPP1 780897
Homo sapiens Primates MSH MSH ncbigene_synonym MSX2 4488
Homo sapiens Primates MSH MSH ncbigene_synonym POMC 5443
Homo sapiens Primates MSH2 MSH2 ncbigene_symbol MSH2 4436
Homo sapiens Primates MSH3 MSH3 ncbigene_symbol MSH3 4437
Homo sapiens Primates Heli HE2 ncbigene_synonym SPAG11B 10407
Homo sapiens Primates Heli HE2 ncbigene_synonym SPAG11A 653423
Homo sapiens Primates Rad51B RAD51B ncbigene_symbol RAD51B 5890
Homo sapiens Primates Mull MU2 ncbigene_synonym AP2M1 1173
Homo sapiens Primates Mull MU2 ncbigene_synonym AP1M2 10053
Homo sapiens Primates BLM BLM ncbigene_symbol BLM 641
Homo sapiens Primates ATM ATM ncbigene_symbol ATM 472
Homo sapiens Primates comp COMP ncbigene_symbol COMP 1311
Homo sapiens Primates MRX MRX ncbigene_synonym DLG3 1741
Homo sapiens Primates MRX MRX ncbigene_synonym ABCG2 9429
Homo sapiens Primates MRN MRN famplex_relations MRE11 4361
Homo sapiens Primates MRN MRN famplex_relations NBN 4683
Homo sapiens Primates MRN MRN famplex_relations RAD50 10111
Homo sapiens Primates MRN MRN famplex_relations WDCP 80304
Homo sapiens Primates Mell MEI1 ncbigene_symbol MEI1 150365
Homo sapiens Primates RPA RPA ncbigene_synonym RPA1 6117
Homo sapiens Primates RPA RPA famplex_relations RPA2 6118
Homo sapiens Primates RPA RPA famplex_relations RPA3 6119
Homo sapiens Primates BRCA2 BRCA2 ncbigene_symbol BRCA2 675
Homo sapiens Primates PALB2 PALB2 ncbigene_symbol PALB2 79728
Homo sapiens Primates DBA DBA ncbigene_synonym RPS19 6223
Homo sapiens Primates PC PC ncbigene_symbol PC 5091
Homo sapiens Primates PHA PHA ncbigene_synonym LBR 3930
Homo sapiens Primates kir KIR ncbigene_synonym GEM 2669
Homo sapiens Primates kir KIR ncbigene_synonym KIR3DL1 3811
Homo sapiens Primates Mut MUT ncbigene_synonym MMUT 4594

Chemical mentions

Word Match MeSH Name ChEBI
dal DAL D-alanine chebi:15570
DHA DHA docosahexaenoic acid chebi:36005
DBA DBA chebi:35299
PHA PHA chebi:78037
DSER DSer D-serine residue chebi:29998

Disease mentions

Word Match MeSH Name DOID