PIAS family in cancer: from basic mechanisms to clinical applications

PIAS as downregulators of JAK/STAT, Smed signaling pathways, and NF kb pathway
PIAS family in cancer: from basic mechanisms to clinical applications
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Publication

PIAS family in cancer: from basic mechanisms to clinical applications (2024) Xiaomeng Li, et al. Front Oncol. 2024;14(NA). Figure: F3.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates via VIA ncbigene_synonym SEMA6A 57556
Homo sapiens Primates JAK JAK famplex_relations JAK1 3716
Homo sapiens Primates JAK JAK famplex_relations JAK2 3717
Homo sapiens Primates JAK JAK famplex_relations JAK3 3718
Homo sapiens Primates JAK JAK famplex_relations TYK2 7297
Homo sapiens Primates IFN IFN ncbigene_synonym IFNA1 3439
Homo sapiens Primates Smad SMAD famplex_relations SMAD1 4086
Homo sapiens Primates Smad SMAD famplex_relations SMAD4 4089
Homo sapiens Primates Smad SMAD famplex_relations SMAD5 4090
Homo sapiens Primates Smad SMAD famplex_relations SMAD6 4091
Homo sapiens Primates Smad SMAD famplex_relations SMAD7 4092
Homo sapiens Primates Smad SMAD famplex_relations SMAD9 4093
Homo sapiens Primates Smad SMAD famplex_relations SMAD2 4087
Homo sapiens Primates Smad SMAD famplex_relations SMAD3 4088
Homo sapiens Primates TGF-B TGFB ncbigene_synonym TGFB1 7040
Homo sapiens Primates TGF-B TGFB famplex_relations TGFB2 7042
Homo sapiens Primates TGF-B TGFB famplex_relations TGFB3 7043
Homo sapiens Primates LPS LPS ncbigene_synonym IRF6 3664
Homo sapiens Primates TNF-α, TNF ncbigene_symbol TNF 7124
Homo sapiens Primates NF-kappaB NF-KAPPAB ncbigene_synonym NFKB1 4790
Homo sapiens Primates TBRI TBRI ncbigene_synonym TGFBR1 7046
Homo sapiens Primates STAT STAT ncbigene_synonym SOAT1 6646
Homo sapiens Primates STAT STAT famplex_relations STAT1 6772
Homo sapiens Primates STAT STAT famplex_relations STAT2 6773
Homo sapiens Primates STAT STAT famplex_relations STAT3 6774
Homo sapiens Primates STAT STAT famplex_relations STAT4 6775
Homo sapiens Primates STAT STAT famplex_relations STAT6 6778
Homo sapiens Primates STAT STAT famplex_relations STAT5A 6776
Homo sapiens Primates STAT STAT famplex_relations STAT5B 6777
Homo sapiens Primates IKK IKK famplex_relations CHUK 1147
Homo sapiens Primates IKK IKK famplex_relations IKBKB 3551
Homo sapiens Primates IKK IKK famplex_relations IKBKG 8517
Homo sapiens Primates IKK IKK famplex_relations IKBKE 9641
Homo sapiens Primates IKK IKK famplex_relations TBK1 29110
Homo sapiens Primates P56 P56 ncbigene_synonym IFIT1 3434
Homo sapiens Primates P56 P56 ncbigene_synonym PSMC1 5700
Homo sapiens Primates P56 P56 ncbigene_synonym CDKL2 8999
Homo sapiens Primates P56 P56 ncbigene_synonym CCDC91 55297
Homo sapiens Primates P56 P56 ncbigene_synonym H3P45 115482705
Homo sapiens Primates P50 P50 ncbigene_synonym CD40 958
Homo sapiens Primates P50 P50 ncbigene_synonym ARHGEF7 8874
Homo sapiens Primates P50 P50 ncbigene_synonym ASCC1 51008
Homo sapiens Primates P50 P50 ncbigene_synonym H3P40 115482723
Homo sapiens Primates PIAS1 PIAS1 ncbigene_symbol PIAS1 8554
Homo sapiens Primates PIAS3 PIAS3 ncbigene_symbol PIAS3 10401
Homo sapiens Primates PIAS4 PIAS4 ncbigene_symbol PIAS4 51588
Homo sapiens Primates DMC DMC ncbigene_synonym DYM 54808
Homo sapiens Primates DMC DMC ncbigene_synonym CXCL17 284340

Chemical mentions

Word Match MeSH Name ChEBI
Nucleus nucleus nucleus chebi:33252
DMC DMC dimethyl carbonate chebi:36596

Disease mentions

Word Match MeSH Name DOID