Saponins activate the TLRs signaling pathway through TLRs, upregulate class I and II MHC molecules in APCs, and promote antigen capture, processing, and presentation

Saponins activate the TLRs signaling pathway through TLRs, upregulate class I and II MHC molecules in APCs, and promote antigen capture, processing, and presentation. (The figure was created using BioRender)
Saponins activate the TLRs signaling pathway through TLRs, upregulate class I and II MHC molecules in APCs, and promote antigen capture, processing, and presentation
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Publication

Potential Immunoregulatory Mechanism of Plant Saponins: A Review (2024) Liuhong Shen, et al. Molecules. 2024 Jan;29(1). Figure: F3.

Gene mentions


Organism Group Word Match Source NCBI Symbol NCBI ID
Homo sapiens Primates TLRs TLR famplex_relations TLR1 7096
Homo sapiens Primates TLRs TLR famplex_relations TLR2 7097
Homo sapiens Primates TLRs TLR famplex_relations TLR3 7098
Homo sapiens Primates TLRs TLR famplex_relations TLR4 7099
Homo sapiens Primates TLRs TLR famplex_relations TLR5 7100
Homo sapiens Primates TLRs TLR famplex_relations TLR6 10333
Homo sapiens Primates TLRs TLR famplex_relations TLR7 51284
Homo sapiens Primates TLRs TLR famplex_relations TLR8 51311
Homo sapiens Primates TLRs TLR famplex_relations TLR9 54106
Homo sapiens Primates TLRs TLR famplex_relations TLR10 81793
Homo sapiens Primates CD86 CD86 ncbigene_symbol CD86 942
Homo sapiens Primates CD80 CD80 ncbigene_symbol CD80 941
Homo sapiens Primates CD4 CD4 ncbigene_symbol CD4 920
Homo sapiens Primates CD28 CD28 ncbigene_symbol CD28 940
Homo sapiens Primates MHC MHC ncbigene_synonym HLA-C 3107
Homo sapiens Primates TCR TCR ncbigene_synonym TRBV20OR9-2 6962
Homo sapiens Primates TCR TCR famplex_relations TRA 6955
Homo sapiens Primates TCR TCR famplex_relations TRB 6957
Homo sapiens Primates TCR TCR famplex_relations TRD 6964
Homo sapiens Primates TCR TCR famplex_relations TRG 6965
Homo sapiens Primates (APC) APC ncbigene_symbol APC 324
Homo sapiens Primates (APC) APC ncbigene_synonym PROC 5624

Chemical mentions

Word Match MeSH Name ChEBI
Saponins saponins chebi:26605

Disease mentions

Word Match MeSH Name DOID